期刊
FARADAY DISCUSSIONS
卷 149, 期 -, 页码 171-185出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c005374k
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资金
- NATIONAL INSTITUTE ON DRUG ABUSE [R21DA026980] Funding Source: NIH RePORTER
- NIDA NIH HHS [R21 DA026980, R21 DA026980-01] Funding Source: Medline
Due to their ability to serve as fluorophores and drug delivery vehicles, quantum dots are a powerful tool for theranostics-based clinical applications. In this study, microneedle devices for transdermal drug delivery were fabricated by means of two-photon polymerization of an acrylate-based polymer. We examined proliferation of cells on this polymer using neonatal human epidermal keratinocytes and human dermal fibroblasts. The microneedle device was used to inject quantum dots into porcine skin; imaging of the quantum dots was performed using multiphoton microscopy.
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