相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The Origins and Drivers of Insulin Resistance
Andrew M. F. Johnson et al.
CELL (2013)
被撤回的出版物: Tub Has a Key Role in Insulin and Leptin Signaling and Action In Vivo in Hypothalamic Nuclei(Retracted article. See vol. 66, pg. 785, 2017) (Publication with Expression of Concern. See vol. 65, pg. 1121, 2016) (Retracted article. See vol. 66, pg. 785, 2017)
Patricia O. Prada et al.
DIABETES (2013)
Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains
Romain Volmer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Role of Endoplasmic Reticulum Stress in Metabolic Disease and Other Disorders
Lale Ozcan et al.
ANNUAL REVIEW OF MEDICINE, VOL 63 (2012)
Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure
Chutima Talchai et al.
CELL (2012)
Hepatocyte Growth Factor Plays a Key Role in Insulin Resistance-Associated Compensatory Mechanisms
Tiago G. Araujo et al.
ENDOCRINOLOGY (2012)
Topiramate Treatment Improves Hypothalamic Insulin and Leptin Signaling and Action and Reduces Obesity in Mice
Andrea M. Caricilli et al.
ENDOCRINOLOGY (2012)
Double-Stranded RNA-Activated Protein Kinase Is a Key Modulator of Insulin Sensitivity in Physiological Conditions and in Obesity in Mice
M. A. Carvalho-Filho et al.
ENDOCRINOLOGY (2012)
Does the small tyrosine kinase inhibitor imatinib mesylate counteract diabetes by affecting pancreatic islet amyloidosis and fibrosis?
Nils Welsh
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2012)
Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome
Anne Vrieze et al.
GASTROENTEROLOGY (2012)
Enterococcus faecalis Enhances Cell Proliferation through Hydrogen Peroxide-Mediated Epidermal Growth Factor Receptor Activation
Kanitsak Boonanantanasarn et al.
INFECTION AND IMMUNITY (2012)
Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase
Saswata Talukdar et al.
NATURE MEDICINE (2012)
The cellular and signaling networks linking the immune system and metabolism in disease
Olivia Osborn et al.
NATURE MEDICINE (2012)
Protein-Folding Homeostasis in the Endoplasmic Reticulum and Nutritional Regulation
David Ron et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
Inflammatory Mechanisms in Obesity
Margaret F. Gregor et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 29 (2011)
Caloric restriction decreases ER stress in liver and adipose tissue in ob/ob mice
Atsuyuki Tsutsumi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Inflammation Is Necessary for Long-Term but Not Short-Term High-Fat Diet Induced Insulin Resistance
Yun Sok Lee et al.
DIABETES (2011)
被撤回的出版物: Physical Exercise Reduces Circulating Lipopolysaccharide and TLR4 Activation and Improves Insulin Signaling in Tissues of DIO Rats (Retracted article. See vol. 65, pg. 1124, 2016)
Alexandre G. Oliveira et al.
DIABETES (2011)
Inflammatory links between obesity and metabolic disease
Carey N. Lumeng et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
Daniel A. Winer et al.
NATURE MEDICINE (2011)
Effects of Imatinib Mesylate (Gleevec) on Human Islet NF-kappaB Activation and Chemokine Production In Vitro
Dariush Mokhtari et al.
PLOS ONE (2011)
Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis
Davina Wu et al.
SCIENCE (2011)
Gut Microbiota Is a Key Modulator of Insulin Resistance in TLR 2 Knockout Mice
Andrea M. Caricilli et al.
PLOS BIOLOGY (2011)
Propensity to high-fat diet-induced obesity in rats is associated with changes in the gut microbiota and gut inflammation
Claire Barbier de La Serre et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)
Double-Stranded RNA-Dependent Protein Kinase Links Pathogen Sensing with Stress and Metabolic Homeostasis
Takahisa Nakamura et al.
CELL (2010)
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
Goekhan S. Hotamisligil
CELL (2010)
Endoplasmic Reticulum Stress and Inflammation in Obesity and Diabetes
Sarah Hummasti et al.
CIRCULATION RESEARCH (2010)
Improved Glycemic Control With the Multi-Receptor Tyrosine Kinase Inhibitor Pazopanib
S. Bohm et al.
DIABETES CARE (2010)
Alternative Activation of Macrophages: Mechanism and Functions
Siamon Gordon et al.
IMMUNITY (2010)
T-Cell Recruitment and Th1 Polarization in Adipose Tissue During Diet-Induced Obesity in C57BL/6 Mice
Katherine J. Strissel et al.
OBESITY (2010)
High-Fat Diet: Bacteria Interactions Promote Intestinal Inflammation Which Precedes and Correlates with Obesity and Insulin Resistance in Mouse
Shengli Ding et al.
PLOS ONE (2010)
IL-6 and IL-10 Anti-Inflammatory Activity Links Exercise to Hypothalamic Insulin and Leptin Sensitivity through IKKβ and ER Stress Inhibition
Eduardo R. Ropelle et al.
PLOS BIOLOGY (2010)
Effect of the tyrosine kinase inhibitors (sunitinib, sorafenib, dasatinib, and imatinib) on blood glucose levels in diabetic and nondiabetic patients in general clinical practice
Nicole M Agostino et al.
JOURNAL OF ONCOLOGY PHARMACY PRACTICE (2010)
The Protein Kinase IKKε Regulates Energy Balance in Obese Mice
Shian-Huey Chiang et al.
