相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Truncation of Tau Protein and its Pathological Significance in Alzheimer's Disease
Francisco García-Sierra et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Prion protein amyloidosis with divergent phenotype associated with two novel nonsense mutations in PRNP
Casper Jansen et al.
ACTA NEUROPATHOLOGICA (2010)
A Single Mutation at the Sheet Switch Region Results in Conformational Changes Favoring λ6 Light-Chain Fibrillogenesis
Alejandra Hernandez-Santoyo et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
The Neuronal Expression of MYC Causes a Neurodegenerative Phenotype in a Novel Transgenic Mouse
Hyoung-Gon Lee et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Overexpression of Mitochondrial Ferritin Sensitizes Cells to Oxidative Stress Via an Iron-Mediated Mechanism
Zhongbing Lu et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
Promising Strategies for the Prevention of Dementia
Laura E. Middleton et al.
ARCHIVES OF NEUROLOGY (2009)
Differential interaction and aggregation of 3-repeat and 4-repeat tau isoforms with 14-3-3ζ protein
Golam Sadik et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Ellagic acid promotes Aβ42 fibrillization and inhibits Aβ42-induced neurotoxicity
Ying Feng et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Conformational Changes Specific for Pseudophosphorylation at Serine 262 Selectively Impair Binding of Tau to Microtubules
Daniela Fischer et al.
BIOCHEMISTRY (2009)
Response to the increase of oxidative stress and mutation of mitochondrial DNA in aging
Yi-Shing Ma et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2009)
New Age of Neuroproteomics in Alzheimer's Disease Research
Branislav Kovacech et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2009)
Alternative Aβ Immunotherapy Approaches for Alzheimer's Disease
Terrence Town
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2009)
Understanding the Basis for the Association of apoE4 with Alzheimer's Disease: Opening the Door for Therapeutic Approaches
Ning Zhong et al.
CURRENT ALZHEIMER RESEARCH (2009)
Genetic Interaction between Tau and the Apolipoprotein E Receptor LRP1 Increases Alzheimer's Disease Risk
Jose Luis Vazquez-Higuera et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2009)
Epigenetics, oxidative stress, and Alzheimer disease
Nasser H. Zawia et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
Watching the watcher: regulation of p53 by mitochondria
Aaron K. Holley et al.
FUTURE ONCOLOGY (2009)
DNA β-Amyloid1-42 Trimer Immunization for Alzheimer Disease in a Wild-Type Mouse Model
Doris Lambracht-Washington et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)
Mitochondria, cholesterol and amyloid β peptide: a dangerous trio in Alzheimer disease
Anna Colell et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2009)
Behavioral stress accelerates plaque pathogenesis in the brain of Tg2576 mice via generation of metabolic oxidative stress
Kang-Woo Lee et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Aβ Immunotherapy: Intracerebral Sequestration of Aβ by an Anti-Aβ Monoclonal Antibody 266 with High Affinity to Soluble Aβ
Kaoru Yamada et al.
JOURNAL OF NEUROSCIENCE (2009)
Amyloid β-Induced Neuronal Hyperexcitability Triggers Progressive Epilepsy
Rimante Minkeviciene et al.
JOURNAL OF NEUROSCIENCE (2009)
Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers
Juha Lauren et al.
NATURE (2009)
Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy
Guojun Bu
NATURE REVIEWS NEUROSCIENCE (2009)
A Recessive Mutation in the APP Gene with Dominant-Negative Effect on Amyloidogenesis
Giuseppe Di Fede et al.
SCIENCE (2009)
Aβ31-35-induced neuronal apoptosis is mediated by JNK-dependent extrinsic apoptosis pathway
Ling-Min Li et al.
NEUROSCIENCE BULLETIN (2009)
Genetics of Alzheimer's disease: recent advances
Dimitrios Avramopoulos
GENOME MEDICINE (2009)
Early-onset Alzheimer disease in an Italian family with presenilin-1 double mutation E318G and G394V
Sara Batelli et al.
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2008)
Molecular genetics of Alzheimer's disease: An update
Nathalie Brouwers et al.
ANNALS OF MEDICINE (2008)
Presenilin 1 Polymorphism Associated with Alzheimer's Disease in Apolipoprotein E4 Carriers
Ana Martinez-Garcia et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2008)
A novel presenilin 2 mutation (V393M) in early-onset dementia with profound language impairment
S. G. Lindquist et al.
EUROPEAN JOURNAL OF NEUROLOGY (2008)
Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease
Siddhartha Mondragon-Rodriguez et al.
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (2008)
Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2 in cortical neurons
Phullara B. Shelat et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
Ganesh M. Shankar et al.
