相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Mitochondrial DNA deletions in Alzheimer's brains: A review
Nicole R. Phillips et al.
ALZHEIMERS & DEMENTIA (2014)
Epigenetic regulation of the tissue-specific expression of human UDP-glucuronosyltransferase (UGT) 1A10
Shingo Oda et al.
BIOCHEMICAL PHARMACOLOGY (2014)
Integrating DNA methylation dynamics into a framework for understanding epigenetic codes
Keith E. Szulwach et al.
BIOESSAYS (2014)
Epigenetic choreography of stem cells: the DNA demethylation episode of development
Swayamsiddha Kar et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2014)
Histone Deacetylase Inhibitors with Enhanced Enzymatic Inhibition Effects and Potent in vitro and in vivo Antitumor Activities
Lei Zhang et al.
CHEMMEDCHEM (2014)
Epigenetic Drugs in Cognitive Disorders
Jacob Peedicayil
CURRENT PHARMACEUTICAL DESIGN (2014)
Chromatin remodeling by the small RNA machinery in mammalian cells
Long-Cheng Li
EPIGENETICS (2014)
High-density array analysis of DNA methylation in Tamoxifen-resistant breast cancer cell lines
Kristin E. Williams et al.
EPIGENETICS (2014)
RNA-mediated gene activation
Alan L. Jiao et al.
EPIGENETICS (2014)
Involvement of α7 nAChR Signaling Cascade in Epigallocatechin Gallate Suppression of β-Amyloid-Induced Apoptotic Cortical Neuronal Insults
Xijing Zhang et al.
MOLECULAR NEUROBIOLOGY (2014)
Rare autosomal copy number variations in early-onset familial Alzheimer's disease
B. V. Hooli et al.
MOLECULAR PSYCHIATRY (2014)
Epigenetically regulated microRNAs in Alzheimer's disease
Daniel L. Van den Hove et al.
NEUROBIOLOGY OF AGING (2014)
High doses of the histone deacetylase inhibitor sodium butyrate trigger a stress-like response
Humberto Gagliano et al.
NEUROPHARMACOLOGY (2014)
EPIGENETIC REGULATION IN NEURODEVELOPMENT AND NEURODEGENERATIVE DISEASES
K. Gapp et al.
NEUROSCIENCE (2014)
Therapeutic Potential of Turmeric in Alzheimer's Disease: Curcumin or Curcuminoids?
Touqeer Ahmed et al.
PHYTOTHERAPY RESEARCH (2014)
Epigenetic Changes in Gene Expression for Drug-Metabolizing Enzymes and Transporters
In-Wha Kim et al.
PHARMACOTHERAPY (2014)
Reversible epigenetic histone modifications and Bdnf expression in neurons with aging and from a mouse model of Alzheimer's disease
Michael P. Walker et al.
AGE (2013)
Epigenetic mechanisms in Alzheimer's disease: Implications for pathogenesis and therapy
Jun Wang et al.
AGEING RESEARCH REVIEWS (2013)
The Clinical and Economic Burden of Newly Diagnosed Alzheimer's Disease in a Medicare Advantage Population
Brandon T. Suehs et al.
AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS (2013)
The Potential of HDAC Inhibitors as Cognitive Enhancers
Johannes Graeff et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 53, 2013 (2013)
Ketamine and imipramine in the nucleus accumbens regulate histone deacetylation induced by maternal deprivation and are critical for associated behaviors
Gislaine Z. Reus et al.
BEHAVIOURAL BRAIN RESEARCH (2013)
Silencing of the P2X7 receptor enhances amyloid-β phagocytosis by microglia
Jiong Ni et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Roles of long noncoding RNAs in brain development, functional diversification and neurodegenerative diseases
Ping Wu et al.
BRAIN RESEARCH BULLETIN (2013)
Curcumin, an Active Constiuent of the Ancient Medicinal Herb Curcuma longa L.: Some Uses and the Establishment and Biological Basis of Medical Efficacy
Jeffrey M. Witkin et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2013)
The LRRK2 R1628P Variant Plays a Protective Role in Han Chinese Population with Alzheimer's Disease
Hong-Lei Li et al.
CNS NEUROSCIENCE & THERAPEUTICS (2013)
Medicinal Chemistry of the Epigenetic Diet and Caloric Restriction
S. Martin et al.
CURRENT MEDICINAL CHEMISTRY (2013)
Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease
Nambirajan Govindarajan et al.
