相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。CDC25A and B Dual-Specificity Phosphatase Inhibitors: Potential Agents for Cancer Therapy
Antonio Lavecchia et al.
CURRENT MEDICINAL CHEMISTRY (2009)
IRC-083864, a novel his quinone inhibitor of CDC25 phosphatases active against human cancer cells
Marie-Christine Brezak et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Rapid Discovery of Triazolobenzylidene-Thiazolopyrimidines (TBTP) as CDC25 Phosphatase Inhibitors by Parallel Click Chemistry and in Situ Screening
Romain Duval et al.
JOURNAL OF COMBINATORIAL CHEMISTRY (2009)
Mechanism of Cdc25B Phosphatase with the Small Molecule Substrate p-Nitrophenyl Phosphate from QM/MM-MFEP Calculations
Jerry M. Parks et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2009)
Exploring structural variability in X-ray crystallographic models using protein local optimization by torsion-angle sampling
Jennifer L. Knight et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2008)
Cdc25B Phosphatase Inhibitors in Cancer Therapy: Latest Developments, Trends and Medicinal Chemistry Perspective
Antonio Lavecchia et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2008)
Synthetic small molecule Cdc25 phosphatases inhibitors
Laura Garuti et al.
CURRENT MEDICINAL CHEMISTRY (2008)
Receptor-based virtual ligand screening for the identification of novel CDC25 phosphatase inhibitors
Matthieu Montes et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2008)
The Catalytic Acid in the Dephosphorylation of the Cdk2-pTpY/CycA Protein Complex by Cdc25B Phosphatase
Guilherme Menegon Arantes
JOURNAL OF PHYSICAL CHEMISTRY B (2008)
Reaching for high-hanging fruit in drug discovery at protein-protein interfaces
James A. Wells et al.
NATURE (2007)
What's new on CDC25 phosphatase inhibitors
Marie-Odile Contour-Galcera et al.
PHARMACOLOGY & THERAPEUTICS (2007)
Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability
Dipankar Ray et al.
CANCER RESEARCH (2007)
Pharmacologic inhibition of CDC25 phosphatases impairs interphase microtubule dynamics and mitotic spindle assembly
Martine Cazales et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Free-energy profiles for catalysis by dual-specificity phosphatases
Guilherme M. Arantes
BIOCHEMICAL JOURNAL (2006)
PM-20, a novel inhibitor of Cdc25A, induces extracellular signal-regulated kinase 1/2 phosphorylation and inhibits hepatocellular carcinoma growth in vitro and in vivo
Siddhartha Kar et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Modeling of Cdc25B dual specifity protein phosphatase inhibitors: Docking of ligands and enzymatic inhibition mechanism
Antonio Lavecchia et al.
CHEMMEDCHEM (2006)
Synthesis and biological evaluation of dimeric cinnamaldehydes as potent antitumor agents
DS Shin et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2006)
Novel procedure for modeling ligand/receptor induced fit effects
W Sherman et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
Cdc25: mechanisms of checkpoint inhibition and recovery
Christina Karisson-Rosenthal et al.
TRENDS IN CELL BIOLOGY (2006)
Targeting protein-protein interactions with small molecules: Challenges and perspectives for computational binding epitope detection and ligand finding
Domingo Gonzalez-Ruiz et al.
CURRENT MEDICINAL CHEMISTRY (2006)
Experimental validation of the docking orientation of Cdc25 with its Cdk2-CycA protein substrate
R Sohn et al.
BIOCHEMISTRY (2005)
A novel cinnamic acid derivative that inhibits Cdc25 dual-specificity phosphatase activity
Y Aoyagi et al.
CANCER SCIENCE (2005)
Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of CDC25 phosphatases
MC Brezak et al.
MOLECULAR CANCER THERAPEUTICS (2005)
Increased expression and activity of CDC25C phosphatase and an alternatively spliced variant in prostate cancer
M Ozen et al.
CLINICAL CANCER RESEARCH (2005)
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
LT Vassilev et al.
SCIENCE (2004)
Cdc25 phosphatases and cancer
K Kristjánsdóttir et al.
CHEMISTRY & BIOLOGY (2004)
Remote hot spots mediate protein substrate recognition for the Cdc25 phosphatase
J Sohn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Protein tyrosine phosphatases in the human genome
A Alonso et al.
CELL (2004)
DNA damage checkpoint control in cells exposed to ionizing radiation
G Iliakis et al.
ONCOGENE (2003)
Molecular design and biological activities of protein-tyrosine phosphatase inhibitors
K Umezawa et al.
PHARMACOLOGY & THERAPEUTICS (2003)
Dual-specificity phosphatases as targets for antineoplastic agents
MA Lyon et al.
NATURE REVIEWS DRUG DISCOVERY (2002)
Solid-phase synthesis of dysidiolide-derived protein phosphatase inhibitors
D Brohm et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
The catalytic mechanism of Cdc25A phosphatase
DF McCain et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Total Synthesis and Determination of the Absolute Configuration of Coscinosulfate. A New Selective Inhibitor of Cdc25 Protein Phosphatase
S Poigny et al.
JOURNAL OF ORGANIC CHEMISTRY (2001)
Expression of the cdc25B mRNA correlated with that of N-myc in neuroblastoma
Y Sato et al.
JAPANESE JOURNAL OF CLINICAL ONCOLOGY (2001)
Molecular reactions of protein phosphatases - Insights from structure and chemistry
MD Jackson et al.
CHEMICAL REVIEWS (2001)
Syntheses and biological activities of a novel group of steroidal derived inhibitors for human CDC25A protein phosphatase
HR Peng et al.
JOURNAL OF MEDICINAL CHEMISTRY (2001)
Total synthesis of natural dysidiolide
H Miyaoka et al.
JOURNAL OF ORGANIC CHEMISTRY (2001)
Synthesis of the novel analogues of dysidiolide and their structure-activity relationship
M Takahashi et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2000)
Dual-specific Cdc25B phosphatase: In search of the catalytic acid
W Chen et al.
BIOCHEMISTRY (2000)
Role of the Cdc25A phosphatase in human breast cancer
MG Cangi et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis
M Molinari et al.
EMBO REPORTS (2000)
Identification of new Cdc25 dual specificity phosphatase inhibitors in a targeted small molecule array
AP Ducruet et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2000)
Centrosomal and cytoplasmic cdc2/cyclin B1 activation precedes nuclear mitotic events
CPC De Souza et al.
EXPERIMENTAL CELL RESEARCH (2000)
Synthesis of a novel class of cdc25A inhibitors from vitamin D3
K Dodo et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2000)
A long twentieth century of the cell cycle and beyond
P Nurse
CELL (2000)