期刊
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY
卷 12, 期 3, 页码 293-306出版社
TAYLOR & FRANCIS LTD
DOI: 10.1586/14787210.2014.885837
关键词
antiretroviral therapy; HIV-infection; lopinavir; preterm birth; prevention; protease inhibitors; risk factors; ritonavir; zidovudine
资金
- Abbvie
- British HIV Association
- PANNA network
- Wellcome Trust
- Leukaemia Lymphoma Research
- Medical Research Council
The use of combination antiretroviral therapy for the prevention of mother to child transmission of HIV infection has achieved vertical HIV transmission rates of <1%. The use of these drugs is not without risk to the mother and infant. Pregnant women with HIV-infection are at high risk of preterm birth (PTB <37 weeks), with 2-4-fold the risk of uninfected women. There is accumulating evidence that certain combinations are associated with higher rates of PTB that others or no antiretroviral treatment. Understanding the pathogenesis of PTB in this group of women will be essential to target preventative strategies in the face of increasing HIV prevalence and rapidly expanding mother-to-child-transmission prevention programmes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据