相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。An inexpensive and portable microchip-based platform for integrated RT-PCR and capillary electrophoresis
Govind V. Kaigala et al.
ANALYST (2008)
Detection of kinase translocation using microfluidic electroporative flow cytometry
Jun Wang et al.
ANALYTICAL CHEMISTRY (2008)
Competitive immunoassays for simultaneous detection of metabolites and proteins using micromosaic patterning
Brian M. Murphy et al.
ANALYTICAL CHEMISTRY (2008)
A digital microfluidic approach to homogeneous enzyme assays
Elizabeth M. Miller et al.
ANALYTICAL CHEMISTRY (2008)
The FDA critical path initiative and its influence on new drug development
Janet Woodcock et al.
ANNUAL REVIEW OF MEDICINE (2008)
Using living radical polymerization to enable facile incorporation of materials in microfluidic cell culture devices
Helen A. Simms et al.
BIOMATERIALS (2008)
Microfluidics for drug discovery and development: From target selection to product lifecycle management
Lifeng Kang et al.
DRUG DISCOVERY TODAY (2008)
Electrophoretic separations on microfluidic chips
Dapeng Wu et al.
JOURNAL OF CHROMATOGRAPHY A (2008)
Rapid, continuous purification of proteins in a microfluidic device using genetically-engineered partition tags
Robert J. Meagher et al.
LAB ON A CHIP (2008)
Rapid screening of membrane protein activity: electrophysiological analysis of OmpF reconstituted in proteoliposomes
Mohamed Kreir et al.
LAB ON A CHIP (2008)
In-situ synthesis of poly(dimethylsiloxane)-gold nanoparticles composite films and its application in microfluidic systems
Qing Zhang et al.
LAB ON A CHIP (2008)
Development of perfusion-based micro 3-D cell culture platform and its application for high throughput drug testing
Min-Hsien Wu et al.
SENSORS AND ACTUATORS B-CHEMICAL (2008)
Microfluidic self-assembly of tumor spheroids for anticancer drug discovery
Liz Y. Wu et al.
BIOMEDICAL MICRODEVICES (2008)
A high throughput perfusion-based microbioreactor platform integrated with pneumatic micropumps for three-dimensional cell culture
Min-Hsien Wu et al.
BIOMEDICAL MICRODEVICES (2008)
A cell culturing system that integrates the cell loading function on a single platform and evaluation of the pulsatile pumping effect on cells
J. Y. Kim et al.
BIOMEDICAL MICRODEVICES (2008)
Development of an osteoblast-based 3D continuous-perfusion microfluidic system for drug screening
Kihoon Jang et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2008)
An overview of automated systems relevant in pharmaceutical salt screening
Lokesh Kumar et al.
DRUG DISCOVERY TODAY (2007)
A microfluidic device for parallel 3-D cell cultures in asymmetric environments
Thomas Frisk et al.
ELECTROPHORESIS (2007)
Generation of monodisperse alginate microbeads and in situ encapsulation of cell in microfluidic device
Chang-Hyung Choi et al.
BIOMEDICAL MICRODEVICES (2007)
Microfluidic systems integrated with two-dimensional surface plasmon resonance phase imaging systems for microarray immunoassay
Kuo-Hoong Lee et al.
BIOSENSORS & BIOELECTRONICS (2007)
Microfabricated two-dimensional electrophoresis device for differential protein expression profiling
Charles A. Emrich et al.
ANALYTICAL CHEMISTRY (2007)
Controlled production of emulsion drops using an electric field in a flow-focusing microfluidic device
Haejune Kim et al.
APPLIED PHYSICS LETTERS (2007)
Convergence of quantum dot barcodes with microfluidics and signal processing for multiplexed high-throughput infectious disease diagnostics
Jesse M. Klostranec et al.
NANO LETTERS (2007)
Monolithic integration of well-ordered nanoporous structures in the microfluidic channels for bioseparation
Chiung-Wen Kuo et al.
