期刊
EXPERT REVIEW OF VACCINES
卷 10, 期 5, 页码 575-588出版社
TAYLOR & FRANCIS LTD
DOI: 10.1586/ERV.11.32
关键词
meningococcal vaccines; Neisseria meningitidis; outer membrane vesicle; recombinant proteins serogroup B
类别
资金
- Novartis Vaccines
- Oxford Partnership Comprehensive Biomedical Research Centre
- NIHR Biomedical Research Centre
Although meningococcal disease caused by serogroup B remains an important public health concern, a licensed vaccine providing broad protection against this pathogen is not yet available. Advances in genomics have paved the way for the discovery of new vaccine candidates for inclusion into a multicomponent serogroup B vaccine. In this article, we will review recent advances in the development of these vaccines, focussing particularly on one of the 'next generation' MenB vaccines, 4CMenB.
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