期刊
EXPERT REVIEW OF CLINICAL IMMUNOLOGY
卷 9, 期 7, 页码 669-675出版社
TAYLOR & FRANCIS LTD
DOI: 10.1586/1744666X.2013.811187
关键词
alternatively activated macrophages; dendritic cells; immunomodulation; regulatory B cells; Treg; Trichinella spiralis
类别
Many epidemiological data support the postulate that infection with helminths might provide some protection against allergic and autoimmune diseases. Hence arises the concept that helminths strongly influence the immune system and enable protective pathways against these hyperimmune-associated disorders. This review discusses how Trichinella spiralis can make the immune system smarter in dealing with hyperimmune-associated disorders. T. spiralis possesses the capacity to direct the immune system towards a mixed Th1/Th2 phenotype with predominance of Th2 response, or it may interfere with dendritic cell maturation, induce the alternatively activated macrophages and elicit the regulatory arm of the immune response via Treg or regulatory B cells.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据