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Cannabinoid CB2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation
K. L. Wright et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Cannabinoid CB2 receptors in human brain inflammation
C. Benito et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
The cannabinoid receptors are required for ultraviolet-induced inflammation and skin cancer development
Duo Zheng et al.
CANCER RESEARCH (2008)
Role of cannabinoids and endocannabinoids in cerebral ischemia
Cecilia J. Hillard
CURRENT PHARMACEUTICAL DESIGN (2008)
SERENADE: The Study Evaluating Rimonabant Efficacy in Drug-Naive Diabetic Patients Effects of monotherapy with rimonabant, the first selective CB1 receptor antagonist, on glycemic control, body weight, and lipid profile in drug-naive type 2 diabetes
Julio Rosenstock et al.
DIABETES CARE (2008)
The endocannabinoid system in obesity and type 2 diabetes
V. Di Marzo
DIABETOLOGIA (2008)
Cannabis and schizophrenia: towards a cannabinoid hypothesis of schizophrenia
Kirsten R Müller-Vahl et al.
Expert Review of Neurotherapeutics (2008)
Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects
A. A. Izzo et al.
GUT (2008)
Modulation of the endocannabinoid system in cardiovascular disease - Therapeutic potential and limitations
Pal Pacher et al.
HYPERTENSION (2008)
Cannabinoids in pancreatic cancer:: Correlation with survival and pain
Christoph W. Michalski et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
Effect of rimonabant on progression of atherosclerosis in patients with abdominal obesity and coronary artery disease -: The STRADIVARIUS randomized controlled trial
Steven E. Nissen et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2008)
Endocannabinoids and the Control of Energy Homeostasis
George Kunos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-n-acyl ethanolamine precursors in mouse brain
Gabriel M. Simon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The CB2 cannabinoid receptor controls myeloid progenitor trafficking
Javier Palazuelos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Targeting endocannabinoid degradation protects against experimental colitis in mice:: involvement of CB1 and CB2 receptors
Martin A. Storr et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2008)
The role of the endocannabinoid system in atherosclerosis
F. Mach et al.
JOURNAL OF NEUROENDOCRINOLOGY (2008)
Endocannabinoids and the regulation of bone metabolism
I. Bab et al.
JOURNAL OF NEUROENDOCRINOLOGY (2008)
Selective Activation of Cannabinoid CB2 Receptors Suppresses Neuropathic Nociception Induced by Treatment with the Chemotherapeutic Agent Paclitaxel in Rats
Elizabeth J. Rahn et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
Targeting the endocannabinoid system: to enhance or reduce?
Vincenzo Di Marzo
NATURE REVIEWS DRUG DISCOVERY (2008)
Multiple pathways involved in the biosynthesis of anandamide
Jie Liu et al.
NEUROPHARMACOLOGY (2008)
Regional distribution and effects of postmortal delay on endocannabinoid content of the human brain
M. Palkovits et al.
NEUROSCIENCE (2008)
Cortical expression of brain derived neurotrophic factor and type-1 cannabinoid receptor after striatal excitotoxic lesions
Z. De March et al.
NEUROSCIENCE (2008)
Modulation of the balance between cannabinoid CB1 and CB2 receptor activation during cerebral ischemic/reperfusion injury
M. Zhang et al.
NEUROSCIENCE (2008)
Cannabinoids Reduce Markers of Inflammation and Fibrosis in Pancreatic Stellate Cells
Christoph W. Michalski et al.
PLOS ONE (2008)
Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis
Denise Richardson et al.
ARTHRITIS RESEARCH & THERAPY (2008)
Play an ADAGIO with a STRADIVARIUS: the right patient for CB1 receptor antagonists?