CELL (2009)
EGFR Tyrosine Kinase Inhibitor (PD153035) Improves Glucose Tolerance and Insulin Action in High-Fat Diet-Fed Mice
Patricia O. Prada et al.
DIABETES (2009)
Imatinib Mesylate Reduces Endoplasmic Reticulum Stress and Induces Remission of Diabetes in db/db Mice
Myoung Sook Han et al.
DIABETES (2009)
Human Adipose Tissue Macrophages: M1 and M2 Cell Surface Markers in Subcutaneous and Omental Depots and after Weight Loss
Judith Aron-Wisnewsky et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
Chylomicrons promote intestinal absorption of lipopolysaccharides
Sarbani Ghoshal et al.
JOURNAL OF LIPID RESEARCH (2009)
A core gut microbiome in obese and lean twins
Peter J. Turnbaugh et al.
NATURE (2009)
Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice
Jian Liu et al.
NATURE MEDICINE (2009)
CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
Satoshi Nishimura et al.
NATURE MEDICINE (2009)
Normalization of obesity-associated insulin resistance through immunotherapy
Shawn Winer et al.
NATURE MEDICINE (2009)
Potential of Small Molecule Protein Tyrosine Kinase Inhibitors as Immunomodulators and Inhibitors of the Development of Diabetes
Peter J. Little et al.
THESCIENTIFICWORLDJOURNAL (2009)
Blood glucose levels in patients with metastatic renal cell carcinoma treated with sunitinib
B. Billemont et al.
BRITISH JOURNAL OF CANCER (2008)
Imatinib mesylate improves insulin sensitivity and glucose disposal rates in rats fed a high-fat diet
Robert Hagerkvist et al.
CLINICAL SCIENCE (2008)
Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals
Guenther Boden et al.
DIABETES (2008)
Reduction of hypothalamic protein tyrosine phosphatase improves insulin and leptin resistance in diet-induced obese rats
Paty Karoll Picardi et al.
ENDOCRINOLOGY (2008)
Fasting glucose improvement under dasatinib treatment in an accelerated phase chronic myeloid leukemia patient unresponsive to imatinib and nilotinib
M. Breccia et al.
LEUKEMIA RESEARCH (2008)
Intestinal, adipose, and liver inflammation in diet-induced obese mice
Hong Li et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2008)
Obesity and inflammation: the effects of weight loss
L. Kirsty Forsythe et al.
NUTRITION RESEARCH REVIEWS (2008)
β-cell failure as a complication of diabetes
K. J. Chang-Chen et al.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2008)
Remission of diabetes while on sunitinib treatment for renal cell carcinoma
A. Templeton et al.
ANNALS OF ONCOLOGY (2008)
A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via toll-like receptors 2 and 4 and JNK-dependent pathways
M. T. Audrey Nguyen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
被撤回的出版物: Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance (Retracted article. See vol. 65, pg. 1126, 2016)
Daniela M. L. Tsukumo et al.
DIABETES (2007)
Metabolic endotoxemia initiates obesity and insulin resistance
Patrice D. Cani et al.
DIABETES (2007)
Macrophage infiltration into omental versus subcutaneous fat across different populations:: Effect of regional adiposity and the comorbidities of obesity
Ilana Harman-Boehm et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)
Amelioration of diabetes by imatinib mesylate (Gleevec®):: role of β-cell NF-κB activation and anti-apoptotic preconditioning
Robert Hagerkvist et al.
FASEB JOURNAL (2007)
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
Carey N. Lumeng et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Lipopolysaccharide activates an innate immune system response in human adipose tissue in obesity and type 2 diabetes
S. J. Creely et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
Microbial ecology - Human gut microbes associated with obesity
Ruth E. Ley et al.
NATURE (2006)
TLR4 links innate immunity and fatty acid-induced insulin resistance
Hang Shi et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Improvement of type 2 diabetes in a lung cancer patient treated with erlotinib
Daniel B. Costa et al.
DIABETES CARE (2006)
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1α-mediated NF-κB activation and down-regulation of TRAF2 expression
P Hu et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Critical nodes in signalling pathways: insights into insulin action
CM Taniguchi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Obesity alters gut microbial ecology
RE Ley et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery induced weight loss
R Cancello et al.
DIABETES (2005)
Imatinib and regression of type 2 diabetes
D Veneri et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2
J Deng et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Imatinib mesylate may improve fasting blood glucose in diabetic Ph plus chronic myelogenous leukemia patients responsive to treatment
M Breccia et al.
JOURNAL OF CLINICAL ONCOLOGY (2004)
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
U Özcan et al.
SCIENCE (2004)
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1α interaction
P Puigserver et al.
NATURE (2003)
Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation
H Sano et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Obesity is associated with macrophage accumulation in adipose tissue
SP Weisberg et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
HY Xu et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
A central role for JNK in obesity and insulin resistance
J Hirosumi et al.
NATURE (2002)
Aph2, a protein with a zf-DHHC motif, interacts with c-Abl and has pro-apoptotic activity
BJ Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Nitric oxide-induced apoptosis in pancreatic β cells is mediated by the endoplasmic reticulum stress pathway
S Oyadomari et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Targeting of the c-Abl tyrosine kinase to mitochondria in endoplasmic reticulum stress-induced Apoptosis
Y Ito et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Targeting of the c-Ab1 tyrosine kinase to mitochondria in the necrotic cell death response to oxidative stress
S Kumar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
F Urano et al.
SCIENCE (2000)
分享论文
