Sphingolipids and membrane environments for caveolin

Caveolin-1, and probably also -2 and -3, can organize multimolecular membrane complexes involved in transmembrane traffic, cell adhesion and signal transduction. In this review, we discuss on the importance of caveolin membrane environment in regulating the architecture and function of such complexes, with a special emphasis on the role of sphingolipids. (C) 2009 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.