期刊
FEBS LETTERS
卷 584, 期 12, 页码 2516-2525出版社
WILEY
DOI: 10.1016/j.febslet.2010.04.021
关键词
Accessory subunit; Assembly; Membrane protein; Mitochondria; Oxidative phosphorylation; Photosystem
资金
- Cluster of Excellence Frankfurt Macromolecular Complexes at the Goethe University Frankfurt (DFG) [115]
The large membrane protein complexes of mitochondrial oxidative phosphorylation are composed of central subunits that are essential for their bioenergetic core function and accessory subunits that may assist in regulation, assembly or stabilization. Although sequence conservation is low, a significant proportion of the accessory subunits is characterized by a common single transmembrane (STMD) topology. The STMD signature is also found in subunits of other membrane protein complexes. We hypothesize that the general function of STMD subunits is to organize the hydrophobic subunits of large membrane protein complexes in specialized environments like the inner mitochondrial membrane. (C) 2010 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据