JOURNAL OF CHROMATOGRAPHY A (2007)
High throughput solubility measurement in drug discovery and development
Jochem Alsenz et al.
ADVANCED DRUG DELIVERY REVIEWS (2007)
Free flow acoustophoresis:: Microfluidic-based mode of particle and cell separation
Filip Petersson et al.
ANALYTICAL CHEMISTRY (2007)
Assessing a novel microfluidic interface for shotgun proteome analyses
An Staes et al.
JOURNAL OF SEPARATION SCIENCE (2007)
Micromachined glass apertures for artificial lipid bilayer formation in a microfluidic system
Mairi E. Sandison et al.
JOURNAL OF MICROMECHANICS AND MICROENGINEERING (2007)
A cell-laden microfluidic hydrogel
Yibo Ling et al.
LAB ON A CHIP (2007)
Microfluidic patterning for fabrication of contractile cardiac organoids
Ali Khademhosseini et al.
BIOMEDICAL MICRODEVICES (2007)
Microfluidic immunoassays as rapid saliva-based clinical diagnostics
Amy E. Herr et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
A microfluidic platform for 3-dimensional cell culture and cell-based assays
Minseok S. Kim et al.
BIOMEDICAL MICRODEVICES (2007)
A trap-and-release integrated microfluidic system for dynamic microarray applications
Wei-Heong Tan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Electrophysiological recordings of single ion channels in planar lipid bilayers using a polymethyl methacrylate microfluidic chip
Hiroaki Suzuki et al.
BIOSENSORS & BIOELECTRONICS (2007)
Generation of dynamic chemical signals with microfluidic C-DACs
L. Chen et al.
LAB ON A CHIP (2007)
Cell-based high content screening using an integrated microfluidic device
Nannan Ye et al.
LAB ON A CHIP (2007)
A novel 3D mammalian cell perfusion-culture system in microfluidic channels
Yi-Chin Toh et al.
LAB ON A CHIP (2007)
Tuning microchannel wettability and fabrication of multiple-step Laplace valves
Go Takei et al.
LAB ON A CHIP (2007)
Gradient generation by an osmotic pump and the behavior of human mesenchymal stem cells under the fetal bovine serum concentration gradient
Joong Yull Park et al.
LAB ON A CHIP (2007)
Microfluidic separation and capture of analytes for single-molecule spectroscopy
Samuel Kim et al.
LAB ON A CHIP (2007)
A high-throughput microfluidic real-time gene expression living cell array
Kevin R. King et al.
LAB ON A CHIP (2007)
A decade of microfluidic analysis coupled with electrospray mass spectrometry: An overview
Sander Koster et al.
LAB ON A CHIP (2007)
High-throughput screening of enzyme inhibition using an inhibitor gradient generated in a microchannel
Elena Garcia et al.
LAB ON A CHIP (2007)
Addressing a vascular endothelium array with blood components using underlying microfluidic channels
Luiza I. Genes et al.
LAB ON A CHIP (2007)
High-density microfluidic arrays for cell cytotoxicity analysis
Zhanhui Wang et al.
LAB ON A CHIP (2007)
Microfluidics at the crossroad with point-of-care diagnostics
Vincent Linder
ANALYST (2007)
Modification of poly (dimethylsiloxane) microfluidic channels with silica nanoparticles based on layer-by-layer assembly technique
Wei Wang et al.
JOURNAL OF CHROMATOGRAPHY A (2006)
A microfluidic-FCS platform for investigation on the dissociation of Sp1-DNA complex by doxorubicin
Hsin-Chih Yeh et al.
NUCLEIC ACIDS RESEARCH (2006)
A microfluidics-based mobility shift assay to discover new tyrosine phosphatase inhibitors
Dominique Perrin et al.
JOURNAL OF BIOMOLECULAR SCREENING (2006)
Integration of nanoporous membranes for sample filtration/preconcentration in microchip electrophoresis
Zhicheng Long et al.
