相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Increased expression of p27 is associated with the cisplatin resistance in gastric cancer cell line YCC-3
Tuong Vy Thi Le et al.
ARCHIVES OF PHARMACAL RESEARCH (2010)
CaMKII phosphorylates serine 10 of p27 and confers apoptosis resistance to HeLa cells
Ryutaro Kajihara et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
MicroRNA and proliferation control in chronic lymphocytic leukemia: functional relationship between miR-221/222 cluster and p27
Michela Frenquelli et al.
BLOOD (2010)
Tumor suppressor p27Kip1 undergoes endolysosomal degradation through its interaction with sorting nexin 6
Jose J. Fuster et al.
FASEB JOURNAL (2010)
p27(kip1) Controls Cell Morphology and Motility by Regulating Microtubule-Dependent Lipid Raft Recycling
Barbara Belletti et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors
Sara Molatore et al.
MOLECULAR CANCER (2010)
A Pumilio-induced RNA structure switch in p27-3′ UTR controls miR-221 and miR-222 accessibility
Martijn Kedde et al.
NATURE CELL BIOLOGY (2010)
SRC: A Century of Science Brought to the Clinic
Alexey Aleshin et al.
NEOPLASIA (2010)
Bortezomib arrests the proliferation of hepatocellular carcinoma cells HepG2 and JHH6 by differentially affecting E2F1, p21 and p27 levels
Daniele Baiz et al.
BIOCHIMIE (2009)
Discrimination of Multiple Primary Lung Cancers From Intrapulmonary Metastasis Based on the Expression of Four Cancer-related Proteins
Kenji Ono et al.
CANCER (2009)
p27Kip1 in Stage III Colon Cancer: Implications for Outcome following Adjuvant Chemotherapy in Cancer and Leukemia Group B Protocol 89803
Monica M. Bertagnolli et al.
CLINICAL CANCER RESEARCH (2009)
Cytoplasmic Sequestration of p27 via AKT Phosphorylation in Renal Cell Carcinoma
Jinhee Kim et al.
CLINICAL CANCER RESEARCH (2009)
Interaction of Molecular Markers and Physical Activity on Mortality in Patients with Colon Cancer
Jeffrey A. Meyerhardt et al.
CLINICAL CANCER RESEARCH (2009)
Combined Src and Aromatase Inhibition Impairs Human Breast Cancer Growth In vivo and Bypass Pathways Are Activated in AZD0530-Resistant Tumors
Yi Chen et al.
CLINICAL CANCER RESEARCH (2009)
Pin1 Catalyzes Conformational Changes of Thr-187 in p27Kip1 and Mediates Its Stability through a Polyubiquitination Process
Qiaoyun Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility
Michelle D. Larreaa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Oncogenic properties and prognostic implications of the ubiquitin ligase Skp2 in cancer
Dan D. Hershko
CANCER (2008)
Argyrin A reveals a critical role for the tumor suppressor protein p27kip1 in mediating antitumor activities in response to proteasome inhibition
Irina Nickeleit et al.
CANCER CELL (2008)
Imatinib Mesylate Induces Quiescence in Gastrointestinal Stromal Tumor Cells through the CDH1-SKP2-p27Kip1 Signaling Axis
Ying Liu et al.
CANCER RESEARCH (2008)
Proteasome inhibitors in cancer therapy: Lessons from the first decade
Robert Z. Orlowski et al.
CLINICAL CANCER RESEARCH (2008)
MicroRNA-221/222 Confers Tamoxifen Resistance in Breast Cancer by Targeting p27Kip1
Tyler E. Miller et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4
Michelle D. Larrea et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
p27Kip1 expression inhibits glioblastoma growth, invasion, and tumor-induced neoangiogenesis
Monica Schiappacassi et al.
MOLECULAR CANCER THERAPEUTICS (2008)
MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma
F. Fornari et al.
ONCOGENE (2008)
Expression of p21waf1/cip1, p27kip1, p63 and androgen receptor in low and high Gleason score prostate cancer
Imre Romics et al.
PATHOLOGY & ONCOLOGY RESEARCH (2008)
The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy
Isabel M. Chu et al.
NATURE REVIEWS CANCER (2008)
Relocalized p27KiP1 tumor suppressor functions as a cytoplasmic metastatic oncogene in melanoma
Catherine Denicourt et al.
