期刊
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY
卷 10, 期 11, 页码 1279-1282出版社
EXPERT REVIEWS
DOI: 10.1586/ERI.12.122
关键词
Chagas disease; parasite burden; quantitative PCR; Trypanosoma cruzi; vertical transmission
资金
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior, Programa Nacional de Pos Doutorado (CAPES/PND Grant) [02883/09-0]
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
The congenital transmission of Trypanosoma cruzi has gained epidemiological importance because it is partially responsible for the spread of Chagas disease worldwide. The feasibility of a cure when infected children are treated early makes the detection of congenital infection a valuable goal toward the control of the disease. Here, the authors review and discuss the findings of Bua et al., who quantified the parasitemia of infected women and their newborns by quantitative PCR. The authors demonstrate that the maternal parasite burden is directly related to the risk of neonatal infection. This study points out the importance of a quantitative screen for T. cruzi in pregnant women who live in, or have traveled to, endemic areas for improving the diagnosis of infected newborns and providing prompt treatment.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据