期刊
EXPERT REVIEW OF CLINICAL IMMUNOLOGY
卷 7, 期 5, 页码 593-602出版社
TAYLOR & FRANCIS LTD
DOI: 10.1586/ECI.11.52
关键词
angiogenesis; decidua; dendritic cells; fetomaternal tolerance; lymphatic vessel; myometrium; pregnancy
类别
资金
- NIH [RO1AI062980]
- American Cancer Society [RSG-10-158-01-LIB]
- Leona M and Harry B Helmsley Charitable Trust
Understanding the evolutionary adaptation of the immune system to the developing fetus and placenta represents one of the most fascinating problems in reproductive biology. Recent work has focused on how the behavior of dendritic cells (DCs) is altered at the maternal-fetal interface to suit the unique requirements of pregnancy. This work has provided a significant new perspective into the long-standing immunological paradox of fetomaternal tolerance, and has opened up a new and intriguing area of research into the potential trophic role of uterine DCs in the peri-implantation period. Further research on the biology of uterine DCs promises to give insight into the pathogenesis of many clinically important disorders of pregnancy.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据