期刊
FEBS LETTERS
卷 583, 期 22, 页码 3711-3717出版社
WILEY
DOI: 10.1016/j.febslet.2009.10.076
关键词
Leaf polarity; miRNA165a; miRNA166a; Transcriptional regulation; Arabidopsis
资金
- Shanghai Institutes for Biological Sciences
- Chinese National Scientific Foundation [30630041, 30721061]
- Chinese Academy of Sciences [KSCX2-YW-N-016/057]
During leaf development, polarity formation is critical for leaf morphogenesis and functions. This process is regulated by several components including two microRNAs, miR165 and 166, which negatively regulate transcription factor genes PHABULOSA, PHAVOLUTA and REVOLUTA. Although miR165 and 166 are known to be accumulated in the abaxial leaf domain, how this pattern is determined is largely unknown. Here we report that the MIR165a and 166a genes are predominantly transcribed in the abaxial epidermis, and this transcript distribution pattern is controlled by two types of cis-acting elements. Our results suggest a model for the polar accumulation of MIR165 and 166 transcripts. (C) 2009 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
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