ELECTROPHORESIS (2006)
Pharmaeogenomics of the polyamine analog 3,8,13,18-tetraaza-10,11-[(E)-1,2-cyclopropyl] eicosane tetrahydrochloride, CGC-11093, in the colon adenocarcinoma cell line HCT116
Natalia A. Ignatenko et al.
TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2006)
A monolithically three-dimensional flow-focusing device for formation of single/double emulsions in closed/open microfluidic systems
Shih-Hao Huang et al.
JOURNAL OF MICROMECHANICS AND MICROENGINEERING (2006)
A label-free protein microfluidic array for parallel immunoassays
Zhan-Hui Wang et al.
ELECTROPHORESIS (2006)
Microfluidic sequential injection analysis in a short capillary
Wen-Bin Du et al.
ANALYTICAL CHEMISTRY (2006)
Automated formation of lipid-bilayer membranes in a microfluidic device
Noah Malmstadt et al.
NANO LETTERS (2006)
Quantum dot-based fluorescence resonance energy transfer with improved FRET efficiency in capillary flows
Chun-yang Zhang et al.
ANALYTICAL CHEMISTRY (2006)
Microfluidic liquid chromatography system for proteomic applications and biomarker screening
Iulia M. Lazar et al.
ANALYTICAL CHEMISTRY (2006)
Fabrication of cell-containing hydrogel microstructures inside microfluidic devices that can be used as cell-based biosensors
Won-Gun Koh et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2006)
Microfluidic diagnostic technologies for global public health
Paul Yager et al.
NATURE (2006)
Assay development and screening of a serine/threonine kinase in an on-chip mode using caliper nanofluidics technology
Dominique Perrin et al.
JOURNAL OF BIOMOLECULAR SCREENING (2006)
Differential gene expression profiles and real-time measurements of growth parameters in Saccharomyces cerevisiae grown in microliter-scale bioreactors equipped with internal stirring
Paolo Boccazzi et al.
BIOTECHNOLOGY PROGRESS (2006)
Universal microfluidic gradient generator
Daniel Irimia et al.
ANALYTICAL CHEMISTRY (2006)
Nanoliter scale microbioreactor array for quantitative cell biology
PJ Lee et al.
BIOTECHNOLOGY AND BIOENGINEERING (2006)
Generation of complex, static solution gradients in microfluidic channels
HK Wu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
QPatch: the past, present and future of automated patch clamp
C Mathes
EXPERT OPINION ON THERAPEUTIC TARGETS (2006)
On-chip millionfold sample stacking using transient isotachophoresis
B Jung et al.
ANALYTICAL CHEMISTRY (2006)
The use of poly(dimethylsiloxane) surface modification with gold nanoparticles for the microchip electrophoresis
AJ Wang et al.
TALANTA (2006)
Elucidating in vitro cell-cell interaction using a microfluidic coculture system
CW Wei et al.
BIOMEDICAL MICRODEVICES (2006)
Gelatin based microfluidic devices for cell culture
A Paguirigan et al.
LAB ON A CHIP (2006)
A simple, valveless microfluidic sample preparation device for extraction and amplification of DNA from nanoliter-volume samples
LA Legendre et al.
ANALYTICAL CHEMISTRY (2006)
Characterization of a membrane-based gradient generator for use in cell-signaling studies
VV Abhyankar et al.
LAB ON A CHIP (2006)
Highly reproducible method of planar lipid bilayer reconstitution in polymethyl methacrylate microfluidic chip
H Suzuki et al.
LANGMUIR (2006)
A well-mixed, polymer-based microbioreactor with integrated optical measurements
ZY Zhang et al.
BIOTECHNOLOGY AND BIOENGINEERING (2006)
Electrochemical mutagen screening using microbial chip
N Matsui et al.
BIOSENSORS & BIOELECTRONICS (2006)
Design and performance of a 24-station high throughput microbioreactor
P Harms et al.
BIOTECHNOLOGY AND BIOENGINEERING (2006)
Microfluidic technologies for MALDI-MS in proteomics
Don L. DeVoe et al.
