相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model
Heng Du et al.
NEUROBIOLOGY OF AGING (2011)
RAGE regulates BACE1 and Aβ generation via NFAT1 activation in Alzheimer's disease animal model
H. J. Cho et al.
FASEB JOURNAL (2009)
A beta-Dependent Inhibition of LTP in Different Intracortical Circuits of the Visual Cortex: The Role of RAGE
Nicola Origlia et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
Hippocampal RAGE immunoreactivity in early and advanced Alzheimer's disease
Miles C. Miller et al.
BRAIN RESEARCH (2008)
Site-specific blockade of RAGE-Vd prevents amyloid-β oligomer neurotoxicity
Emmanuel Sturchler et al.
JOURNAL OF NEUROSCIENCE (2008)
Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-β-mediated cortical synaptic dysfunction
Nicola Origlia et al.
JOURNAL OF NEUROSCIENCE (2008)
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
Heng Du et al.
NATURE MEDICINE (2008)
Novel p38α MAPK inhibitor suppresses brain proinflammatory cytokine up-regulation and attenuates synaptic dysfunction and behavioral deficits in an Alzheimer's disease mouse model
Lenka Munoz et al.
JOURNAL OF NEUROINFLAMMATION (2007)
Microglia repetitively isolated from in vitro mixed glial cultures retain their initial phenotype
A. M. Floden et al.
JOURNAL OF NEUROSCIENCE METHODS (2007)
Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
Joseph El Khoury et al.
NATURE MEDICINE (2007)
Interferon-γ and tumor necrosis factor-a regulate amyloid-α plaque deposition and β-secretase expression in Swedish mutant APP transgenic mice
Masaru Yamamoto et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Cytotoxicity of A beta(1-42), RAGE(23-54), and an A beta-RAGE complex in PC-12 cells
Shyamala Mruthinti et al.
CURRENT ALZHEIMER RESEARCH (2007)
Deficiency in neuronal TGF-β signaling promotes neurodegeneratbn and Alzheimer's pathology
Ina Tesseur et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
The induction of surface β-amyloid binding proteins and enhanced cytotoxicity in cultured PC-12 and IMR-32 cells by advanced glycation end products
S. Mruthinti et al.
NEUROSCIENCE (2006)
Interleukin-1 mediates Alzheimer and Lewy body pathologies
W. Sue T. Griffin et al.
JOURNAL OF NEUROINFLAMMATION (2006)
Glia as a therapeutic target:: Selective suppression of human amyloid-β-induced upregulation of brain proinflammatory cytokine production attenuates neurodegeneration
HR Ranaivo et al.
JOURNAL OF NEUROSCIENCE (2006)
Harnessing the power of gene microarrays for the study of brain aging and Alzheimer's disease: Statistical reliability and functional correlation
EM Blalock et al.
AGEING RESEARCH REVIEWS (2005)
Investigations with cultured human microglia on pathogenic mechanisms of Alzheimer's disease and other neurodegenerative diseases
DG Walker et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2005)
P38 activation mediates amyloid-β cytotoxicity
XW Zhu et al.
NEUROCHEMICAL RESEARCH (2005)
Mitochondrial dysfunction and Alzheimer's disease:: role of amyloid-β peptide alcohol dehydrogenase (ABAD)
SD Yan et al.
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (2005)
Role of inflammation in neurodegenerative diseases
L Minghetti
CURRENT OPINION IN NEUROLOGY (2005)
Acute treatment with the PPARγ agonist pioglitazone and ibuprofen reduces glial inflammation and Aβ1-42 levels in APPV717I transgenic mice
MT Heneka et al.
BRAIN (2005)
Overexpression of monocyte chemotactic protein-1/CCL2 in β-amyloid precursor protein transgenic mice show accelerated diffuse β-amyloid deposition
M Yamamoto et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Transgenic AD model mice, effects of potential anti-AD treatments on inflammation and pathology
T van Groen et al.
BRAIN RESEARCH REVIEWS (2005)
β-Amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor α and NMDA receptors
AM Floden et al.
JOURNAL OF NEUROSCIENCE (2005)
ABAD enhances A beta-induced cell stress via mitochondrial dysfunction
K Takuma et al.
FASEB JOURNAL (2005)
Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice
Michael T. Heneka et al.
