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Lieven Annemans et al.
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Y. Shimizu et al.
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L. A. Houghton et al.
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Distribution pattern of tachykinin NK2 receptors in human colon:: Involvement in the regulation of intestinal motility
Nadia Jaafari et al.
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Johan D. Boot et al.
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Sheila M. Wilhelm et al.
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PJ Hesketh et al.
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H Boutaghou-Cherid et al.
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Pisters
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HY Meltzer et al.
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R de Wit et al.
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S Poli-Bigelli et al.
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RA Blum et al.
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A Holmes et al.
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