4.5 Review

Discovery and design of carbohydrate-based therapeutics

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biotechnology & Applied Microbiology

Carbohydrate vaccines: developing sweet solutions to sticky situations?

Rena D. Astronomo et al.

NATURE REVIEWS DRUG DISCOVERY (2010)

Article Chemistry, Medicinal

Strategies in Developing Promising Histone Deacetylase Inhibitors

Lei Zhang et al.

MEDICINAL RESEARCH REVIEWS (2010)

Review Chemistry, Multidisciplinary

The beta-D-Glucose Scaffold as a beta-Turn Mimetic

Ralph F. Hirschmann et al.

ACCOUNTS OF CHEMICAL RESEARCH (2009)

Article Biochemistry & Molecular Biology

A Cystic Fibrosis Respiratory Epithelial Cell Chronically Treated by Miglustat Acquires a Non-Cystic Fibrosis-Like Phenotype

Caroline Norez et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2009)

Review Chemistry, Multidisciplinary

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

Ellen M. Sletten et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)

Review Chemistry, Multidisciplinary

New Principles for Glycoside-Bond Formation

Xiangming Zhu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)

Article Biochemistry & Molecular Biology

Selective cytotoxicity of a bicyclic Ras inhibitor in cancer cells expressing K-RaSG13D

Alessandro Palmioli et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)

Review Biochemistry & Molecular Biology

Olefin Metathesis for Site-Selective Protein Modification

Yuya A. Lin et al.

CHEMBIOCHEM (2009)

Review Chemistry, Multidisciplinary

Immunotherapy for cancer: synthetic carbohydrate-based vaccines

Therese Buskas et al.

CHEMICAL COMMUNICATIONS (2009)

Article Chemistry, Multidisciplinary

STICS: surface-tethered iterative carbohydrate synthesis

Papapida Pornsuriyasak et al.

CHEMICAL COMMUNICATIONS (2009)

Review Chemistry, Multidisciplinary

Glycoprotein Synthesis: An Update

David P. Gamblin et al.

CHEMICAL REVIEWS (2009)

Review Chemistry, Medicinal

Carbohydrates: A Frontier in Medicinal Chemistry

Pierre Stallforth et al.

JOURNAL OF MEDICINAL CHEMISTRY (2009)

Article Chemistry, Medicinal

Glycolipids and Benzylammonium Lipids as Novel Antisepsis Agents: Synthesis and Biological Characterization

Matteo Piazza et al.

JOURNAL OF MEDICINAL CHEMISTRY (2009)

Review Chemistry, Multidisciplinary

Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research

Thomas J. Boltje et al.

NATURE CHEMISTRY (2009)

Review Biotechnology & Applied Microbiology

From carbohydrate leads to glycomimetic drugs

Beat Ernst et al.

NATURE REVIEWS DRUG DISCOVERY (2009)

Article Plant Sciences

Suppressive effects of swainsonine on C6 glioma cell in vitro and in vivo

Ji-Yuan Sun et al.

PHYTOMEDICINE (2009)

Review Pharmacology & Pharmacy

Siglecs as targets for therapy in immune-cell-mediated disease

Mary K. O'Reilly et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2009)

Review Biochemistry & Molecular Biology

Glycosyltransferases: Structures, functions, and mechanisms

L. L. Lairson et al.

ANNUAL REVIEW OF BIOCHEMISTRY (2008)

Review Oncology

Glycoconjugates in cancer therapy

Laura Cipolla et al.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Fructose-fused γ-butyrolactones and lactams, synthesis and biological evaluation as GABA receptor ligands

Ana C. Araujo et al.

CARBOHYDRATE RESEARCH (2008)

Review Chemistry, Multidisciplinary

Automated oligosaccharide synthesis

Peter H. Seeberger

CHEMICAL SOCIETY REVIEWS (2008)

Review Chemistry, Multidisciplinary

Chemoselective modification of proteins: hitting the target

Isaac S. Carrico

CHEMICAL SOCIETY REVIEWS (2008)

Review Chemistry, Organic

Re LPS biogenetic pathway: Enzyme characterisation and synthetic efforts towards inhibitors

Laura Cipolla et al.

CURRENT ORGANIC CHEMISTRY (2008)

Review Chemistry, Medicinal

Recent developments in synthetic oligosaccharide-based bacterial vaccines

Vince Pozsgay

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2008)

Article Chemistry, Medicinal

Current Understanding on Biosynthesis of Microbial Polysaccharides

Peng Wang et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2008)

Article Chemistry, Organic

Synthesis and biological evaluation of novel rigid 1,4-benzodiazepine-2,5-dione chimeric scaffolds

Ana C. Araujo et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2008)

Review Immunology

Protein-glycan interactions in the control of innate and adaptive immune responses

Yvette van Kooyk et al.

NATURE IMMUNOLOGY (2008)

Article Biochemistry & Molecular Biology

Exploring the structural diversity of mammalian carbohydrates (Glycospace) by statistical databank analysis

Daniel B. Werz et al.

