期刊
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY
卷 10, 期 11, 页码 1331-1342出版社
TAYLOR & FRANCIS LTD
DOI: 10.1586/ERI.12.123
关键词
biomarker; flow cytometry; histology; intermittent screening and treatment; light microscopy; mass spectrometry; PCR; placental malaria; rapid diagnostic test; submicroscopic
资金
- Canadian Institutes of Health Research [MOP-13721, MOP-115160]
- Global Alliance to Prevent Preterm Birth and Stillbirth
- Grand Challenges in Global Health: Preventing Preterm Birth Initiative [12003]
- Canada Research Chair in Molecular Parasitology
Despite increased malaria control efforts, recent reports indicate that over 1.2 million deaths due to malaria occurred in 2010. Pregnant women represent a particularly vulnerable risk group as malaria infection can lead to life-threatening disease for the mother and fetus. With 125 million women at risk of malaria in pregnancy every year, better diagnostic tools are needed for timely identification and treatment of malaria infection. Diagnostic surveillance tools are also needed to estimate disease burden and inform public health policies. In this review, the authors focus on malaria diagnostics in pregnancy and discuss considerations for different Plasmodium species and geographic regions. The authors also look at promising diagnostic modalities to monitor fetal and maternal health in pregnancy and discuss implementation barriers for low resource settings.
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