NATURE MEDICINE (2008)
Oxidatively modified RNA in mild cognitive impairment
Mark A. Lovell et al.
NEUROBIOLOGY OF DISEASE (2008)
Amyloid-β in Alzheimer disease:: The null versus the alternate hypotheses
Hyoung-gon Lee et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Aβ oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine
Fernanda G. De Felice et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
A beta, tau and ApoE4 in Alzheimer's disease: the axonal connect ion
Robert Adalbert et al.
TRENDS IN MOLECULAR MEDICINE (2007)
The cell cycle hypothesis of Alzheimer's disease: Suggestions for drug development
Jack Woods et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2007)
Oxidative RNA damage and neurodegeneration
A. Nunomura et al.
CURRENT MEDICINAL CHEMISTRY (2007)
Site-specific phosphorylation and caspase cleavage differentially impact tau-microtubule interactions and tau aggregation
Huiping Ding et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Truncated tau from sporadic Alzheimer's disease suffices to drive neurofibrillary degeneration in vivo
Norbert Zilka et al.
FEBS LETTERS (2006)
Tau phosphorylation and aggregation in Alzheimer's disease pathology
J Avila
FEBS LETTERS (2006)
Covariate analysis of late-onset Alzheimer disease refines the chromosome 12 locus
X Liang et al.
MOLECULAR PSYCHIATRY (2006)
The cell cycle in Alzheimer disease: A unique target for neuropharmacology
KM Webber et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2005)
Hippocampal metabolic abnormalities in mild cognitive impairment and Alzheimer's disease
N Ackl et al.
NEUROSCIENCE LETTERS (2005)
Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease
AL Guillozet-Bongaarts et al.
NEUROBIOLOGY OF AGING (2005)
Amyloid-β in Alzheimer's disease:: the horse or the cart?: Pathogenic or protective?
HG Lee et al.
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (2005)
Mitogen- and stress-activated protein kinase 1: Convergence of the ERK and p38 pathways in Alzheimer's disease
KM Webber et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2005)
The apolipoprotein E ε4 allele and incident Alzheimer's disease in persons with mild cognitive impairment
NT Aggarwal et al.
NEUROCASE (2005)
Conformational transition state is responsible for assembly of microtubule-binding domain of tau protein
S Hiraoka et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Detection of oxidative DNA damage in lymphocytes of patients with Alzheimer's disease
E Kadioglu et al.
BIOMARKERS (2004)
Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease
A Nunomura et al.
NEUROBIOLOGY OF DISEASE (2004)
Alzheimer's missing link?
[Anonymous]
MOLECULAR THERAPY (2003)
Cerebrometabolic abnormalities in Alzheimer's disease
JP Blass
NEUROLOGICAL RESEARCH (2003)
Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease
TC Gamblin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
H2O2 and 4-hydroxynonenal mediate amyloid β-induced neuronal apoptosis by activating JNKs and p38MAPK
E Tamagno et al.
EXPERIMENTAL NEUROLOGY (2003)
Up-regulation of cDK5/p35 by oxidative stress in human neuroblastoma IMR-32 cells
P Strocchi et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2003)
Mutations in presenilin 1, presenilin 2 and amyloid precursor protein genes in patients with early-onset Alzheimer's disease in Poland
C Zekanowski et al.
EXPERIMENTAL NEUROLOGY (2003)
Tau conformational changes correspond to impairments of episodic memory in mild cognitive impairment and Alzheimer's disease
N Ghoshal et al.
EXPERIMENTAL NEUROLOGY (2002)
Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
J Hardy et al.
SCIENCE (2002)
Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease
JC Augustinack et al.
ACTA NEUROPATHOLOGICA (2002)
Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis
XW Zhu et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2001)
Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments
AD Alonso et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Cerebral blood flow and metabolic abnormalities in Alzheimer's disease
H Matsuda
ANNALS OF NUCLEAR MEDICINE (2001)
Increased production of β-amyloid and vulnerability to endoplasmic reticulum stress by an aberrant spliced form of presenilin 2
N Sato et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Activation and redistribution of c-Jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease
XW Zhu et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Activation of oncogenic pathways in degenerating neurons in Alzheimer disease
XW Zhu et al.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE (2000)
APOE promoter polymorphisms do not confer independent risk for Alzheimer's disease in a French population
L Zurutuza et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2000)
Metabolic, Metallic, and Mitotic Sources of Oxidative Stress in Alzheimer Disease
Mark A. Smith et al.
ANTIOXIDANTS & REDOX SIGNALING (2000)
分享论文
