4.5 Review

TRPA1 modulators in preclinical development

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Gastroenterology & Hepatology

TRPA1 in bradykinin-induced mechanical hypersensitivity of vagal C fibers in guinea pig esophagus

Shaoyong Yu et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2009)

Article Cardiac & Cardiovascular Systems

Transient receptor potential melastatin 8 channel involvement in the regulation of vascular tone

Christopher D. Johnson et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)

Article Biochemistry & Molecular Biology

Essential role for the putative S6 inner pore region in the activation gating of the human TRPA1 channel

Jan Benedikt et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)

Review Neurosciences

Roles of transient receptor potential channels in pain

Cheryl L. Stucky et al.

BRAIN RESEARCH REVIEWS (2009)

Letter Physiology

TRPA1: the species difference

Jun Chen et al.

JOURNAL OF GENERAL PHYSIOLOGY (2009)

Editorial Material Physiology

Burning Cold: Involvement of TRPA1 in Noxious Cold Sensation

Kelvin Y. Kwan et al.

JOURNAL OF GENERAL PHYSIOLOGY (2009)

Article Neurosciences

TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons

Kelvin Y. Kwan et al.

JOURNAL OF NEUROSCIENCE (2009)

Article Neurosciences

Pharmacological blockade of TRPA1 inhibits mechanical firing in nociceptors

Patrick C. Kerstein et al.

MOLECULAR PAIN (2009)

Article Neurosciences

Pore dilation occurs in TRPA1 but not in TRPM8 channels

Jun Chen et al.

MOLECULAR PAIN (2009)

Article Biochemistry & Molecular Biology

Zinc activates damage-sensing TRPA1 ion channels

Hongzhen Hu et al.

NATURE CHEMICAL BIOLOGY (2009)

Review Biotechnology & Applied Microbiology

Transient receptor potential channels: targeting pain at the source

Ardem Patapoutian et al.

NATURE REVIEWS DRUG DISCOVERY (2009)

Article Multidisciplinary Sciences

TRPA1 acts as a cold sensor in vitro and in vivo

Yuji Karashima et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma

Ana I. Caceres et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

Clioquinol and pyrithione activate TRPA1 by increasing intracellular Zn2+

David A. Andersson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Pharmacology & Pharmacy

TRPA1: A potential target for anti-tussive therapy

Thomas E. Taylor-Clark et al.

PULMONARY PHARMACOLOGY & THERAPEUTICS (2009)

Article Physiology

Functional TRP and ASIC-like channels in cultured urothelial cells from the rat

F. Aura Kullmann et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2009)

Article Cell Biology

Inhibition of transient receptor potential A1 channel by phosphatidylinositol-4,5-bisphosphate

Donghee Kim et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2008)

Article Biochemistry & Molecular Biology

TRPA1 channels Novel targets of 1,4-dihydropyridines

Otto Fajardo et al.

CHANNELS (2008)

Article Biochemistry & Molecular Biology

TRPA1 mediates the noxious effects of natural sesquiterpene deterrents

Jasmine Escalera et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

The Nociceptor Ion Channel TRPA1 Is Potentiated and Inactivated by Permeating Calcium Ions

Yuanyuan Y. Wang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Medicine, Research & Experimental

TRPA1 is a major oxidant sensor in murine airway sensory neurons

Bret F. Bessac et al.

JOURNAL OF CLINICAL INVESTIGATION (2008)

Article Neurosciences

Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress

David A. Andersson et al.

JOURNAL OF NEUROSCIENCE (2008)

Article Neurosciences

Molecular determinants of species-specific activation or blockade of TRPA1 channels

Jun Chen et al.

JOURNAL OF NEUROSCIENCE (2008)

Article Neurosciences

Expression and function of the ion channel TRPA1 in vagal afferent nerves innervating mouse lungs

Christina Nassenstein et al.

JOURNAL OF PHYSIOLOGY-LONDON (2008)

Article Neurosciences

Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPAI

Lillian Cruz-Orengo et al.