CANCER RESEARCH (2007)
Regulation of p27Kip1 by miRNA 221/222 in Glioblastoma
Jana K. Gillies et al.
CELL CYCLE (2007)
miR-221 and miR-222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1*
Silvia Galardi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Regulation of the p27Kip1 tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation
Carlos le Sage et al.
EMBO JOURNAL (2007)
Cyclin D2 translocates p27 out of the nucleus and promotes its degradation at the G0-G1 transition
Etsuo Susaki et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
p27Kip1 metabolism - A fascinating labyrinth
Adriana Borriello et al.
CELL CYCLE (2007)
Expression profiling identifies microRNA signature in pancreatic cancer
Eun Jon Lee et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
The energy sensing LKB1-AMPK pathway regulates p27kip1 phosphorylation mediating the decision to enter autophagy or apoptosis
Jiyong Liang et al.
NATURE CELL BIOLOGY (2007)
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
Isabel Chu et al.
CELL (2007)
Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases
Matthias Grimmler et al.
CELL (2007)
MicroRNAs (miR)-221 and miR-222, both overexpressed in human thyroid papillary carcinomas, regulate p27(Kip1) protein levels and cell cycle
Rosa Visone et al.
ENDOCRINE-RELATED CANCER (2007)
p27Kip1 and cyclin E expression and breast cancer survival after treatment with adjuvant chemotherapy
Peggy L. Porter et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2006)
Calpain activation is required for glutamate-induced p27 down-regulation in cultured cortical neurons
Hiroki Akashiba et al.
JOURNAL OF NEUROCHEMISTRY (2006)
The COP9 signalosome regulates Skp2 levels and proliferation of human cells
Simona Denti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Cytoplasmic expression of p27kip1 is associated with a favourable prognosis in colorectal cancer patients
Nicholas F. S. Watson et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2006)
Coupling cell cycle exit, neuronal differentiation and migration in cortical neurogenesis
Laurent Nguyen et al.
CELL CYCLE (2006)
p27Kip1 and cyclin dependent kinase 2 regulate passage through the restriction point
Masahiro Hitomi et al.
CELL CYCLE (2006)
Testing the importance of p27 degradation by the SCFskp2 oathwav in murine models of lung and colon cancer
Inke Timmerbeul et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Cul4A targets p27 for degradation and regulates proliferation, cell cycle exit, and differentiation during erythropoiesis
Binghui Li et al.
BLOOD (2006)
p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex
Laurent Nguyen et al.
GENES & DEVELOPMENT (2006)
Retinoic acid induces P27Kip1 nuclear accumulation by modulating its phosphorylation
A Borriello et al.
CANCER RESEARCH (2006)
Reduction of cytosolic p27Kip1 inhibits cancer cell motility, survival, and tumorigenicity
FY Wu et al.
CANCER RESEARCH (2006)
Biological correlates of p27 compartmental expression in prostate cancer
R Li et al.
JOURNAL OF UROLOGY (2006)
Tyrosine phosphorylation modulates binding preference to cyclin-dependent kinases and subcellular localization of P27Kip1 in the acute promyelocytic leukemia cell line NB4
C Kardinal et al.
BLOOD (2006)
Cdk5 phosphorylates and stabilizes p27(kip1) contributing to actin organization and cortical neuronal migration
T Kawauchi et al.
NATURE CELL BIOLOGY (2006)
A pathway in quiescent cells that controls p27(Kip1) stability, subcellular localization, and tumor suppression
A Besson et al.
GENES & DEVELOPMENT (2006)
Disordered p27Kip1 exhibits intrinsic structure resembling the Cdk2/cyclin A-bound conformation
SG Sivakolundu et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Cdc2-cyclin E complexes regulate the G1/S phase transition
E Aleem et al.
NATURE CELL BIOLOGY (2005)
Molecular basis for the specificity of p27 toward cyclin-dependent kinases that regulate cell division
ER Lacy et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase
S Kotoshiba et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Using kinetic studies to uncover new Rb functions in inhibiting cell cycle progression
P Ji et al.
CELL CYCLE (2005)
Role of serine 10 phosphorylation in p27 stabilization revealed by analysis of p27 knock-in mice harboring a serine 10 mutation
Y Kotake et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion
G Baldassarre et al.