ELECTROPHORESIS (2006)
Electrochemical fabrication of conducting polymer nanowires in an integrated microfluidic system
Jun Wang et al.
CHEMICAL COMMUNICATIONS (2006)
Microchemostat - microbial continuous culture in a polymer-based, instrumented microbioreactor
Zhiyu Zhang et al.
LAB ON A CHIP (2006)
An integrated digital microfluidic chip for multiplexed proteomic sample preparation and analysis by MALDI-MS
Hyejin Moon et al.
LAB ON A CHIP (2006)
Microbioreactor arrays with integrated mixers and fluid injectors for high-throughput experimentation with pH and dissolved oxygen control
Harry L. T. Lee et al.
LAB ON A CHIP (2006)
Dynamic single cell culture array
Dino Di Carlo et al.
LAB ON A CHIP (2006)
Nanofilter array chip for fast gel-free biomolecule separation
JP Fu et al.
APPLIED PHYSICS LETTERS (2005)
Microfluidics for processing surfaces and miniaturizing biological assays
E Delamarche et al.
ADVANCED MATERIALS (2005)
A microscale in vitro physiological model of the liver:: Predictive screens for drug metabolism and enzyme induction
A Sivaraman et al.
CURRENT DRUG METABOLISM (2005)
A concept for miniaturized 3-D cell culture using an extracellular matrix gel
T Frisk et al.
ELECTROPHORESIS (2005)
Microfluidic technologies in drug discovery
J Pihl et al.
DRUG DISCOVERY TODAY (2005)
Gene expression perturbation in vitro - A growing case for three-dimensional (3D) culture systems
A Birgersdotter et al.
SEMINARS IN CANCER BIOLOGY (2005)
A novel method for high-throughput reduction of compounds through automated sequential injection into a continuous-flow microfluidic reactor
R Jones et al.
QSAR & COMBINATORIAL SCIENCE (2005)
Leveraging the advantages offered by microfluidics to enhance the drug discovery process
SYFW Hawkes et al.
QSAR & COMBINATORIAL SCIENCE (2005)
Million-fold preconcentration of proteins and peptides by nanofluidic filter
YC Wang et al.
ANALYTICAL CHEMISTRY (2005)
Mammalian electrophysiology on a microfluidic platform
C Ionescu-Zanetti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Agonist-induced calcium response in single human platelets assayed in a microfluidic device
L Tran et al.
ANALYTICAL BIOCHEMISTRY (2005)
A novel single-step fabrication technique to create heterogeneous poly(ethylene glycol) hydrogel microstructures containing multiple phenotypes of mammalian cells
JC Zguris et al.
LANGMUIR (2005)
Monodisperse double emulsions generated from a microcapillary device
AS Utada et al.
SCIENCE (2005)
Bioprocess intensification in flow-through monolithic microbioreactors with immobilized bacteria
G Akay et al.
BIOTECHNOLOGY AND BIOENGINEERING (2005)
Dissection of melanogenesis with small molecules identifies prohibitin as a regulator
JR Snyder et al.
CHEMISTRY & BIOLOGY (2005)
Low O2 tensions and the prevention of differentiation of hES cells
T Ezashi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Label-free detection of small-molecule-protein interactions by using nanowire nanosensors
WU Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Continuous perfusion microfluidic cell culture array for high-throughput cell-based assays
PJ Hung et al.
BIOTECHNOLOGY AND BIOENGINEERING (2005)
Microfluidic separation of satellite droplets as the basis of a monodispersed micron and submicron emulsification system
YC Tan et al.
LAB ON A CHIP (2005)
Development of a multiplexed microbioreactor system for high-throughput bioprocessing
N Szita et al.
LAB ON A CHIP (2005)
A novel high aspect ratio microfluidic design to provide a stable and uniform microenvironment for cell growth in a high throughput mammalian cell culture array
PJ Hung et al.
