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Lydie Viatte et al.
BIOCHIMIE (2009)
Contribution of STAT3 and SMAD4 pathways to the regulation of hepcidin by opposing stimuli
Hua Huang et al.
BLOOD (2009)
BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression
Leon Kautz et al.
BLOOD (2009)
Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells
Toshihiko Tanno et al.
BLOOD (2009)
Toll-like receptors mediate induction of hepcidin in mice infected with Borrelia burgdorferi
Curry L. Koening et al.
BLOOD (2009)
Interaction of the Hereditary Hemochromatosis Protein HFE with Transferrin Receptor 2 Is Required for Transferrin-Induced Hepcidin Expression
Junwei Gao et al.
CELL METABOLISM (2009)
A Ferroportin Transcript that Lacks an Iron-Responsive Element Enables Duodenal and Erythroid Precursor Cells to Evade Translational Repression
De-Liang Zhang et al.
CELL METABOLISM (2009)
Matriptase-2 (TMPRSS6): a proteolytic regulator of iron homeostasis
Andrew J. Ramsay et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2009)
Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes
Guillemette Ramey et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2009)
Activated macrophages induce hepcidin expression in HuH7 hepatoma cells
Pavle Matak et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2009)
Combined Deletion of Hfe and Transferrin Receptor 2 in Mice Leads to Marked Dysregulation of Hepcidin and Iron Overload
Daniel F. Wallace et al.
HEPATOLOGY (2009)
Circulating Hepcidin in the Crossroads of Anemia and Inflammation Associated with Rheumatoid Arthritis
Mehmet Derya Demirag et al.
INTERNAL MEDICINE (2009)
Oncostatin M and leukemia inhibitory factor increase hepcidin expression in hepatoma cell lines
Junya Kanda et al.
INTERNATIONAL JOURNAL OF HEMATOLOGY (2009)
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
Delphine Meynard et al.
NATURE GENETICS (2009)
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
Billy Andriopoulos et al.
NATURE GENETICS (2009)
Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver
Leon Kautz et al.
BLOOD (2008)
The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression
Paul J. Schmidt et al.
CELL METABOLISM (2008)
Regulation of iron acquisition and storage: consequences for iron-linked disorders
Ivana De Domenico et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Autocrine formation of hepcidin induces iron retention in human monocytes
Igor Theurl et al.
BLOOD (2008)
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
Paul B. Yui et al.
NATURE CHEMICAL BIOLOGY (2008)
Expression and localization of hepcidin in macrophages: a role in host defense against tuberculosis
Fatoumata B. Sow et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin
Toshihiko Tanno et al.
NATURE MEDICINE (2007)
Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance
Jodie L. Babitt et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Iron overload in Hepc1-/- mice is not impairing glucose homeostasis
G. Ramey et al.
FEBS LETTERS (2007)
STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo
Antonello Pietrangelo et al.
GASTROENTEROLOGY (2007)
STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation
Maria Vittoria Verga Falzacappa et al.
BLOOD (2007)
Suppression of hepcidin during anemia requires erythropoietic activity
Mihwa Pak et al.
BLOOD (2006)
Interleukin induces hepcidin expression through STAT3
Diedra M. Wrighting et al.
BLOOD (2006)
Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing
Tapasree Goswami et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens
C Peyssonnaux et al.
BLOOD (2006)
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
JL Babitt et al.
NATURE GENETICS (2006)
Signals for stress erythropoiesis are integrated via an erythropoietin receptor-phosphotyrosine-343-Stat5 axis
MP Menon et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
A role of SMAD4 in iron metabolism through the positive regulation of hepicidin expression
RH Wang et al.
CELL METABOLISM (2005)
Upregulation of hepcidin by interleukin-1β in human hepatoma cell lines
J Inamura et al.
HEPATOLOGY RESEARCH (2005)
Iron- and inflammation-induced hepcidin gene expression in mice is not mediated by Kupffer cells in vivo
DQ Lou et al.
HEPATOLOGY (2005)
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis
A Donovan et al.
CELL METABOLISM (2005)
Regulation of hepcidin transcription by interleukin-1 and interleukin-6
P Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Oncostatin M: a pleiotropic cytokine in the central nervous system
SH Chen et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2004)
Regulation of transferrin receptor 2 protein levels by transferrin
A Robb et al.
BLOOD (2004)
Diferric transferrin regulates transferrin receptor 2 protein stability
MB Johnson et al.
BLOOD (2004)
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
E Nemeth et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
PC Heinrich et al.
BIOCHEMICAL JOURNAL (2003)
Severe iron deficiency anemia in transgenic mice expressing liver hepcidin
G Nicolas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
CH Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
C Pigeon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Oncostatin M and hepatocyte growth factor induce hepatic maturation via distinct signaling pathways
A Kamiya et al.
FEBS LETTERS (2001)
Proteasomes regulate the duration of erythropoietin receptor activation by controlling down-regulation of cell surface receptors
F Verdier et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)