MOLECULAR PAIN (2008)

Review Neurosciences

Molecular and cellular limits to somatosensory specificity

Carlos Belmonte et al.

MOLECULAR PAIN (2008)

Review Urology & Nephrology

On the origin of bladder sensing: Tr(i)ps in urology

Wouter Everaerts et al.

NEUROUROLOGY AND URODYNAMICS (2008)

Article Physiology

Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4,5-biphosphate manipulators

Yuji Karashima et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2008)

Article Multidisciplinary Sciences

Caffeine activates mouse TRPA1 channels but suppresses human TRPA1 channels

Katsuhiro Nagatomo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Review Pharmacology & Pharmacy

Body-temperature maintenance as the predominant function of the vanilloid receptor TRPV1

Narender R. Gavva

TRENDS IN PHARMACOLOGICAL SCIENCES (2008)

Article Behavioral Sciences

Time course of self-desensitization of oral irritation by nicotine and capsaicin

Earl Carstens et al.

CHEMICAL SENSES (2007)

Article Neurosciences

Bimodal action of menthol on the transient receptor potential channel TRPA1

Yuji Karashima et al.

JOURNAL OF NEUROSCIENCE (2007)

Article Multidisciplinary Sciences

TRPA1 mediates formalin-induced pain

Colleen R. McNamara et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1

Marcello Trevisani et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Neurosciences

Cold sensitivity of recombinant TRPA1 channels

Yosuke Sawada et al.

BRAIN RESEARCH (2007)

Article Medicine, Research & Experimental

Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain

Yi Dai et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

Article Biochemistry & Molecular Biology

Transient receptor potential channel a1 is directly gated by calcium ions

Julia F. Doerner et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Neurosciences

Attenuated cold sensitivity in TRPM8 null mice

Raymond W. Colburn et al.

NEURON (2007)

Article Neurosciences

Caenorhabditis elegans TRPA-1 functions in mechanosensation

Katie S. Kindt et al.

NATURE NEUROSCIENCE (2007)

Article Biochemistry & Molecular Biology

TRPA1 is differentially modulated by the amphipathic molecules trinitrophenol and chlorpromazine

Kerstin Hill et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Neurosciences

Direct activation of the ion channel TRPA1 by Ca2+

Sandra Zurborg et al.

NATURE NEUROSCIENCE (2007)

Article Multidisciplinary Sciences

Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines

Lindsey J. Macpherson et al.

NATURE (2007)

Article Multidisciplinary Sciences

TRP channel activation by reversible covalent modification

Andrew Hinman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Neurosciences

Mechanisms of neuropathic pain

James N. Campbell et al.

NEURON (2006)

Article Neurosciences

More than cool: Promiscuous relationships of menthol and other sensory compounds

Lindsey J. Macpherson et al.

MOLECULAR AND CELLULAR NEUROSCIENCE (2006)

Article Biochemistry & Molecular Biology

TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents

DM Bautista et al.

Article Multidisciplinary Sciences

Pungent products from garlic activate the sensory ion channel TRPA1

DM Bautista et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

The pungency of garlic: Activation of TRPA1 and TRPV1 in response to allicin

LJ Macpherson et al.

CURRENT BIOLOGY (2005)

Review Cell Biology

TRP channels: An overview

SF Pedersen et al.

CELL CALCIUM (2005)

Review Multidisciplinary Sciences

TRP channels as cellular sensors

DE Clapham

NATURE (2003)

Review Cell Biology

1,4-dihydropyridines as calcium channel ligands and privileged structures

DJ Triggle

CELLULAR AND MOLECULAR NEUROBIOLOGY (2003)

Article Biochemistry & Molecular Biology

painless, a Drosophila gene essential for nociception

WD Tracey et al.

Article Biochemistry & Molecular Biology

A TRP channel that senses cold stimuli and menthol

AM Peier et al.

Article Pharmacology & Pharmacy

Pathobiology of neuropathic pain

M Zimmermann

EUROPEAN JOURNAL OF PHARMACOLOGY (2001)