ACS CHEMICAL BIOLOGY (2007)

Review Immunology

Recent advances in antigen processing and presentation

Peter E. Jensen

NATURE IMMUNOLOGY (2007)

Article Biochemistry & Molecular Biology

Robust immune responses elicited by a fully synthetic three-component vaccine

Sampat Ingale et al.

NATURE CHEMICAL BIOLOGY (2007)

Review Biochemistry & Molecular Biology

Active-site-specific chaperone therapy for Fabry disease

Jian-Qiang Fan et al.

FEBS JOURNAL (2007)

Article Chemistry, Organic

Peptidomimetics, glycomimetics and scaffolds from carbohydrate building blocks

Paul V. Murphy

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2007)

Article Clinical Neurology

Miglustat for treatment of Niemann-Pick C disease: a randomised controlled study

Marc C. Patterson et al.

LANCET NEUROLOGY (2007)

Article Biochemistry & Molecular Biology

Human MD-2 discrimination of meningococcal lipid A structures and activation of TLR4

Shanta M. Zimmer et al.

GLYCOBIOLOGY (2007)

Article Biochemistry & Molecular Biology

Potentiation of fibroblast growth factor activity by synthetic heparin oligosaccharide glycodendrimers

Jose L. de Paz et al.

CHEMISTRY & BIOLOGY (2007)

Article Multidisciplinary Sciences

Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa

Umeharu Ohto et al.

SCIENCE (2007)

Review Biochemistry & Molecular Biology

Evolution of carbohydrate antigens - microbial forces shaping host glycomes?

Joseph R. Bishop et al.

GLYCOBIOLOGY (2007)

Review Chemistry, Multidisciplinary

Synthesis and conformational and biological aspects of carbasugars

Odon Arjona et al.

CHEMICAL REVIEWS (2007)

Review Multidisciplinary Sciences

Chemical glycosylation in the synthesis of glycoconjugate antitumour vaccines

Danica P. Galonic et al.

NATURE (2007)

Review Multidisciplinary Sciences

Synthesis and medical applications of oligosaccharides

Peter H. Seeberger et al.

NATURE (2007)

Article Immunology

Vaccines in the era of genomics: The pneumococcal challenge

Michele Anne Barocchi et al.

VACCINE (2007)

Article Multidisciplinary Sciences

Regioselective one-pot protection of carbohydrates

Cheng-Chung Wang et al.

NATURE (2007)

Article Chemistry, Organic

Synthesis of scaffolds with glycomimetic structures

C. Gravier-Pelletier et al.

CURRENT ORGANIC SYNTHESIS (2007)

Review Immunology

Siglecs and their roles in the immune system

Paul R. Crocker et al.

NATURE REVIEWS IMMUNOLOGY (2007)

Review Chemistry, Medicinal

Carbohydrates as scaffolds in drug discovery

Wirn Meutermans et al.

CHEMMEDCHEM (2006)

Review Biochemistry & Molecular Biology

Engineering of glycosidases and glycosyltransferases

Susan M. Hancock et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2006)

Review Biochemistry & Molecular Biology

Glycosylation in cellular mechanisms of health and disease

Kazuaki Ohtsubo et al.

Correction Genetics & Heredity

Genetic defects in the human glycome (vol 7, pg 537, 2006)

Hudson H. Freeze

NATURE REVIEWS GENETICS (2006)

Review Chemistry, Organic

Glycosyl hydrolases and glycosyltransferases in the synthesis of oligosaccharides

Antonio Trincone et al.

CURRENT ORGANIC CHEMISTRY (2006)

Review Genetics & Heredity

Genetic defects in the human glycome

Hudson H. Freeze

NATURE REVIEWS GENETICS (2006)

Review Biochemistry & Molecular Biology

Carbohydrate based vaccines

Johannes F. G. Vliegenthart

FEBS LETTERS (2006)

Article Biochemistry & Molecular Biology

Bicyclic carbohydrate-derived scaffolds for combinatorial libraries

G Cervi et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2006)

Review Biochemistry & Molecular Biology

Sweet spots in functional glycomics

JC Paulson et al.

NATURE CHEMICAL BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Carbohydrate-based molecular scaffolding

Ingrid Velter et al.

JOURNAL OF CARBOHYDRATE CHEMISTRY (2006)

Article Multidisciplinary Sciences

Carbohydrate microarray for profiling the antibodies interacting with Globo H tumor antigen

CY Huang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Hematology

Guidance on the use of miglustat for treating patients with type 1 Gaucher disease

NJ Weinreb et al.

AMERICAN JOURNAL OF HEMATOLOGY (2005)

Review Biochemical Research Methods

Glycomics: an integrated systems approach to structure-function relationships of glycans

R Raman et al.

NATURE METHODS (2005)

Article Cell Biology

Carbohydrate vaccines as immunotherapy for cancer

SF Slovin et al.

IMMUNOLOGY AND CELL BIOLOGY (2005)

Review Biotechnology & Applied Microbiology

Glycans in cancer and inflammation. Potential for therapeutics and diagnostics

DH Dube et al.

NATURE REVIEWS DRUG DISCOVERY (2005)

Article Chemistry, Multidisciplinary

Carbohydrates as the next frontier in pharmaceutical research

DB Werz et al.

