期刊
EXPERT REVIEW OF NEUROTHERAPEUTICS
卷 9, 期 4, 页码 535-539出版社
TAYLOR & FRANCIS LTD
DOI: 10.1586/ERN.09.4
关键词
astrocytoma; brainstem glioma; brain tumor; optic glioma; pilocytic astrocytoma
Neurofibromatosis type 1 (NF1) is an inherited autosomal dominant disorder characterized by numerous cutaneous features, including cafe-au-lait macules, skinfold freckling and iris hamartomas. In addition, individuals with NF1 are prone to the development of both benign and malignant tumors. The most common CNS tumor in children and adults with NF1 is the glioma. In childhood, gliomas are primarily located in the optic pathway, and less frequently in the hypothalamus and brainstem. Regular ophthalmologic evaluations in children are essential for the effective management of these tumors in patients with NF1. Adults, in contrast, are more likely to develop higher grade gliomas, which are treated in a similar fashion as their sporadic counterparts.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据