EMBO MOLECULAR MEDICINE (2013)
Post-Transcriptional Controls by Ribonucleoprotein Complexes in the Acquisition of Drug Resistance
Hoin Kang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Presenilin-1 Mutations in Alzheimer's Disease: An Update on Genotype-Phenotype Relationships
A. J. Larner
JOURNAL OF ALZHEIMERS DISEASE (2013)
Chromosome 21-derived microRNAs provide an etiological basis for aberrant protein expression in human down syndrome brains (vol 285, pg 1529, 2010)
Donald E. Kuhn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Effects of small interfering RNA targeting sphingosine kinase-1 gene on the animal model of Alzheimer's disease
Yuan Zhang et al.
JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES (2013)
The role of mitochondrial DNA mutations and free radicals in disease and ageing
M. Lagouge et al.
JOURNAL OF INTERNAL MEDICINE (2013)
Quinazolin-4-one Derivatives as Selective Histone Deacetylase-6 Inhibitors for the Treatment of Alzheimer's Disease
Chao-Wu Yu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Toll-like receptor 9 promoter polymorphism is associated with decreased risk of Alzheimer's disease in Han Chinese
Ying-Li Wang et al.
JOURNAL OF NEUROINFLAMMATION (2013)
Differential Induction of Apoptosis and Senescence by the DNA Methyltransferase Inhibitors 5-Azacytidine and 5-Aza-2′-Deoxycytidine in Solid Tumor Cells
Sascha Venturelli et al.
MOLECULAR CANCER THERAPEUTICS (2013)
Epigenetic mechanisms in multiple sclerosis: implications for pathogenesis and treatment
Jimmy L. Huynh et al.
LANCET NEUROLOGY (2013)
miR-26a promotes neurite outgrowth by repressing PTEN expression
Baoguo Li et al.
MOLECULAR MEDICINE REPORTS (2013)
Chromatin proteins and modifications as drug targets
Kristian Helin et al.
NATURE (2013)
Histone lysine demethylases as targets for anticancer therapy
Jonas W. Hojfeldt et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients
Leonidas Chouliaras et al.
NEUROBIOLOGY OF AGING (2013)
Levetiracetam resistance: Synaptic signatures & corresponding promoter SNPs in epileptic hippocampi
Tanja Grimminger et al.
NEUROBIOLOGY OF DISEASE (2013)
Free and nanoencapsulated curcumin suppress β-amyloid-induced cognitive impairments in rats: Involvement of BDNF and Akt/GSK-3β signaling pathway
Juliana B. Hoppe et al.
NEUROBIOLOGY OF LEARNING AND MEMORY (2013)
Chromatin Modifications Associated with DNA Double-strand Breaks Repair as Potential Targets for Neurological Diseases
Camille Brochier et al.
NEUROTHERAPEUTICS (2013)
Epigenetics Components of Aging in the Central Nervous System
Yue-Qiang Zhao et al.
NEUROTHERAPEUTICS (2013)
Epigenetics and ncRNAs in Brain Function and Disease: Mechanisms and Prospects for Therapy
Miguel A. Varela et al.
NEUROTHERAPEUTICS (2013)
Natural Compounds May Open New Routes to Treatment of Amyloid Diseases
Jan Bieschke
NEUROTHERAPEUTICS (2013)
Resveratrol Inhibits β-Amyloid-Induced Neuronal Apoptosis through Regulation of SIRT1-ROCK1 Signaling Pathway
Xiaowen Feng et al.
PLOS ONE (2013)
Linking Protective GAB2 Variants, Increased Cortical GAB2 Expression and Decreased Alzheimer's Disease Pathology
Fanggeng Zou et al.
PLOS ONE (2013)
SAHA Enhances Synaptic Function and Plasticity In Vitro but Has Limited Brain Availability In Vivo and Does Not Impact Cognition
Jesse E. Hanson et al.
PLOS ONE (2013)
Pharmacological Reversal of Histone Methylation Presensitizes Pancreatic Cancer Cells to Nucleoside Drugs: In Vitro Optimization and Novel Nanoparticle Delivery Studies
Sau Wai Hung et al.
PLOS ONE (2013)
A Selective HDAC 1/2 Inhibitor Modulates Chromatin and Gene Expression in Brain and Alters Mouse Behavior in Two Mood-Related Tests
Frederick A. Schroeder et al.
PLOS ONE (2013)
Epigenetics: A novel therapeutic approach for the treatment of Alzheimer's disease
Lina Adwan et al.
PHARMACOLOGY & THERAPEUTICS (2013)
RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain
Sarah Picaud et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Common non-epigenetic drugs as epigenetic modulators
Joern Loetsch et al.
