期刊
EXPERT REVIEW OF CLINICAL IMMUNOLOGY
卷 6, 期 2, 页码 257-268出版社
TAYLOR & FRANCIS LTD
DOI: 10.1586/ECI.09.85
关键词
airway inflammation; asthma; combination therapy; corticosteroid; corticosteroid insensitivity; leukotriene-receptor antagonist; smoker; smoking cessation; theophylline
类别
Cigarette smoking is common in asthma and is associated with poor symptom control and a reduced therapeutic response to inhaled and oral corticosteroids as compared with nonsmokers with asthma. This review examines the range of adverse health effects of smoking in asthma, the inflammatory mechanisms that may influence the efficacy of current drugs and discusses potential future therapeutic directions.
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