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FEBS JOURNAL (2008)
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FEBS JOURNAL (2008)
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FEBS JOURNAL (2008)
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Protein-tyrosine phosphatase H1 controls growth hormone receptor signaling and systemic growth
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Neu-mediated phosphorylation of protein tyrosine phosphatase epsilon is critical for activation of Src in mammary tumor cells
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Involvement of protein-tyrosine phosphatase PTPMEG in motor learning and cerebellar long-term depression
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EUROPEAN JOURNAL OF NEUROSCIENCE (2007)
Endocrine regulation of energy metabolism by the skeleton
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CELL (2007)
Protein-tyrosine phosphatase sigma is associated with ulcerative colitis
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CURRENT BIOLOGY (2007)
Leukocyte antigen-related deficiency enhances insulin-like growth factor-1 signaling in vascular smooth muscle cells and promotes neointima formation in response to vascular injury
Xi-Lin Niu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Allelic imbalances and microdeletions affecting the PTPRD gene in cutaneous squamous cell carcinomas detected using single nucleotide polymorphism microarray analysis
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B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity
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IMMUNITY (2007)
How do Shp2 mutations that oppositely influence its biochemical activity result in syndromes with overlapping symptoms?
T. Edouard et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2007)
Methylation and silencing of protein tyrosine phosphatase receptor type O in chronic lymphocytic leukemia
Tasneem Motiwala et al.
CLINICAL CANCER RESEARCH (2007)
Maturational arrest of thymocyte development is caused by a deletion in the receptor-like protein tyrosine phosphatase K gene in LEC rats
Hiroyuki Kose et al.
GENOMICS (2007)
The striatal-enriched protein tyrosine phosphatase gates long-term potentiation and fear memory in the lateral amygdala
Surojit Paul et al.
BIOLOGICAL PSYCHIATRY (2007)
Altered MAP kinase phosphorylation and impaired motor coordination in PTPRR deficient mice
Renato G. S. Chirivi et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Computational design of peptides that target transmembrane helices
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SCIENCE (2007)
Normal TCR signal transduction in mice that lack catalytically active PTPN3 protein tyrosine phosphatase
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JOURNAL OF IMMUNOLOGY (2007)
Protein-tyrosine phosphatase 1B is required for HER2/Neu-induced breast cancer
Mohamed Bentires-Alj et al.
CANCER RESEARCH (2007)
Status epilepticus-induced somatostatinergic hilar interneuron degeneration is regulated by striatal enriched protein tyrosine phosphatase
Yun-Sik Choi et al.
JOURNAL OF NEUROSCIENCE (2007)
Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T
Xiaodong Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Dimerization of protein tyrosine phosphatase σ governs both ligand binding and isoform specificity
Simon Lee et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis
Sofi G. Julien et al.
NATURE GENETICS (2007)
Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis
Melissa G. Dominguez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Protein tyrosine phosphatase function: the substrate perspective
Tony Tiganis et al.
BIOCHEMICAL JOURNAL (2007)
Regulation of signal transducer and activator of transcription signaling by the tyrosine phosphatase PTP-BL
Masakiyo Nakahira et al.
IMMUNITY (2007)
The role of Shp2 (PTPN11) in cancer
M. Golam Mohi et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2007)
Protein tyrosine phosphatase PTPN22 in human autoimmunity
Torkel Vang et al.
AUTOIMMUNITY (2007)
Mutational analysis of PTPRT phosphatase domains in common human cancers
Jong Woo Lee et al.
APMIS (2007)
Essential function of PTP-PEST during mouse embryonic vascularization, mesenchyme formation, neurogenesis and early liver development
Jacinthe Sirois et al.
MECHANISMS OF DEVELOPMENT (2006)
Protein tyrosine phosphatases as negative regulators of the immune response
G. M. Dolton et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2006)
Conditional deletion of Shp2 in the mammary gland leads to impaired lobulo-alveolar outgrowth and attenuated Stat5 activation
Yuehai Ke et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Monoclonal antibody Cat-315 detects a glycoform of receptor protein tyrosine phosphatase beta/phosphacan early in CNS development that localizes to extrasynaptic sites prior to synapse formation
M. R. Dino et al.
NEUROSCIENCE (2006)
Protein tyrosine phosphatases: from genes, to function, to disease
Nicholas K. Tonks
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPρ/PTPRT)
Julie A. Besco et al.
BRAIN RESEARCH (2006)
Noonan syndrome and related disorders: dysregulated RAS-mitogen activated protein kinase signal transduction
Bruce D. Gelb et al.