TRENDS IN MOLECULAR MEDICINE (2013)
Identification and function of long non-coding RNA
Carl Emst et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2013)
Dynamic changes of the epigenetic landscape during cellular differentiation
Silvia Dambacher et al.
EPIGENOMICS (2013)
Epigenetic effects of green tea polyphenols in cancer
Susanne M. Henning et al.
EPIGENOMICS (2013)
Genomic and Epigenomic Insights into Nutrition and Brain Disorders
Margaret Joy Dauncey
NUTRIENTS (2013)
Human umbilical cord mesenchymal stem cell-derived neuron-like cells rescue memory deficits and reduce amyloid-beta deposition in an AβPP/PS1 transgenic mouse model
Hui Yang et al.
STEM CELL RESEARCH & THERAPY (2013)
Schistosoma mansoni Sirtuins: Characterization and Potential as Chemotherapeutic Targets
Julien Lancelot et al.
PLOS NEGLECTED TROPICAL DISEASES (2013)
DNA methylation in interleukin-11 predicts clinical response to antidepressants in GENDEP
T. R. Powell et al.
TRANSLATIONAL PSYCHIATRY (2013)
Chromatin-based epigenetics of adult subventricular zone neural stem cells
Gabriel Gonzales-Roybal et al.
Frontiers in Genetics (2013)
DNA Methylation: A Mechanism for Embedding Early Life Experiences in the Genome
Moshe Szyf et al.
CHILD DEVELOPMENT (2013)
The histone deacetylase inhibitor, romidepsin, suppresses cellular immune functions of cutaneous T-cell lymphoma patients
Michael J. Kelly-Sell et al.
AMERICAN JOURNAL OF HEMATOLOGY (2012)
NDM29, a RNA polymerase III-dependent non coding RNA, promotes amyloidogenic processing of APP and amyloid β secretion
Sara Massone et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)
MicroRNA-195 downregulates Alzheimer's disease amyloid-β production by targeting BACE1
Hong-Can Zhu et al.
BRAIN RESEARCH BULLETIN (2012)
Pharmacogenomics of Central Nervous System (CNS) Drugs
Ramon Cacabelos
DRUG DEVELOPMENT RESEARCH (2012)
Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease
Ana Ricobaraza et al.
HIPPOCAMPUS (2012)
Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression
Lucas E. Rossi et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2012)
An Essential Role for Histone Deacetylase 4 in Synaptic Plasticity and Memory Formation
Mi-Sung Kim et al.
JOURNAL OF NEUROSCIENCE (2012)
MicroRNAs in brain development and degeneration
Ana-Maria Enciu et al.
MOLECULAR BIOLOGY REPORTS (2012)
Trials with 'epigenetic' drugs: An update
Angela Nebbioso et al.
MOLECULAR ONCOLOGY (2012)
An epigenetic blockade of cognitive functions in the neurodegenerating brain
Johannes Graeff et al.
NATURE (2012)
Epigenetic protein families: a new frontier for drug discovery
Cheryl H. Arrowsmith et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice
Wei Liu et al.
NEUROBIOLOGY OF AGING (2012)
Increased EID1 nuclear translocation impairs synaptic plasticity and memory function associated with pathogenesis of Alzheimer's disease
Rugao Liu et al.
NEUROBIOLOGY OF DISEASE (2012)
MicroRNAs in neurodegenerative diseases and their therapeutic potential
Eunsung Junn et al.
PHARMACOLOGY & THERAPEUTICS (2012)
Targeted proteomics for quantification of histone acetylation in Alzheimer's disease
Kangling Zhang et al.
PROTEOMICS (2012)
The miR-124 regulates the expression of BACE1/β-secretase correlated with cell death in Alzheimer's disease
Marong Fang et al.
TOXICOLOGY LETTERS (2012)
Epigenetic histone acetylation and deacetylation mechanisms in experimental models of neurodegenerative disorders
Zacharoula Konsoula et al.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2012)
Epigenetic Mechanisms and Therapeutic Perspectives for Neurodevelopmental Disorders
Takeo Kubota et al.
PHARMACEUTICALS (2012)
Patterns of microRNA expression in normal and early Alzheimer's disease human temporal cortex: white matter versus gray matter
Wang-Xia Wang et al.
ACTA NEUROPATHOLOGICA (2011)
MicroRNA-101 downregulates Alzheimer's amyloid-β precursor protein levels in human cell cultures and is differentially expressed
Justin M. Long et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
miR-29c regulates BACE1 protein expression
Yuanyuan Zong et al.
BRAIN RESEARCH (2011)
Genomics and Pharmacogenomics of Dementia
Ramon Cacabelos et al.