CHEMISTRY-A EUROPEAN JOURNAL (2005)

Article Chemistry, Organic

Synthesis of selected LeY and KH-1 analogues:: A medicinal chemistry approach to vaccine optimization

MK Spassova et al.

JOURNAL OF ORGANIC CHEMISTRY (2005)

Article Chemistry, Organic

Carbohydrate scaffolds for the production of bioactive compounds

L Cipolla et al.

CURRENT ORGANIC SYNTHESIS (2005)

Review Biochemistry & Molecular Biology

Structural insights into biological roles of protein-glycosaminoglycan interactions

R Raman et al.

CHEMISTRY & BIOLOGY (2005)

Article Chemistry, Medicinal

Synthesis and immunological properties of N-modified GM3 antigens as therapeutic cancer vaccines

YB Pan et al.

JOURNAL OF MEDICINAL CHEMISTRY (2005)

Review Multidisciplinary Sciences

How viruses enter animal cells

AE Smith et al.

SCIENCE (2004)

Article Multidisciplinary Sciences

A synthetic conjugate polysaccharide vaccine against Haemophilus influenzae type b

V Verez-Bencomo et al.

SCIENCE (2004)

Review Biochemical Research Methods

Carbohydrate diversity:: synthesis of glycoconjugates and complex carbohydrates

A Höleman et al.

CURRENT OPINION IN BIOTECHNOLOGY (2004)

Review Biochemistry & Molecular Biology

Antigenic glycans in parasitic infections: implications for vaccines and diagnostics

AK Nyame et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2004)

Review Chemistry, Multidisciplinary

A synthetic antithrombin III binding pentasaccharide is now a drug! What comes next?

M Petitou et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)

Article Biotechnology & Applied Microbiology

Glycomics: A pathway to a class of new and improved therapeutics

Z Shriver et al.

NATURE REVIEWS DRUG DISCOVERY (2004)

Review Chemistry, Medicinal

Endotoxins: Relationships between structure, function, and activity

K Brandenburg et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2004)

Review Biochemistry & Molecular Biology

Progress towards development of a cholera subunit vaccine

RK Taylor et al.

CHEMISTRY & BIODIVERSITY (2004)

Article Biochemistry & Molecular Biology

Synthetic glycoprotein mimics inhibit L-selectin-mediated rolling and promote L-selectin shedding

P Mowery et al.

CHEMISTRY & BIOLOGY (2004)

Review Biochemistry & Molecular Biology

Physicochemical properties of bacterial glycopolymers in relation to bioactivity

K Brandenburg et al.

CARBOHYDRATE RESEARCH (2003)

Review Biochemistry & Molecular Biology

New structural insights into carbohydrate-protein interactions from NMR spectroscopy

H Kogelberg et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2003)

Review Biochemistry & Molecular Biology

Carbohydrate microarrays - a new set of technologies at the frontiers of glycomics

T Feizi et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2003)

Article Chemistry, Multidisciplinary

Toward fully synthetic N-linked glycoproteins

JS Miller et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)

Article Biochemistry & Molecular Biology

Preparation and immunological studies of protein conjugates of N-acylneuraminic acids

P Chefalo et al.

GLYCOCONJUGATE JOURNAL (2003)

Article Chemistry, Multidisciplinary

Synthesis of sugar arrays in microtiter plate

F Fazio et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)

Review Biochemistry & Molecular Biology

Clusters, bundles, arrays and lattices: novel mechanisms for lectin-saccharide-mediated cellular interactions

CF Brewer et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2002)

Review Biochemistry & Molecular Biology

Carbohydrate-binding proteins in cancer, and their ligands as therapeutic agents

P Nangia-Makker et al.

TRENDS IN MOLECULAR MEDICINE (2002)

Review Chemistry, Multidisciplinary

Glycosylation and the complement system

GE Ritchie et al.

CHEMICAL REVIEWS (2002)

Review Chemistry, Multidisciplinary

Recent developments of transition-state analogue glycosidase inhibitors of non-natural product origin

VH Lillelund et al.

CHEMICAL REVIEWS (2002)

Review Biotechnology & Applied Microbiology

Targeting glycosylation as a therapeutic approach

RA Dwek et al.

NATURE REVIEWS DRUG DISCOVERY (2002)

Article Biotechnology & Applied Microbiology

The bittersweet promise of glycobiology

A Dove

NATURE BIOTECHNOLOGY (2001)

Article Chemistry, Multidisciplinary

Total syntheses of tumor-related antigens N3: Probing the feasibility limits of the glycal assembly method

HM Kim et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2001)

Review Biotechnology & Applied Microbiology

Emerging themes in medicinal glycoscience

KM Koeller et al.

NATURE BIOTECHNOLOGY (2000)

Review Biochemistry & Molecular Biology

Discovery and development of GS 4104 (oseltamivir): An orally active influenza neuraminidase inhibitor

W Lew et al.

CURRENT MEDICINAL CHEMISTRY (2000)

Review Chemistry, Organic

Recent developments in oligosaccharide synthesis

BG Davis

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (2000)