4.5 Review

TRPM2 channel properties, functions and therapeutic potentials

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Regulation of TRP channel TRPM2 by the tyrosine phosphatase PTPL1

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Inhibition of TRPM2 cation channels by N-(p-amylcinnamoyl)anthranilic acid

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Trafficking and assembly of the cold-sensitive TRPM8 channel

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A polyclonal antibody to the prepore loop of transient receptor potential vanilloid type 1 blocks channel activation

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Coiled coils direct assembly of a cold-activated TRP channel

Pamela R. Tsuruda et al.

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Tamara M. Paravicini et al.

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Metabolite of SIR2 reaction modulates TRPM2 ion channel

Olivera Grubisha et al.

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TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion

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A critical role of TRPM2 in neuronal cell death hy hydrogen peroxide

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Tissue distribution profiles of the human TRPM cation channel family

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TRPM2 is elevated in the tMCAO stroke model, transcriptionally regulated, and functionally expressed in C13 microglia

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Regulation of the transient receptor potential channel TRPM2 by the Ca2+ sensor calmodulin

Q Tong et al.

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TRPM2 is an ion channel that modulates hematopoietic cell death through activation of caspases and PARP cleavage

WY Zhang et al.

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Activation of T cell calcium influx by the second messenger ADP-ribose

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Association of the putative susceptibility gene, transient receptor potential protein melastatin type 2, with bipolar disorder

C Xu et al.

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Amyloid β-peptide(1-42) and hydrogen peroxide-induced toxicity are mediated by TRPM2 in rat primary striatal cultures

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SZ Xu et al.

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T Voets et al.

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Reactive oxygen species and the modulation of stroke

PJ Crack et al.

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Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels

M Kolisek et al.

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Characterization of human and mouse TRPM2 genes:: Identification of a novel N-terminal truncated protein specifically expressed in human striatum

T Uemura et al.

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Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels

AL Perraud et al.

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Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole

K Hill et al.

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Flufenamic acid is a pH-dependent antagonist of TRPM2 channels

K Hill et al.

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TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase

E Fonfria et al.

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2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3

HZ Hu et al.

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The TRPM ion channel subfamily: molecular, biophysical and functional features

A Fleig et al.

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Hydrogen peroxide and ADP-ribose induce TRPM2-mediated calcium influx and cation currents in microglia

R Kraft et al.

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Sites of the NUDT9-H domain critical for ADP-ribose activation of the cation channel TRPM2

FJP Kühn et al.

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TRP channels as cellular sensors

DE Clapham

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A novel TRPM2 isoform inhibits calcium influx and susceptibility to cell death

W Zhang et al.

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Critical intracellular Ca2+ dependence of transient receptor potential melastatin 2 (TRPM2) cation channel activation

D McHugh et al.

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Response to ADP-ribose by activation of TRPM2 in the CRI-G1 insulinoma cell line

K Inamura et al.

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Y Taniyama et al.

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Role of Ca2+ signaling in the regulation of endothelial permeability

C Tiruppathi et al.

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The TRP channels, a remarkably functional family

C Montell et al.

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Immunocyte Ca2+ influx system mediated by LTRPC2

Y Sano et al.

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The versatility and universality of calcium signalling

MJ Berridge et al.

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Oxidative stress in Alzheimer's disease

MA Smith et al.

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Calcium signaling and oxidant stress in the vasculature

KM Lounsbury et al.

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From worm to man: three subfamilies of TRP channels

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