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Genqing Liang et al.
HUMAN MOLECULAR GENETICS (2008)
Polycystin-2 down-regulates cell proliferation via promoting PERK-dependent phosphorylation of eIF2α
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Polycystin-2 cation channel function in the human syncytiotrophoblast is regulated by microtubular structures
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Polycystin-2 cation channel function is under the control of microtubular structures in primary cilia of renal epithelial cells
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Kinesin-2 mediates physical and functional interactions between polycystin-2 and fibrocystin
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HUMAN MOLECULAR GENETICS (2006)
The cells and logic for mammalian sour taste detection
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Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor
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Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells
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JOURNAL OF NEUROCHEMISTRY (2006)
Identification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localization of polycystin-2 in vivo and in vitro
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HUMAN MOLECULAR GENETICS (2006)
Role of the kinesin-2 family protein, KIF3, during mitosis
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
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Polycystin 2 interacts with type I inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor ld2
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Effect of hydro-osmotic pressure on polycystin-2 channel function in the human syncytiotrophoblast
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PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2005)
PKD2 functions as an epidermal growth factor-activated plasma membrane channel
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MOLECULAR AND CELLULAR BIOLOGY (2005)
Cytoskeletal regulation of calcium-permeable cation channels in the human syncytiotrophoblast:: role of gelsolin
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Alpha-actinin associates with polycystin-2 and regulates its channel activity
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HUMAN MOLECULAR GENETICS (2005)
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Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly
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PKD2 interacts and co-localizes with mDia1 to mitotic spindles of dividing cells - Role of mDia1 in PKD2 localization to mitotic spindles
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Troponin I binds polycystin-L and inhibits its calcium-induced channel activation
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Native polycystin 2 functions as a plasma membrane Ca2+-permeable cation channel in renal epithelia
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Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
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Polycystin-2 associates with tropomyosin-1, an actin microfilament component
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JOURNAL OF MOLECULAR BIOLOGY (2003)
Polycystin-2 interacts with troponin I, an angiogenesis inhibitor
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Polycystin-1 activates and stabilizes the polycystin-2 channel
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CD2-associated protein directly interacts with the actin cytoskeleton
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Genetics and pathogenesis of polycystic kidney disease
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JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2002)
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Polycystin-2 is an intracellular calcium release channel
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Polycystin-2 is a novel cation channel implicated in defective intracellular Ca2+ homeostasis in polycystic kidney disease
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Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca2+-permeable nonselective cation channel
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
α-Actinin-2 couples to cardiac Kv1.5 channels, regulating current density and channel localization in HEK cells
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The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)