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Ailan Guo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
James Bean et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
Klarisa Rikova et al.
CELL (2007)
Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma
James G. Christensen et al.
MOLECULAR CANCER THERAPEUTICS (2007)
c-Met activation in lung adenocarcinoma tissues: An immunohistochemical analysis
Yu Nakamura et al.
CANCER SCIENCE (2007)
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
Jeffrey A. Engelman et al.
SCIENCE (2007)
An orally available small-molecule inhibitor of c-met, PF-2341066, exhibits cytoreductive antitumor efficacy through antiproliferative and antiangiogenic mechanisms
Helen Y. Zou et al.
CANCER RESEARCH (2007)
Molecular co-expression of the c-Met oncogene and hepatocyte growth factor in primary colon cancer predicts tumor stage and clinical outcome
Udal S. Kammula et al.
CANCER LETTERS (2007)
Lung cancer cell lines harboring MET gene amplification are dependent on met for growth and survival
Bart Lutterbach et al.
CANCER RESEARCH (2007)
Epidermal growth factor receptor plays a significant role in hepatocyte growth factor mediated biological responses in mammary epithelial cells
Alyssa R. Bonine-Summers et al.
CANCER BIOLOGY & THERAPY (2007)
Involvement of c-Met/hepatocyte growth factor pathway in cholangiocarcinoma cell invasion and its therapeutic inhibition with small interfering RNA specific for c-Met
Kawin Leelawat et al.
JOURNAL OF SURGICAL RESEARCH (2006)
A novel one-armed anti-c-met antibody inhibits glioblastoma growth in vivo
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CLINICAL CANCER RESEARCH (2006)
Met receptor signaling: A key effector in esophageal adenocarcinoma
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CLINICAL CANCER RESEARCH (2006)
Identification of genes that modulate sensitivity of U373MG glioblastoma cells to cis-platinum
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ANTI-CANCER DRUGS (2006)
The clinical value of hepatocyte growth factor and its receptor - c-met for liver cancer patients with hepatectorny
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DIGESTIVE AND LIVER DISEASE (2006)
Regulatory role of c-Met in insulin-like growth factor-I receptor-mediated migration and invasion of human pancreatic carcinoma cells
Todd W. Bauer et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Involvement of hepatocyte growth factor in the development of bone metastasis of a mouse mammary cancer cell line, BALB/c-MC
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BONE (2006)
Structural basis of hepatocyte growth factor/scatter factor and MET signalling
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenografts
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CLINICAL CANCER RESEARCH (2006)
Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Fully human monoclonal antibodies to hepatocyte growth factor with therapeutic potential against hepatocyte growth factor/c-Met-dependent human tumors
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CANCER RESEARCH (2006)
Somatic mutations lead to an oncogenic deletion of Met in lung cancer
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CANCER RESEARCH (2006)
Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis
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NEURO-ONCOLOGY (2005)
Recent progress in targeting the Raf/MEK/ERK pathway with inhibitors in cancer drug discovery
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CURRENT OPINION IN PHARMACOLOGY (2005)
c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention
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CANCER LETTERS (2005)
Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis
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CANCER RESEARCH (2005)
Expression of the c-Met in advanced epithelial ovarian cancer and its prognostic significance
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INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER (2005)
Targeting the c-Met pathway potentiates glioblastoma responses to γ-radiation
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CLINICAL CANCER RESEARCH (2005)
MET receptor tyrosine kinase sequence alterations in differentiated thyroid carcinoma
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AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2005)
HGF converts ErbB2/Neu epithelial morphogenesis to cell invasion
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MOLECULAR BIOLOGY OF THE CELL (2005)
Hepatocyte growth factor, its receptor, and their potential value in cancer therapies
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CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2005)
Suppression of tumor growth, invasion and angiogenesis of human gastric cancer by adenovirus-mediated expression of NK4
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JOURNAL OF GENE MEDICINE (2004)
Activation of c-Met (hepatocyte growth factor receptor) in human gastric cancer tissue
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CANCER SCIENCE (2004)
Targeting the HGF/SF receptor c-met using a hammerhead ribozyme transgene reduces in vitro invasion and migration in prostate cancer cells
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PROSTATE (2004)
Genetic and expression profiles of squamous cell carcinoma of the head and neck correlate with cisplatin sensitivity and resistance in cell lines and patients
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CLINICAL CANCER RESEARCH (2004)
Met, metastasis, motility and more
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NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
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CANCER CELL (2003)
Overexpression of the c-Met/HGF receptor and its prognostic significance in uterine cervix carcinomas
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GYNECOLOGIC ONCOLOGY (2003)
CD44 is required for two consecutive steps in HGF/c-Met signaling
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GENES & DEVELOPMENT (2002)
The Semaphorin 4D receptor controls invasive growth by coupling with Met
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NATURE CELL BIOLOGY (2002)
Hepatocyte growth factor inhibits anoikis in head and neck squamous cell carcinoma cells by activation of ERK and Akt signaling independent of NFκB
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
A mechanism of cell survival: Sequestration of Fas by the HGF receptor Met
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MOLECULAR CELL (2002)
A signaling adapter function for α6β4 integrin in the control of HGF-dependent invasive growth
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CELL (2001)
Role of HGF/c-met system in invasion and metastasis of oral squamous cell carcinoma cells in vitro and its clinical significance
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INTERNATIONAL JOURNAL OF CANCER (2001)
The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair
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MOLECULAR AND CELLULAR BIOLOGY (2001)
Hepatocyte growth factor induces colonic cancer cell invasiveness via enhanced motility and protease overproduction. Evidence for PI3 kinase and PKC involvement
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CARCINOGENESIS (2001)
Hepatocyte growth factor: Renotropic role and potential therapeutics for renal diseases
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KIDNEY INTERNATIONAL (2001)
Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice
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JOURNAL OF CELL BIOLOGY (2001)
Expression of the hepatocyte growth factor/c-Met pathway is increased at the cancer front in breast carcinoma
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PATHOLOGY INTERNATIONAL (2001)
Myocardial protection from ischemia/reperfusion injury by endogenous and exogenous HGF
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JOURNAL OF CLINICAL INVESTIGATION (2000)
A novel germ line juxtamembrane Met mutation in human gastric cancer
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ONCOGENE (2000)
Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses
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JOURNAL OF CELL BIOLOGY (2000)
Somatic mutations of the MET oncogene are selected during metastatic spread of human HNSC carcinomas
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ONCOGENE (2000)
Sustained recruitment of phospholipase C-γ to Gab1 is required for HGF-induced branching tubulogenesis
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ONCOGENE (2000)