期刊
FEBS LETTERS
卷 583, 期 1, 页码 180-184出版社
WILEY
DOI: 10.1016/j.febslet.2008.11.050
关键词
Pi regulation; Woronin body; hex-1; hsp-70; pacC; nuc-1
资金
- FAPESP
- CNPq
- CAPES
- FAEPA
The Woronin body, a septal pore-associated organelle specific to filamentous ascomycetes, is crucial for preventing cytoplasmic bleeding after hyphal injury. In this study, we show that T1hex-1 transcript and a variant splicing T2hex-1 transcript are up-regulated at alkaline pH. We also show that both hex-1 transcripts are overexpressed in the preg(c), nuc-1(RIP), and pacC(ko) mutant strains of Neurospora crassa grown under conditions of phosphate shortage at alkaline pH, suggesting that hex-1 transcription may be coregulated by these genes. In addition, we present evidence that N. crassa PacC also has metabolic functions at acidic pH. (C) 2008 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.
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