Clinical complications of Densiron 68 intraocular tamponade for complicated retinal detachment

Purpose To report and disscuss the postoperative complications in patients after Densiron 68 intraocular tamponade in the management of complicated retinal detachment with proliferative vitreoretinopathy (PVR). Methods We presented a prospective interventional non-comparative case series of 27 eyes of 27 consecutive patients. Inclusion criteria were PVR, posterior or inferior retinal breaks, and the patient's inability to posture. Vitreoretinal surgery with Densiron 68 intraocular tamponade was performed in all patients. Complications were recorded at 1 week and 1, 2, and 3 months after Densiron 68 intraocular tamponade and after removal of Densiron 68 endotamponade at same periods. Results The most common complication was posterior capsule opacification and cataract development in seven eyes (25.9%) and in two eyes (25%, 2/8), respectively, the second complication was intraocular inflammation in six eyes (22.2%), the third complication was emulsification and dispersion and raised intraocular pressure in five eyes (18.5%), respectively. The success rate with one operation using Densiron 68 was 85.2% and with further surgery 92.5%. Visual acuity improved from mean logMAR of 2.12 (SD = 0.68) to 1.16 (SD = 0.84), P = 0.0001. Conclusions According to the results of this study, postoperative complications did not increase significantly in the vitreoretinal surgery with temporary Densiron 68 intraocular tamponade. Densiron 68 intraocular tamponade is safe and effective in treating complicated retinal detachment. Eye (2010) 24, 21-28; doi: 10.1038/eye.2009.57; published online 27 March 2009