4.5 Review

Direct AMP-activated protein kinase activators: a review of evidence from the patent literature

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Cell Biology

AMPK: a nutrient and energy sensor that maintains energy homeostasis

D. Grahame Hardie et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)

Article Biochemistry & Molecular Biology

AMP-activated protein kinase undergoes nucleotide-dependent conformational changes

Lei Chen et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)

Review Chemistry, Medicinal

AMP-activated protein kinase modulators: a patent review (2006-2010)

Hee Yun et al.

EXPERT OPINION ON THERAPEUTIC PATENTS (2011)

Article Cardiac & Cardiovascular Systems

A small molecule AMPK activator protects the heart against ischemia-reperfusion injury

Agnes S. Kim et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2011)

Article Multidisciplinary Sciences

Structure of mammalian AMPK and its regulation by ADP

Bing Xiao et al.

NATURE (2011)

Article Multidisciplinary Sciences

AMPK Is a Direct Adenylate Charge-Regulated Protein Kinase

Jonathan S. Oakhill et al.

SCIENCE (2011)

Review Biochemistry & Molecular Biology

AMP-activated protein kinase: also regulated by ADP?

D. Grahame Hardie et al.

TRENDS IN BIOCHEMICAL SCIENCES (2011)

Article Biochemistry & Molecular Biology

Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer

S. Fogarty et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2010)

Article Multidisciplinary Sciences

β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK)

Jonathan S. Oakhill et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Cell Biology

AMP-activated protein kinase activator A-769662 is an inhibitor of the Na+-K+-ATPase

Boubacar Benziane et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2009)

Article Cell Biology

Inhibition of the KCa3.1 channels by AMP-activated protein kinase in human airway epithelial cells

Helene Klein et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2009)

Article Pharmacology & Pharmacy

Inhibitory Effects of A-769662, a Novel Activator of AMP-Activated Protein Kinase, on 3T3-L1 Adipogenesis

Yi Zhou et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2009)

Article Biochemistry & Molecular Biology

Mechanistic Insight into Control of CFTR by AMPK

Patthara Kongsuphol et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Neurosciences

AMP-activated protein kinase inhibits TREK channels

Orsolya Kreneisz et al.

JOURNAL OF PHYSIOLOGY-LONDON (2009)

Review Physiology

AMPK in Health and Disease

Gregory R. Steinberg et al.

PHYSIOLOGICAL REVIEWS (2009)

Article Biochemistry & Molecular Biology

Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice

Xu Huang et al.

BIOCHEMICAL JOURNAL (2008)

Article Biochemistry & Molecular Biology

Thienopyridone Drugs Are Selective Activators of AMP-Activated Protein Kinase β1-Containing Complexes

John W. Scott et al.

CHEMISTRY & BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Small molecule antagonizes autoinhibition and activates AMP-activated protein kinase in cells

Tao Pang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase

Olga Goeransson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family

Matthew J. Sanders et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Chemistry, Medicinal

Discovery and SAR development of thienopyridones: A class of small molecule AMPK activators

Gang Zhao et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)

Review Endocrinology & Metabolism

AMP-activated protein kinase and the regulation of glucose transport

Nobuharu Fujii et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)

Article Biochemistry & Molecular Biology

Dissecting the role of 5′-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase

Marianne Suter et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Review Cell Biology

CBS domains: structure, function, and pathology in human proteins

S Ignoul et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2005)

Article Biochemistry & Molecular Biology

Epithelial sodium channel inhibition by AMP-activated protein kinase in oocytes and polarized renal epithelial cells

MD Carattino et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Multidisciplinary Sciences

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

RJ Shaw et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

Intrasteric control of AMPK via the gamma(1) subunit AMP allosteric regulatory site

J Adams et al.

PROTEIN SCIENCE (2004)

Article Multidisciplinary Sciences

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Y Minokoshi et al.

NATURE (2002)

Article Medicine, Research & Experimental

Role of AMP-activated protein kinase in mechanism of metformin action

GC Zhou et al.

JOURNAL OF CLINICAL INVESTIGATION (2001)