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Rudy J. Castellani et al.
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Silvia Mandel et al.
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Dong Fu et al.
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Karl Herrup et al.
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Kevin H. J. Park et al.
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Christian Haass et al.
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Bim is elevated in Alzheimer's disease neurons and is required for β-amyloid-induced neuronal apoptosis
Subhas C. Biswas et al.
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Yael Avramovich-Tirosh et al.
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Qiang Liu et al.
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Jack Woods et al.
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Xiongwei Zhu et al.
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Agata Copani et al.
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Thomas Arendt et al.
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High-throughput drug screen targeted to the 5′ untranslated region of Alzheimer amyloid precursor protein mRNA
Sanghamitra Bandyopadhyay et al.
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L Reznichenko et al.
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L Pastorino et al.
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N Khan et al.
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Green tea catechins as brain-permeable, natural iron chelators-antioxidants for the treatment of neurodegenerative disorders
S Mandel et al.
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Ectopic cell cycle events link human Alzheimer's disease and amyloid precursor protein transgenic mouse models
Y Yang et al.
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Hypoxia-inducible factor prolyl 4-hydroxylase inhibition - A target for neuroprotection in the central nervous system
A Siddiq et al.
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DS Kalinowski et al.
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Novel multifunctional neuroprotective iron chelator-monoamine oxidase inhibitor drugs for neurodegenerative diseases:: in vitro studies on antioxidant activity, prevention of lipid peroxide formation and monoamine oxidase inhibition
H Zheng et al.
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KM Webber et al.
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Novel multifunctional neuroprotective iron chelator-monoamine oxidase inhibitor drugs for neurodegenerative diseases. In vivo selective brain monoamine oxidase inhibition and prevention of MPTP-induced striatal dopamine depletion
S Gal et al.
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K Rezai-Zadeh et al.
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The last neuronal division: a unifying hypothesis for the pathogenesis of Alzheimer's disease
Z Nagy
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Oxidative stress mechanisms and potential therapeutics in Alzheimer disease
PI Moreira et al.
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Cell cycle inhibition provides neuroprotection and reduces glial proliferation and scar formation after traumatic brain injury
S Di Giovanni et al.
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Green tea polyphenol (-)-epigallocatechin-3-gallate induces neurorescue of long-term serum-deprived PC12 cells and promotes neurite outgrowth
L Reznichenko et al.
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CH Kim et al.
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FS Yang et al.
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HL Zheng et al.
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Multifunctional activities of green tea catechins in neuroprotection - Modulation of cell survival genes, iron-dependent oxidative stress and PKC signaling pathway
SA Mandel et al.
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D Ben Shachar et al.
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JT Rogers et al.
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Novel neuronal targets for the acetylcholinesterase inhibitor donepezil
MA Sortino et al.
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L Zecca et al.
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A Dedeoglu et al.
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Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro:: implications for the prevention and therapeutics of Alzheimer's disease
K Ono et al.
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CS Atwood et al.
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YC Liou et al.
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DB Lovejoy et al.
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AI Bush
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L Korhonen et al.
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Y Levites et al.
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JA Klein et al.
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S Gupta et al.
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RW Shin et al.
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CW Ritchie et al.
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S Payton et al.
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An iron-responsive element type II in the 5′-untranslated region of the Alzheimer's amyloid precursor protein transcript
JT Rogers et al.
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NTV Le et al.
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Erratic expression of DNA polymerases by β-amyloid causes neuronal death
A Copani et al.
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Kainic acid-induced apoptosis in cerebellar granule neurons:: an attempt at cell cycle re-entry
E Verdaguer et al.
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A Copani et al.
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Robert Bowser et al.
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Y Levites et al.
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RA Cherny et al.
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S Leclerc et al.
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XW Zhu et al.
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