期刊
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
卷 11, 期 7, 页码 711-720出版社
EXPERT REVIEWS
DOI: 10.1586/ERM.11.59
关键词
clinical assays; diagnostics; heterogeneous immunoassays; magnetic particles; microfluidics; particles; surface-based
类别
资金
- Engineering and Physical Sciences Research Council in the UK
The need for fast, specific and portable diagnostic systems for clinical assays has, in recent years, led to an explosion of research into microfluidic chip-based immunoassays towards rapid point-of-care analysis. Such devices exploit small dimensions, superior fluidic control and low reagent volumes to allow a number of clinically important procedures to be achieved with improvements on conventional methods, many of which rely on the surface-based binding of antigens to antibodies. Here, we discuss recent developments and innovations in the area of on-chip surface-based immunoassays and provide an outlook on the potential of such platforms for future diagnostics.
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