HUMAN MOLECULAR GENETICS (2006)
Tyrosine phosphatases ε and α perform specific and overlapping functions in regulation of voltage-gated potassium channels in Schwann cells
Zohar Tiran et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
A monoclonal antibody against CD148, a receptor-like tyrosine phosphatase, inhibits endothelial-cell growth and angiogenesis
Takamune Takahashi et al.
BLOOD (2006)
Synaptic plasticity: one STEP at a time
Steven P. Braithwaite et al.
TRENDS IN NEUROSCIENCES (2006)
Reading protein modifications with interaction domains
Bruce T. Seet et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Receptor protein tyrosine phosphatase γ is a marker for pyramidal cells and sensory neurons in the nervous system and is not necessary for normal development
Smaragda Lamprianou et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Altered glucose homeostasis in mice lacking the receptor protein tyrosine phosphatase sigma
Melanie J. Chagnon et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2006)
Protein-tyrosine phosphatase (PTP) wedge domain peptides - A novel approach for inhibition of PTP function and augmentation of protein-tyrosine kinase function
Youmei Xie et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Vascular endothelial cell-specific phosphotyrosine phosphatase (VE-PTP) activity is required for blood vessel development
Sebastian Baeumer et al.
BLOOD (2006)
Protein-tyrosine phosphatase PCP-2 inhibits β-catenin signaling and increases E-cadherin-dependent cell adhesion
He-Xin Yan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Loss of heterozygosity in human aberrant crypt foci (ACF), a putative precursor of colon cancer
Liping Luo et al.
CARCINOGENESIS (2006)
Genetic ablation of Ptprj, a mouse cancer susceptibility gene, results in normal growth and development and does not predispose to spontaneous tumorigenesis
Francesco Trapasso et al.
DNA AND CELL BIOLOGY (2006)
Mammalian motoneuron axon targeting requires receptor protein tyrosine phosphatases σ and δ
Noriko Uetani et al.
JOURNAL OF NEUROSCIENCE (2006)
The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis
Marie-Julie Dubois et al.
NATURE MEDICINE (2006)
High-resolution analysis of chromosomal breakpoints and genomic instability identifies PTPRD as a candidate tumor suppressor gene in neuroblastoma
RL Stallings et al.
CANCER RESEARCH (2006)
Downregulation of the LAR protein tyrosine phosphatase receptor is associated with increased dentate gyrus neurogenesis and an increased number of granule cell layer neurons
R Bernabeu et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2006)
Protein-tyrosine phosphatases and cancer
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NATURE REVIEWS CANCER (2006)
An Shp2/SFK/Ras/Erk signaling pathway controls trophoblast stem cell survival
WT Yang et al.
DEVELOPMENTAL CELL (2006)
Building mammalian signalling pathways with RNAi screens
J Moffat et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Disruption of the transmembrane dense core vesicle proteins IA-2 and IA-2β causes female infertility
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ENDOCRINOLOGY (2006)
Investigations into the regulation and function of the SH2 domain-containing protein-tyrosine phosphatase, SHP-1
Florence W. L. Tsui et al.
IMMUNOLOGIC RESEARCH (2006)
Shp2 is dispensable in the formation and maintenance of the neuromuscular junction
Xian-Ping Dong et al.
NEUROSIGNALS (2006)
Involvement of the small protein tyrosine phosphatases TC-PTP and PTP1B in signal transduction and diseases:: From diabetes, obesity to cell cycle, and cancer
N Dubé et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2005)
Tyrosine phosphatase MEG2 modulates murine development and platelet and lymphocyte activation through secretory vesicle function
YC Wang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Dense core vesicle proteins IA-2 and IA-2β -: Metabolic alterations in double knockout mice
A Kubosaki et al.
DIABETES (2005)
PTPRV is a key mediator of p53-induced cell cycle exit
G Doumont et al.
CELL CYCLE (2005)
The src homology 2 domain-containing tyrosine phosphatase 2 regulates primary T-dependent immune responses and Th cell differentiation
RJ Salmond et al.
JOURNAL OF IMMUNOLOGY (2005)
Identification of an ectodomain within the LAR protein tyrosine phosphatase receptor that binds homophilically and activates signalling pathways promoting neurite outgrowth
T Yang et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Mass spectrometry-based loss of heterozygosity analysis of single-nucleotide polymorphism loci in paraffin embedded tumors assay using the MassEXTEND assay - Single-nucleotide polymorphism loss of heterozygosity analysis of the protein tyrosine phosphatase receptor type J in familial colorectal cancer
M van Puijenbroek et al.