Vincenzo Di Marzo
NATURE CLINICAL PRACTICE CARDIOVASCULAR MEDICINE (2008)
Presence of functional cannabinoid receptors in human endocrine pancreas
F. J. Bermudez-Silva et al.
DIABETOLOGIA (2008)
Regression of fibrosis after chronic stimulation of cannabinoid CB2 receptor in cirrhotic rats
Javier Munoz-Luque et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
Pivotal Advance:: Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis
Mohanraj Rajesh et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
CB2-receptor stimulation attenuates TNF-α-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion
Mohanraj Rajesh et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats
Sandor Batkai et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Pharmacological inhibition of CB1 cannabinoid raceptor protects against doxorubicin-induced cardiotoxicity
Partha Mukhopadhyay et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2007)
Cannabinoid CB2 receptor activation decreases cerebral infarction in a mouse focal ischemia/reperfusion model
Ming Zhang et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)
Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors
Nitin Agarwal et al.
NATURE NEUROSCIENCE (2007)
Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury
Sandor Batkai et al.
FASEB JOURNAL (2007)
Cannabinoids ameliorate pain and reduce disease pathology in cerulein-induced acute pancreatitis
Christoph W. Michalski et al.
GASTROENTEROLOGY (2007)
The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset
Jennifer L. Shoemaker et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells
Katarzyna Maresz et al.
NATURE MEDICINE (2007)
Endocannabinoid receptor CB2 in nonalcoholic fatty liver disease
N. Mendez-Sanchez et al.
LIVER INTERNATIONAL (2007)
Cannabinoid CB1 and CB2 receptors and fatty acid amide hydrolase are specific markers of plaque cell subtypes in human multiple sclerosis
Cristina Benito et al.
JOURNAL OF NEUROSCIENCE (2007)
Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors
Christel Rousseaux et al.
NATURE MEDICINE (2007)
Cannabinoid CB2 receptor: a new target for controlling neural cell survival?
Javier Fernandez-Ruiz et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2007)
The endocannabinoid system in targeting inflammatory neurodegenerative diseases
Diego Centonze et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2007)
The role of the cannabinoid CB2 receptor in pain transmission and therapeutic potential of small molecule CB2 receptor agonists
G. T. Whiteside et al.
CURRENT MEDICINAL CHEMISTRY (2007)
Cannabinoid receptors as novel targets for the treatment of melanoma
Cristina Blazquez et al.
FASEB JOURNAL (2006)
AM1241, a cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis
Kathline Kim et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
Jekyll and Hyde: Two faces of cannabinoid signaling in male and female fertility
Haibin Wang et al.
ENDOCRINE REVIEWS (2006)
Agonists of cannabinoid receptor 1 and 2 inhibit experimental colitis induced by oil of mustard and by dextran sulfate sodium
Edward S. Kimball et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2006)
CB2 cannabinoid receptor mediation of antinociception
Mohab M. Ibrahim et al.
PAIN (2006)
The emerging role of the endocannabinoid system in endocrine regulation and energy balance
U Pagotto et al.
ENDOCRINE REVIEWS (2006)
The endocannabinoid system as an emerging target of pharmacotherapy
Pal Pacher et al.
PHARMACOLOGICAL REVIEWS (2006)
Endocannabinoid mechanisms of pain modulation
Andrea G. Hohmann et al.
AAPS JOURNAL (2006)
Neuropsychobiological evidence for the functional presence and expression of cannabinoid CB2 receptors in the brain
Emmanuel S. Onaivi
NEUROPSYCHOBIOLOGY (2006)
Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia
JP Despres et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Identification and functional characterization of brainstem cannabinoid CB2 receptors
MD Van Sickle et al.
SCIENCE (2005)
Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli
K Maresz et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Therapeutic opportunities through modulation of the endocannabinoid system
A Makriyannis et al.
NEUROPHARMACOLOGY (2005)
Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
D Osei-Hyiaman et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Cannabinoid-based drugs as anti-inflammatory therapeutics
TW Klein
NATURE REVIEWS IMMUNOLOGY (2005)
Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients:: 1-year experience from the RIO-Europe study
LF Van Gaal et al.