CNS NEUROSCIENCE & THERAPEUTICS (2011)
Advances in Epigenetics and Epigenomics for Neurodegenerative Diseases
Irfan A. Qureshi et al.
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2011)
Green Tea Epigallocatechin-3-Gallate (EGCG) and Other Flavonoids Reduce Alzheimer's Amyloid-Induced Mitochondrial Dysfunction
Natasa Dragicevic et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Sodium Butyrate Improves Memory Function in an Alzheimer's Disease Mouse Model When Administered at an Advanced Stage of Disease Progression
Nambirajan Govindarajan et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
In vivo regulation of amyloid precursor protein neuronal splicing by microRNAs
Pascal Smith et al.
JOURNAL OF NEUROCHEMISTRY (2011)
MicroRNA-137/181c Regulates Serine Palmitoyltransferase and In Turn Amyloid β, Novel Targets in Sporadic Alzheimer's Disease
Hirosha Geekiyanage et al.
JOURNAL OF NEUROSCIENCE (2011)
DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models
Andrea Fuso et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2011)
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
Lydia Alvarez-Erviti et al.
NATURE BIOTECHNOLOGY (2011)
Epigenetic mechanisms in Alzheimer's disease
Diego Mastroeni et al.
NEUROBIOLOGY OF AGING (2011)
17A, a novel non-coding RNA, regulates GABA B alternative splicing and signaling in response to inflammatory stimuli and in Alzheimer disease
Sara Massone et al.
NEUROBIOLOGY OF DISEASE (2011)
The path to epigenetic treatment of memory disorders
Mikael A. Mikaelsson et al.
NEUROBIOLOGY OF LEARNING AND MEMORY (2011)
Curcumin Attenuates Aluminum-Induced Oxidative Stress and Mitochondrial Dysfunction in Rat Brain
Pooja Khanna Sood et al.
NEUROTOXICITY RESEARCH (2011)
Targeting HDACs: A Promising Therapy for Alzheimer's Disease
Ke Xu et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2011)
Resveratrol Acts Not through Anti-Aggregative Pathways but Mainly via Its Scavenging Properties against Aβ and Aβ-Metal Complexes Toxicity
Alberto Granzotto et al.
PLOS ONE (2011)
MicroRNA regulation of homeostatic synaptic plasticity
Jonathan E. Cohen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
A complex crosstalk between polymorphic microRNA target sites and AD prognosis
Bibekanand Mallick et al.
RNA BIOLOGY (2011)
miR-107 Regulates Granulin/Progranulin with Implications for Traumatic Brain Injury and Neurodegenerative Disease
Wang-Xia Wang et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Effects of histone deacetylase inhibitor Trichostatin A on epigenetic changes and transcriptional activation of Bdnf promoter 1 by rat hippocampal neurons
Feng Tian et al.
NEUROPROTECTIVE AGENTS (2010)
Differential epigenetic regulation of BDNF and NT-3 genes by trichostatin A and 5-aza-2′-deoxycytidine in Neuro-2a cells
Naoki Ishimaru et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Increased expression of cholesterol transporter ABCA1 is highly correlated with severity of dementia in AD hippocampus
Afia Akram et al.
BRAIN RESEARCH (2010)
被撤回的出版物: SIRT1 Suppresses β-Amyloid Production by Activating the α-Secretase Gene ADAM10 (Retracted article. See vol. 158, pg. 959, 2014)
Gizem Donmez et al.
CELL (2010)
The clinical development of histone deacetylase inhibitors as targeted anticancer drugs
Paul A. Marks
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2010)
Dynamic changes in the human methylome during differentiation
Louise Laurent et al.
GENOME RESEARCH (2010)
Evidence Linking Genetics, Environment, and Epigenetics to Impaired DNA Repair in Alzheimer's Disease
Fabio Coppede et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Histone Methylation Regulates Memory Formation
Swati Gupta et al.
JOURNAL OF NEUROSCIENCE (2010)
Epigenetic modifications as therapeutic targets
Theresa K. Kelly et al.
NATURE BIOTECHNOLOGY (2010)
Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease
Mark Kilgore et al.
NEUROPSYCHOPHARMACOLOGY (2010)
Valproic acid stimulates clusterin expression in human astrocytes: Implications for Alzheimer's disease
Tapio Nuutinen et al.
NEUROSCIENCE LETTERS (2010)
Epigenetic regulation in the pathophysiology of Alzheimer's disease
Leonidas Chouliaras et al.
PROGRESS IN NEUROBIOLOGY (2010)
Apolipoprotein E and central nervous system disorders: Reviews of clinical findings
Masatoshi Takeda et al.