CANCER CELL (2005)
Histone deacetylase inhibition-mediated post-translational elevation of p27(kip1) protein levels is required for G(1) arrest in fibroblasts
JS Chen et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2005)
p27Kip1 modulates cell migration through the regulation of RhoA activation
A Besson et al.
GENES & DEVELOPMENT (2004)
p27 binds cyclin-CDK complexes through a sequential mechanism involving binding-induced protein folding
ER Lacy et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27Kip1 at G1 phase
T Kamura et al.
NATURE CELL BIOLOGY (2004)
The cyclin-dependent kinase inhibitor p27Kip1 is stabilized in G0 by Mirk/dyrk1B kinase
XB Deng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
TJ Lynch et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27Kip1
T Sekimoto et al.
EMBO JOURNAL (2004)
Phosphorylation of p27Kip1 at threonine 198 by p90 ribosomal protein S6 kinases promotes its binding to 14-3-3 and cytoplasmic localization
N Fujita et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Epidermal growth factor receptor in non-small-cell lung carcinomas:: Correlation between gene copy number and protein expression and impact on prognosis
FR Hirsch et al.
JOURNAL OF CLINICAL ONCOLOGY (2003)
Retinoic acid inhibits the growth of bone marrow mesenchymal stem cells and induces p27Kip1 and p16INK4A up-regulation
A Oliva et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2003)
MAP kinase-dependent degradation of p27Kip1 by calpains in choroidal melanoma cells -: Requirement of p27Kip1 nuclear export
C Delmas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Decreased immunoreactivity for p27 protein in patients with early-stage breast carcinoma is correlated with HER-2/neu overexpression and with benefit from one course of perioperative chemotherapy in patients with negative lymph node status -: Results from International Breast Cancer Study Group Trial V
VJ Spataro et al.
CANCER (2003)
Coordinate control of proliferation and migration by the p27Kip1/cyclin-dependent kinase/retinoblastoma pathway in vascular smooth muscle cells and fibroblasts
A Díez-Juan et al.
CIRCULATION RESEARCH (2003)
CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis
MK Connor et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
Multiple Roles of the PI3K/PKB (Akt) Pathway in Cell Cycle Progression
Jiyong Liang et al.
CELL CYCLE (2003)
Keeping p27Kip1 in the Cytoplasm A Second Front in Cancer's War on p27
Steven I. Reed
CELL CYCLE (2002)
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27Kip1 by PKB/Akt-mediated phosphorylation in breast cancer
G Viglietto et al.
NATURE MEDICINE (2002)
PKB/Akt mediates cell-cycle progression by phosphorylation of p27Kip1 at threonine 157 and modulation of its cellular localization
I Shin et al.
NATURE MEDICINE (2002)
PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest
J Liang et al.
NATURE MEDICINE (2002)
Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization
N Fujita et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
A growth factor-dependent nuclear kinase phosphorylates p27Kip1 and regulates cell cycle progression
M Boehm et al.
EMBO JOURNAL (2002)
Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export
N Ishida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Low expression of p27Kip1 is associated with tumor size and poor prognosis in patients with renal cell carcinoma
T Migita et al.
CANCER (2002)
p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis
G Rodier et al.
EMBO JOURNAL (2001)
Histone deacetylases and cancer: Causes and therapies
PA Marks et al.
NATURE REVIEWS CANCER (2001)
Overexpression of p27Kip1 by doxycycline-regulated adenoviral vectors inhibits endothelial cell proliferation and migration and impairs angiogenesis
D Goukassian et al.
FASEB JOURNAL (2001)
Role for p27Kip1, vascular smooth muscle cell migration
J Sun et al.
CIRCULATION (2001)
Effects of macromolecular crowding on the intrinsically disordered proteins c-Fos and p27Kip1
SL Flaugh et al.
BIOMACROMOLECULES (2001)
Direct binding of the signal-transducing adaptor Grb2 facilitates down-regulation of the cyclin-dependent kinase inhibitor p27Kip1
Y Sugiyama et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The cell-cycle regulatory protein Cks1 is required for SCFSkp2-mediated ubiquitinylation of p27
D Ganoth et al.
NATURE CELL BIOLOGY (2001)
Phosphorylation at serine 10, a major phosphorylation site of p27Kip1, increases its protein stability
N Ishida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
p27Kip1 accumulation is associated with retinoic-induced neuroblastoma differentiation:: evidence of a decreased proteasome-dependent degradation
A Borriello et al.
ONCOGENE (2000)
分享论文
