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Macrophage CD74 contributes to MIF-induced pulmonary inflammation
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Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart
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Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex
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CD74 induces TAp63 expression leading to B-cell survival
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IL-8 secreted in a macrophage migration-inhibitory factor- and CD74-dependent manner regulates B cell chronic lymphocytic leukemia survival
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Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the Akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activity
H. Lue et al.
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MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment
Juergen Bernhagen et al.
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Inhibition of macrophage migration inhibitory factor or its receptor (CD74) attenuates growth and invasion of DU-145 prostate cancer cells
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CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex
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International uniform response criteria for multiple myeloma
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Cell-surface CD74 initiates a signaling cascade leading to cell proliferation and survival
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Helicobacter pylori CagA-dependent macrophage migration inhibitory factor produced by gastric epithelial cells binds to CD74 and stimulates procarcinogenic events
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Invariant chain transmembrane domain trimerization: A step in MHC class II assembly
AM Dixon et al.
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Establishment of perineural invasion models and analysis of gene expression revealed an invariant chain (CD74) as a possible molecule involved in perineural invasion in pancreatic cancer
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Effective therapy of human lymphoma xenografts with a novel recombinant ribonuclease/anti-CD74 humanized IgG4 antibody immunotoxin
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CD74 is a member of the regulated intramembrane proteolysis-processed protein family
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Anti-CD74 antibody-doxorubicin conjugate, IMMU-110, in a human multiple myeloma xenograft and in monkeys
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CLINICAL CANCER RESEARCH (2005)
Further evidence for increased macrophage migration inhibitory factor expression in prostate cancer
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A gene atlas of the mouse and human protein-encoding transcriptomes
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CD74 is expressed by multiple myeloma and is a promising target for therapy
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Antiproliferative activity of a humanized anti-CD74 monoclonal antibody, hLL1, on B-cell malignancies
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BLOOD (2004)
Resistance to CD95-mediated apoptosis of CD40-activated chronic lymphocytic leukemia B cells is not related to lack of DISC molecules expression
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MIF signal transduction initiated by binding to CD74
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Human cathepsin S, but not cathepsin L, degrades efficiently MHC class II-associated invariant chain in nonprofessional APCs
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Asparagine endopeptidase can initiate the removal of the MHC class II invariant chain chaperone
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Invariant chain-induced B cell differentiation requires intramembrane proteolytic release of the cytosolic domain
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IMMUNITY (2002)
Invariant chain induces B cell maturation in a process that is independent of its chaperonic activity
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