期刊
FEBS LETTERS
卷 584, 期 9, 页码 1678-1684出版社
WILEY
DOI: 10.1016/j.febslet.2009.10.051
关键词
Cell membrane; Lipid microdomain; Theory; Modeling
资金
- NSF at Princeton University [DMR-0449184, DMR-0213706]
Compositional lipid microdomains (lipid raft) in plasma membranes are believed to be important components of many cellular processes. The biophysical mechanisms by which cells regulate the size, lifetime, and spatial localization of these domains are rather poorly understood at the moment. Over the years, experimental studies of raft formation have inspired several phenomenological theories and speculations incorporating a wide variety of thermodynamic assumptions regarding lipid-lipid and lipid-protein interactions, and the potential role of active cellular processes on membrane structure. Here we critically review and discuss these theories, models, and speculations, and present our view on future directions. (C) 2009 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据