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Priti Kumar et al.
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Rong-Qin Huang et al.
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E. R. Dorsey et al.
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Six-month continuous intraputamenal infusion toxicity study of recombinant methionyl human glial cell line-derived neurotrophic factor (r-metHuGDNF) in rhesus monkeys
David N. Hovland et al.
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Y Machida et al.
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FP Manfredsson et al.
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Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease
AE Lang et al.
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A Ambruosi et al.
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TK Vyas et al.
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Astrocyte-endothelial interactions at the blood-brain barrier
NJ Abbott et al.
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L Costantino et al.
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RL Buckner et al.
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M Sun et al.
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GP Lim et al.
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R De Rosa et al.
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WQ Sun et al.
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L Illum
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I Ferrer et al.
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Brain uptake of thiamine-coated nanoparticles
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Alzheimer disease in the US population - Prevalence estimates using the 2000 census
LE Hebert et al.
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K Bogman et al.
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Y Zhang et al.
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