JOURNAL OF MOLECULAR DIAGNOSTICS (2005)
Current issues in mouse genome engineering
S Glaser et al.
NATURE GENETICS (2005)
Genetic ablation of protein tyrosine phosphatase 1B accelerates lymphomagenesis of p53-null mice through the regulation of B-cell development
N Dubé et al.
CANCER RESEARCH (2005)
G1 checkpoint failure and increased tumor susceptibility in mice lacking the novel p53 target Ptprv
G Doumont et al.
EMBO JOURNAL (2005)
Allelic association of the human homologue of the mouse modifier Ptprj with breast cancer
F Lesueur et al.
HUMAN MOLECULAR GENETICS (2005)
Protein tyrosine phosphatase hPTPN20a is targeted to sites of actin polymerization
MT Fodero-Tavoletti et al.
BIOCHEMICAL JOURNAL (2005)
Transmembrane homodimerization of receptor-like protein tyrosine phosphatases
CN Chin et al.
FEBS LETTERS (2005)
Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis
XJ Zhao et al.
CANCER RESEARCH (2005)
Epigenetic profiling of cutaneous T-cell lymphoma:: Promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73
R van Doorn et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Involvement of CD45 in central nervous system myelination
J Nakahara et al.
NEUROSCIENCE LETTERS (2005)
Cytoplasmic protein tyrosine phosphatases, regulation and function:: the roles of PTP1B and TC-PTP
A Bourdeau et al.
CURRENT OPINION IN CELL BIOLOGY (2005)
Receptor protein tyrosine phosphatase sigma inhibits axon regrowth in the adult injured CNS
PS Sapieha et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2005)
Impaired flow-induced dilation in mesenteric resistance arteries from receptor protein tyrosine phosphatase-μ-deficient mice
EA Koop et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2005)
RPTPα is essential for NCAM-mediated p59fyn activation and neurite elongation
V Bodrikov et al.
JOURNAL OF CELL BIOLOGY (2005)
Protein tyrosine phosphatases and the immune response
T Mustelin et al.
NATURE REVIEWS IMMUNOLOGY (2005)
Negative regulation of HER2 signaling by the PEST-type protein-tyrosine phosphatase BDP1
M Gensler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Insulinoma-associated protein IA-2, a vesicle transmembrane protein, genetically interacts with UNC-31/CAPS and affects neurosecretion in Caenorhabditis elegans
T Cai et al.
JOURNAL OF NEUROSCIENCE (2004)
Site-selective regulation of platelet-derived growth factor β receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase
C Persson et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Shp2 regulates Src family kinase activity and Ras/Erk activation by controlling Csk recruitment
SQ Zhang et al.
MOLECULAR CELL (2004)
PEST domain-enriched tyrosine phosphatase (PEP) regulation of effector/memory T cells
K Hasegawa et al.
SCIENCE (2004)
Characterization of multiple transcripts and isoforms derived from the mouse protein tyrosine phosphatase gene Ptprr
RGS Chirivi et al.
GENES TO CELLS (2004)
Mice lacking leukocyte common antigen-related (LAR) protein tyrosine phosphatase domains demonstrate spatial learning impairment in the two-trial water maze and hyperactivity in multiple behavioural tests
MJM Kolkman et al.
BEHAVIOURAL BRAIN RESEARCH (2004)
Mild impairment of motor nerve repair in mice lacking PTP-BL tyrosine phosphatase activity
DG Wansink et al.
PHYSIOLOGICAL GENOMICS (2004)
Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation
T Araki et al.
NATURE MEDICINE (2004)
A novel PTPN11 gene mutation bridges Noonan syndrome, multiple lentigines LEOPARD syndrome and Noonan-like multiple giant cell lesion syndrome
A Sarkozy et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2004)
Targeted disruption of the IA-2β gene causes glucose intolerance and impairs insulin secretion but does not prevent the development of diabetes in NOD mice
A Kubosaki et al.
DIABETES (2004)
Functional significance of the LAR receptor protein tyrosine phosphatase family in development and diseases
MJ Chagnon et al.
BIOCHEMISTRY AND CELL BIOLOGY (2004)
The tyrosine phosphatase PTPRJ/DEP-1 genotype affects thyroid carcinogenesis
R Iuliano et al.
ONCOGENE (2004)
Protein tyrosine phosphatases in the human genome
A Alonso et al.
CELL (2004)
Tyrosine phosphatase epsilon is a positive regulator of osteoclast function in vitro and in vivo
R Chiusaroli et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
A genomic perspective on protein tyrosine phosphatases: gene structure, pseudogenes, and genetic disease linkage
JN Andersen et al.
