4.3 Review

An update on leptin as immunomodulator

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Leptin Modulates Allograft Survival by Favoring a Th2 and a Regulatory Immune Profile

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Leptin modulates dose-dependently the metabolic and cytolytic activities of NK-92 cells

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Leptin up-regulates TLR2 in human monocytes

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Leptin Inhibits Neutrophil Apoptosis in Children via ERK/NF-κB-Dependent Pathways

Zhizhi Sun et al.

PLOS ONE (2013)

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Selective capacity of metreleptin administration to reconstitute CD4+ T-cell number in females with acquired hypoleptinemia

Giuseppe Matarese et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Biochemistry & Molecular Biology

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MOLECULAR ASPECTS OF MEDICINE (2012)

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Leptin: A Critical Regulator of CD4(+) T-cell Polarization in Vitro and in Vivo

Arvind Batra et al.

ENDOCRINOLOGY (2010)

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Javier Conde et al.

EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2010)

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Molecular mechanism underlying the inflammatory complication of leptin in macrophages

Tamisha Vaughan et al.

MOLECULAR IMMUNOLOGY (2010)

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Leptin Signaling Protects NK Cells from Apoptosis During Development in Mouse Bone Marrow

Cherry Kam Chun Lo et al.

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Induction of proinflammatory cytokines and caspase-1 by leptin in monocyte/macrophages from Holstein cows

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A key role of leptin in the control of regulatory T cell proliferation

Veronica De Rosa et al.

IMMUNITY (2007)

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Visceral fat adipokine secretion is associated with systemic inflammation in obese humans

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Development of leptin antagonists and their potential use in experimental biology and medicine

Arieh Gertler

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2006)

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Weight-dependent changes of immune system in adipose tissue:: Importance of leptin

S. Caspar-Bauguil et al.

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Intracellular signalling pathways activated by leptin

G Fruhbeck

BIOCHEMICAL JOURNAL (2006)

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Leptin is an eosinophil survival factor

S Conus et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2005)

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Adipose tissue, adipokines, and inflammation

G Fantuzzi

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Expression of leptin receptors and response to leptin stimulation of human natural killer cell lines

YR Zhao et al.

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Article Biochemistry & Molecular Biology

Impaired natural killer (NK) cell activity in leptin receptor deficient mice: leptin as a critical regulator in NK cell development and activation

ZG Tian et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)

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Serum leptin and CD4+ T lymphocytes in HIV+ children during highly active antiretroviral therapy

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CLINICAL ENDOCRINOLOGY (2002)

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Leptin-deficient mice exhibit impaired host defense in gram-negative pneumonia

P Mancuso et al.

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Leptin regulation of the immune response and the immunodeficiency of malnutrition

R Faggioni et al.

FASEB JOURNAL (2001)

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Elevated serum leptin concentrations induced by experimental acute inflammation

O Gualillo et al.

LIFE SCIENCES (2000)

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Leptin-deficient (ob/ob) mice are protected from T cell-mediated hepatotoxicity:: Role of tumor necrosis factor α and IL-18

R Faggioni et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

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Human leptin enhances activation and proliferation of human circulating T lymphocytes

C Martín-Romero et al.

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