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Costimulation of Dendritic Epidermal γδ T Cells by a New NKG2D Ligand Expressed Specifically in the Skin
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NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy
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Two novel NKG2D ligands of the mouse H60 family with differential expression patterns and binding affinities to NKG2D
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Chimeric NKG2D-Modified T cells inhibit systemic T-cell lymphoma growth in a manner involving multiple cytokines and cytotoxic pathways
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IL-2 immunotoxin denileukin diftitox reduces regulatory T cells and enhances vaccine-mediated T-cell immunity
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Differentiation-promoting drugs up-regulate NKG2D ligand expression and enhance the susceptibility of acute myeloid leukemia cells to natural killer cell-mediated lysis
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Regulation of the expression of MHC class I-related chain A, B (MICA, MICB) via chromatin remodeling and its impact on the susceptibility of leukemic cells to the cytotoxicity of NKG2D-expressing cells
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Molecular analysis of T-cell receptor β genes in cutaneous T-cell lymphoma reveals Jβ1 bias
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IL-2/IL-18 prevent the down-modulation of NKG2D by TGF-β in NK cells via the c-Jun N-terminal kinase (JNK) pathway
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Expression of the stress-related MHC class I chain-related protein MICA is an indicator of good prognosis in colorectal cancer patients
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Proteolytic release of soluble UL16-binding protein 2 from tumor cells
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Soluble MICA in malignant diseases
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IL-21 down-regulates NKG2D/DAP10 express on human NK and CD8+ T cells
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CD4+-CD25+ T regulatory cells suppress NK cell-mediated immunotherapy of cancer
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IFN-Dependent down-regulation of the NKG2D ligand H60 on tumors
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CEACAM1: contact-dependent control of immunity
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Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B
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CD4+ CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-β-dependent manner
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JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Inhibition of NK cell activity through TGF-β1 by down-regulation of NKG2D in a murine model of head and neck cancer
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JOURNAL OF IMMUNOLOGY (2005)
Interleukin-15 activates human natural killer cells to clear the intestinal protozoan Cryptosporidium
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NKG2D function protects the host from tumor initiation
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JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance
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NATURE IMMUNOLOGY (2005)
The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor
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IL-21 enhances tumor rejection through a NKG2D-dependent mechanism
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A critical function for type I interferons in cancer immunoediting
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Altered NKG2D function in NK cells induced by chronic exposure to NKG2D ligand-expressing tumor cells
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Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor
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IL-21 induces the functional maturation of murine NK cells
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Prevalent expression of the immunostimulatory MHC class I chain-related molecule is counteracted by shedding in prostate cancer
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Vδ1 T lymphocytes from B-CLL patients recognize ULBP3 expressed on leukemic B cells and up-regulated by trans-retinoic acid
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NKG2D blockade prevents autoimmune diabetes in NOD mice
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ANNUAL REVIEW OF IMMUNOLOGY (2004)
RNA interference targeting transforming growth factor-β enhances NKG2D-mediated antiglioma immune response, inhibits glioma cell migration and invasiveness, and abrogates tumorigenicity in vivo
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ANNUAL REVIEW OF IMMUNOLOGY (2004)
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Functional expression and release of ligands for the activating immunoreceptor NKG2D in leukemia
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Effects of human cytomegalovirus infection on ligands for the activating NKG2D receptor of NK cells:: Up-regulation of UL16-binding protein (ULBP)1 and ULBP2 is counteracted by the viral UL16 protein
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JOURNAL OF IMMUNOLOGY (2003)
NKG2D triggers cytotoxicity in mouse NK cells lacking DAP12 or Syk family kinases
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ULBP4 is a novel ligand for human NKG2D
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Transforming growth factor β1 inhibits expression of NKp30 and NKG2D receptors:: Consequences for the NK-mediated killing of dendritic cells
R Castriconi et al.
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NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation
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Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D
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Cutting edge: Tumor rejection mediated by NKG2D receptor-ligand interaction is dependent upon perforin
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Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation
V Groh et al.
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Cutting edge: Murine UL16-binding protein-like transcript 1: A newly described transcript encoding a high-affinity ligand for marine NKG2D
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JOURNAL OF IMMUNOLOGY (2002)
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Expression of stress-induced MHC class I related chain molecules on human melanoma
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JOURNAL OF INVESTIGATIVE DERMATOLOGY (2002)
Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development
K Takeda et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
Cutting edge: NKG2D receptors induced by IL-15 costimulate CD28-negative effector CTL in the tissue microenvironment
AI Roberts et al.
JOURNAL OF IMMUNOLOGY (2001)
Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor in vivo
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity
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NATURE (2001)
IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity
V Shankaran et al.
NATURE (2001)
ULBPs, novel MHC class I-related molecules bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor
D Cosman et al.
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Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma
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JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages
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NATURE IMMUNOLOGY (2000)
Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice
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IMMUNITY (2000)
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