LAB ON A CHIP (2005)
Gentle cell trapping and release on a microfluidic chip by in situ alginate hydrogel formation
T Braschler et al.
LAB ON A CHIP (2005)
Development of a microscale cell culture analog to probe naphthalene toxicity
K Viravaidya et al.
BIOTECHNOLOGY PROGRESS (2004)
Incorporation of 3T3-L1 cells to mimic bioaccumulation in a microscale cell culture analog device for toxicity studies
K Viravaidya et al.
BIOTECHNOLOGY PROGRESS (2004)
The design and fabrication of three-chamber microscale cell culture analog devices with integrated dissolved oxygen sensors
A Sin et al.
BIOTECHNOLOGY PROGRESS (2004)
Design of a compact disk-like microfluidic platform for enzyme-linked immunosorbent assay
S Lai et al.
ANALYTICAL CHEMISTRY (2004)
High-throughput microfluidic mixing and multiparametric cell sorting for bioactive compound screening
SM Young et al.
JOURNAL OF BIOMOLECULAR SCREENING (2004)
Hard and soft micromachining for BioMEMS: review of techniques and examples of applications in microfluidics and drug delivery
B Ziaie et al.
ADVANCED DRUG DELIVERY REVIEWS (2004)
A self-priming microfluidic diaphragm pump capable of recirculation fabricated by combining soft lithography and traditional machining
A Sin et al.
BIOTECHNOLOGY AND BIOENGINEERING (2004)
Death in the third dimension: apoptosis regulation and tissue architecture
N Zahir et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2004)
Photopolymerization in microfluidic gradient generators: Microscale control of substrate compliance to manipulate cell response
N Zaari et al.
ADVANCED MATERIALS (2004)
Membrane-aerated microbioreactor for high-throughput bioprocessing
A Zanzotto et al.
BIOTECHNOLOGY AND BIOENGINEERING (2004)
Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips
J Huang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Controlled production of monodisperse double emulsions by two-step droplet breakup in microfluidic devices
S Okushima et al.
LANGMUIR (2004)
Quantitative mass spectrometric determination of methylphenidate concentration in urine using an electrospray ionization source integrated with a polymer microchip
YN Yang et al.
ANALYTICAL CHEMISTRY (2004)
The role of hypoxia-induced factors in tumor progression
P Vaupel
ONCOLOGIST (2004)
Generation of dynamic temporal and spatial concentration gradients using microfluidic devices
F Lin et al.
LAB ON A CHIP (2004)
Proteomics-based target identification - Bengamides as a new class of methionine aminopeptidase inhibitors
H Towbin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Advances in high content screening for drug discovery
KA Giuliano et al.
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2003)
Microfluidic combinatorial chemistry
P Watts et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2003)
Integration of cell culture and microfabrication technology
TH Park et al.
BIOTECHNOLOGY PROGRESS (2003)
Lab-on-a-chip for drug development
BH Weigl et al.
ADVANCED DRUG DELIVERY REVIEWS (2003)
Light directed massively parallel on-chip synthesis of peptide arrays with t-Boc chemistry
XL Gao et al.
PROTEOMICS (2003)
Cell interactions with three-dimensional matrices
E Cukierman et al.
CURRENT OPINION IN CELL BIOLOGY (2002)
Two- versus three-dimensional in vitro differentiation of human pulp cells into odontoblastic cells
J Camps et al.
CONNECTIVE TISSUE RESEARCH (2002)
Microarrays of cells expressing defined cDNAs
J Ziauddin et al.
NATURE (2001)
Generation of gradients having complex shapes using microfluidic networks
SKW Dertinger et al.
ANALYTICAL CHEMISTRY (2001)
Enhanced cartilage tissue engineering by sequential exposure of chrondrocytes to FGF-2 during 2D expansion and BMP-2 during 3D cultivation
I Martin et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2001)
Generation of solution and surface gradients using microfluidic systems
NL Jeon et al.
LANGMUIR (2000)
分享论文