PSYCHIATRY AND CLINICAL NEUROSCIENCES (2010)
Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice
Shahaf Peleg et al.
SCIENCE (2010)
Small-molecule chromatin-modifying agents: therapeutic applications
Antonello Mai
EPIGENOMICS (2010)
Evidence for natural antisense transcript-mediated inhibition of microRNA function
Mohammad Ali Faghihi et al.
GENOME BIOLOGY (2010)
Future Trends in the Pharmacogenomics of Brain Disorders and Dementia: Influence of APOE and CYP2D6 Variants
Ramon Cacabelos et al.
PHARMACEUTICALS (2010)
Epigenetic changes related to beta-amyloid-implications for Alzheimer's disease
Christina Unger Lithner et al.
Alzheimers & Dementia (2009)
The Biology of Chromatin Remodeling Complexes
Cedric R. Clapier et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
Pharmacogenomics and therapeutic strategies for dementia
Ramon Cacabelos
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS (2009)
Dysregulation of Histone Acetylation in the APP/PS1 Mouse Model of Alzheimer's Disease
Yitshak I. Francis et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
MicroRNA-298 and MicroRNA-328 Regulate Expression of Mouse β-Amyloid Precursor Protein-converting Enzyme 1
Vincent Boissonneault et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Histone Deacetylase Inhibitors: Potential in Cancer Therapy
P. A. Marks et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2009)
Sirtuin 1 Reduction Parallels the Accumulation of Tau in Alzheimer Disease
Carl Julien et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2009)
Protein Phosphatase 1 Regulates the Histone Code for Long-Term Memory
Kyoko Koshibu et al.
JOURNAL OF NEUROSCIENCE (2009)
HDAC2 negatively regulates memory formation and synaptic plasticity
Ji-Song Guan et al.
NATURE (2009)
Multiple roles of HDAC inhibition in neurodegenerative conditions
De-Maw Chuang et al.
TRENDS IN NEUROSCIENCES (2009)
Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes
Na-Hye Myung et al.
AGE (2008)
P3-260: Epigenetic modification in a monozygotic twin with Alzheimer's disease
Hoon Ryu et al.
Alzheimers & Dementia (2008)
Pharmacogenomics and therapeutic prospects in dementia
Ramon Cacabelos
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE (2008)
Valproic acid inhibits Aβ production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models
Hong Qing et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Histone deacetylase 6 interacts with the microtubule-associated protein tau
Huiping Ding et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau
Kim N. Green et al.
JOURNAL OF NEUROSCIENCE (2008)
The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of β-site amyloid precursor protein-cleaving enzyme 1
Wang-Xia Wang et al.
JOURNAL OF NEUROSCIENCE (2008)
Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase
Mohammad Ali Faghihi et al.
NATURE MEDICINE (2008)
Age-Specific Epigenetic Drift in Late-Onset Alzheimer's Disease
Sun-Chong Wang et al.
PLOS ONE (2008)
Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/β-secretase expression
Sebastien S. Hebert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Structure-activity studies on suramin analogues as inhibitors of NAD+-dependent histone deacetylases (Sirtuins)
Johannes Trapp et al.
CHEMMEDCHEM (2007)
Recovery of learning and memory is associated with chromatin remodelling
Andre Fischer et al.
NATURE (2007)
Pharmacogenetic basis for therapeutic optimization in Alzheimer's disease
Ramon Cacabelos
MOLECULAR DIAGNOSIS & THERAPY (2007)
Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database
Lars Bertram et al.
NATURE GENETICS (2007)
Pharmacogenomics and therapeutic prospects in Alzheimer's disease
R Cacabelos
EXPERT OPINION ON PHARMACOTHERAPY (2005)
Calorie restriction, SIRT1 and metabolism: Understanding longevity
L Bordone et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Phenylbutyrate increases SMN gene expression in spinal muscular atrophy patients
C Brahe et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2005)
Epigenetic mechanisms in memory formation
JM Levenson et al.
NATURE REVIEWS NEUROSCIENCE (2005)
Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′-deoxycytidine (decitabine) in hematopoietic malignancies
JPJ Issa et al.
BLOOD (2004)
Regulation of histone acetylation during memory formation in the hippocampus
JM Levenson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Lithium, a common drug for bipolar disorder treatment, regulates amyloid-β precursor protein processing
Y Su et al.
BIOCHEMISTRY (2004)
The application of functional genomics to Alzheimer's disease
R Cacabelos
PHARMACOGENOMICS (2003)
Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation
SJ Haggarty et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice
J Trasler et al.
CARCINOGENESIS (2003)