期刊
FEBS JOURNAL
卷 276, 期 5, 页码 1187-1195出版社
WILEY
DOI: 10.1111/j.1742-4658.2009.06876.x
关键词
chloroplast; dual targeting; inter-organelle communication; mature protein; mitochondria; processing; receptor; regulation; sorting; targeting signal
资金
- Australian Research Council [DP0664692]
As many as fifty proteins have now been experimentally demonstrated to be targeted to both mitochondria and plastids, a phenomenon referred to as dual targeting. Although the first reported case of dual targeting of a protein was reported in 1995, there is still little understanding of the mechanism of dual targeting and any similarities or differences with respect to the targeting of location-specific proteins. This minireview summarizes dual targeting in terms of signals, passenger proteins, receptors, regulation, why proteins may need to be dual targeted and the future challenges that remain in this area.
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