LANCET (2005)
Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice
S Steffens et al.
NATURE (2005)
Antifibrogenic role of the cannabinoid receptor CB2 in the liver
B Julien et al.
GASTROENTEROLOGY (2005)
Prevention of Alzheimer's disease pathology by cannabinoids:: Neuroprotection mediated by blockade of microglial activation
BG Ramírez et al.
JOURNAL OF NEUROSCIENCE (2005)
CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids
MM Ibrahim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Structure and function of fatty acid amide hydrolase
MK McKinney et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2005)
2-arachidonoylglycerol increases in ischemia-reperfusion injury of the rat liver
M Kurabayashi et al.
JOURNAL OF INVESTIGATIVE SURGERY (2005)
The therapeutic potential of drugs that target cannabinoid receptors or modulate the tissue levels or actions of endocannabinoids
RG Pertwee
AAPS JOURNAL (2005)
Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: involvement of cytokine/chemokines and PMN
C Di Filippo et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2004)
Selective activation of cannabinoid CB2 receptors suppresses hyperalgesia evoked by intradermal capsaicin
AG Hohmann et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
The endocannabinoid system and its therapeutic exploitation
V Di Marzo et al.
NATURE REVIEWS DRUG DISCOVERY (2004)
Activation of cannabinoid CB2 receptors suppresses C-fiber responses and windup in spinal wide dynamic range neurons in the absence and presence of inflammation
AG Nackley et al.
JOURNAL OF NEUROPHYSIOLOGY (2004)
Anandamide content is increased and Cb-1 cannabinoid receptor blockade is protective during transient, focal cerebral ischemia
S Muthian et al.
NEUROSCIENCE (2004)
Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia
AH Lichtman et al.
PAIN (2004)
Cannabinoid CB2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naive rats and in rat models of inflammatory and neuropathic pain
SJR Elmes et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension
S Bátkai et al.
CIRCULATION (2004)
Evidence that CB-1 and CB-2 cannabinoid receptors mediate antinociception in neuropathic pain in the rat
DA Scott et al.
PAIN (2004)
Inhibition of inflammatory hyperalgesia by activation of peripheral CB2 cannabinoid receptors
A Quartilho et al.
ANESTHESIOLOGY (2003)
The cannabinoid system and immune modulation
TW Klein et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2003)
Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain:: Pain inhibition by receptors not present in the CNS
MM Ibrahim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Fatty acid amide hydrolase: an emerging therapeutic target in the endocannabinoid system
BF Cravatt et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2003)
Contribution of endocannabinoids in the endothelial protection afforded by ischemic preconditioning in the isolated rat heart
JF Bouchard et al.
LIFE SCIENCES (2003)
Modulation of anxiety through blockade of anandamide hydrolysis
S Kathuria et al.
NATURE MEDICINE (2003)
Selective activation of cannabinoid CB2 receptors suppresses spinal fos protein expression and pain behavior in a rat model of inflammation
AG Nackley et al.
NEUROSCIENCE (2003)
A peripheral cannabinoid mechanism suppresses spinal Fos protein expression and pain behavior in a rat model of inflammation
AG Nackley et al.
NEUROSCIENCE (2003)
The enzymatic inactivation of the fatty acid amide class of signaling lipids
BF Cravatt et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2002)
Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease
RJ McKallip et al.
BLOOD (2002)
International Union of Pharmacology. XXVII. Classification of cannabinoid receptors
AC Howlett et al.
PHARMACOLOGICAL REVIEWS (2002)
CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain
N Clayton et al.
PAIN (2002)
CB2 cannabinoid receptor-mediated peripheral antinociception
TP Malan et al.
PAIN (2001)
Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase
BF Cravatt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Endocannabinoids acting at vascular CB, receptors mediate the vasodilated state in advanced liver cirrhosis
S Bátkai et al.
NATURE MEDICINE (2001)
A historical overview of chemical research on cannabinoids
R Mechoulam et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2000)
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