JOURNAL OF NEUROINFLAMMATION (2005)
Interleukin 1 receptor antagonist knockout mice show enhanced microglial activation and neuronal damage induced by intracerebroventricular infusion of human beta-amyloid
Jeffrey M. Craft et al.
JOURNAL OF NEUROINFLAMMATION (2005)
Preventing Activation of Receptor for Advanced Glycation Endproducts in Alzheimer's Disease
L-F Lue et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2005)
The biology of p38 kinase: A central role in inflammation
GL Schieven
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2005)
Dynamic complexity of the microglial activation response in transgenic models of amyloid deposition: Implications for Alzheimer therapeutics
D Morgan et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2005)
ABAD directly links Aβ to mitochondrial toxicity in Alzheimer's disease
JW Lustbader et al.
SCIENCE (2004)
Overexpression of receptor of advanced glycation end products hypersensitizes cells for amyloid beta peptide-induced cell death
A Hadding et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2004)
Autoimmunity in Alzheimer's disease:: increased levels of circulating IgGs binding Aβ and RAGE peptides
S Mruthinti et al.
NEUROBIOLOGY OF AGING (2004)
Inflammation occurs early during the Aβ deposition process in TgCRND8 mice
S Dudal et al.
NEUROBIOLOGY OF AGING (2004)
RAGE modulates peripheral nerve regeneration via recruitment of both inflammatory and axonal outgrowth pathways
LL Rong et al.
FASEB JOURNAL (2004)
Tumor necrosis factor-α, interleukin-1β, and interferon-γ stimulate γ-secretase-mediated cleavage of amyloid precursor protein through a JNK-dependent MAPK pathway
YF Liao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
RAGE potentiates Aβ-induced perturbation of neuronal function in transgenic mice
O Arancio et al.
EMBO JOURNAL (2004)
Stress kinases involved in tau phosphorylation in Alzheimer's disease, tauopathies and APP transgenic mice
I Ferrer
NEUROTOXICITY RESEARCH (2004)
Increased MAP kinase activity in Alzheimer's and Down syndrome but not in schizophrenia human brain
JE Swatton et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
p38 Kinase Is Activated in the Alzheimer's Disease Brain
Kenneth Hensley et al.
JOURNAL OF NEUROCHEMISTRY (2003)
p38 MAP kinase is activated at early stages in Alzheimer's disease brain
AY Sun et al.
EXPERIMENTAL NEUROLOGY (2003)
Intrathecal inflammation precedes development of Alzheimer's disease
E Tarkowski et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2003)
RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain
R Deane et al.
NATURE MEDICINE (2003)
Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo
W Farris et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Immune reactive cells in senile plaques and cognitive decline in Alzheimer's disease
AK Vehmas et al.
NEUROBIOLOGY OF AGING (2003)
Relationship between the induction of RAGE cell-surface antigen and the expression of amyloid binding sites
S Mruthinti et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2003)
Modeling Alzheimer's disease immune therapy mechanisms: Interactions of human postmortem microglia with antibody-opsonized amyloid beta peptide
LF Lue et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
β-amyloid-induced inflammation and cholinergic hypofunction in the rat brain in vivo:: Involvement of the p38MAPK pathway
MG Giovannini et al.
NEUROBIOLOGY OF DISEASE (2002)
Effect of endothelial cell polarity on β-amyloid-induced migration of monocytes across normal and AD endothelium
R Giri et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2002)
Activation of MKK6, an upstream activator of p38, in Alzheimer's disease
XW Zhu et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Modeling microglial activation in Alzheimer's disease with human postmortem microglial cultures
LF Lue et al.
NEUROBIOLOGY OF AGING (2001)
Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: Identification of a cellular activation mechanism
LF Lue et al.
EXPERIMENTAL NEUROLOGY (2001)
Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer's disease
N Sasaki et al.
BRAIN RESEARCH (2001)
Localization of active forms of C-jun kinase (JNK) and p38 kinase in Alzheimer's disease brains at different stages of neurofibrillary degeneration
Jin-Jing Pei et al.
JOURNAL OF ALZHEIMERS DISEASE (2001)
β-Amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1
R Giri et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2000)
Inflammation and Alzheimer's disease
H Akiyama et al.
NEUROBIOLOGY OF AGING (2000)
Protection of hearts from reperfusion injury by propofol is associated with inhibition of the mitochondrial permeability transition
SA Javadov et al.
CARDIOVASCULAR RESEARCH (2000)