FASEB JOURNAL (2004)
Mutational analysis of the tyrosine phosphatome in colorectal cancers
ZH Wang et al.
SCIENCE (2004)
Potential role of protein tyrosine phosphatase nonreceptor type 13 in the control of oocyte meiotic maturation
T Nedachi et al.
DEVELOPMENT (2004)
Protein tyrosine phosphatase alpha (PTPα) knockout mice show deficits in Morris water maze learning, decreased locomotor activity, and decreases in anxiety
MR Skelton et al.
BRAIN RESEARCH (2003)
Receptor protein tyrosine phosphatase α is essential for hippocampal neuronal migration and long-term potentiation
A Petrone et al.
EMBO JOURNAL (2003)
Receptor protein tyrosine phosphatase sigma inhibits axonal regeneration and the rate of axon extension
KM Thompson et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2003)
PTPRQ is a novel phosphatidylinositol phosphatase that can be expressed as a cytoplasmic protein or as a subcellularly localized receptor-like protein
RA Seifert et al.
EXPERIMENTAL CELL RESEARCH (2003)
Protein tyrosine phosphatase RQ is a phosphatidylinositol phosphatase that can regulate cell survival and proliferation
A Oganesian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling
BG Neel et al.
TRENDS IN BIOCHEMICAL SCIENCES (2003)
LOH of PTPRJ occurs early in colorectal cancer and is associated with chromosomal loss of 18q12-21
C Ruivenkamp et al.
ONCOGENE (2003)
Tyrosine phosphatase-ε activates Src and supports the transformed phenotype of Neu-induced mammary tumor cells
H Gil-Henn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Protein tyrosine phosphatases: the quest for negative regulators of insulin action
E Asante-Appiah et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2003)
The function of the protein tyrosine phosphatase SHP-1 in cancer
CY Wu et al.
GENE (2003)
A mutant receptor tyrosine phosphatase, CD148, causes defects in vascular development
T Takahashi et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori
A Fujikawa et al.
NATURE GENETICS (2003)
Multimerization of the protein-tyrosine phosphatase (PTP)-like insulin-dependent diabetes mellitus autoantigens IA-2 and IA-2β with receptor PTPs (RPTPs) -: Inhibition of RPTPα enzymatic activity
S Gross et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
A critical role for the protein tyrosine phosphatase receptor type Z in functional recovery from demyelinating lesions
S Harroch et al.
NATURE GENETICS (2002)
Protein tyrosine phosphatase σ-deficient mice show aberrant cytoarchitecture and structural abnormalities in the central nervous system
K Meathrel et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers
CAL Ruivenkamp et al.
NATURE GENETICS (2002)
Targeted disruption of the protein tyrosine phosphatase-like molecule IA-2 results in alterations in glucose tolerance tests and insulin secretion
K Saeki et al.
DIABETES (2002)
Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder
CA Wise et al.
HUMAN MOLECULAR GENETICS (2002)
Pituitary, pancreatic and gut neuroendocrine defects in protein tyrosine phosphatase-sigma-deficient mice
J Batt et al.
MOLECULAR ENDOCRINOLOGY (2002)
Structural and evolutionary relationships among protein tyrosine phosphatase domains
JN Andersen et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Hematopoietic protein tyrosine phosphatase suppresses extracellular stimulus-regulated kinase activation
M Gronda et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Functional abnormalities in protein tyrosine phosphatase ε-deficient macrophages
V Sully et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Dephosphorylation of β2-syntrophin and Ca2+/μ-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretion
T Ort et al.
EMBO JOURNAL (2001)
Inhibition of cell growth and spreading by stomach cancer-associated protein-tyrosine phosphatase-1 (SAP-1) through dephosphorylation of p130cas
T Noguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Protein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinases
HY Jui et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity
R Majeti et al.
CELL (2000)
HD-PTP: A novel protein tyrosine phosphatase gene on human chromosome 3p21.3
S Toyooka et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate
BL Wharram et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
No obvious abnormality in mice deficient in receptor protein tyrosine phosphatase β
S Harroch et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Hypomyelination and increased activity of voltage-gated K+ channels in mice lacking protein tyrosine phosphatase ε
A Peretz et al.
EMBO JOURNAL (2000)
The CD45 tyrosine phosphatase: a positive and negative regulator of immune cell function
DR Alexander
SEMINARS IN IMMUNOLOGY (2000)
Impaired learning with enhanced hippocampal long-term potentiation in PTPδ-deficient mice
N Uetani et al.
EMBO JOURNAL (2000)
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