Oncolytic adenoviruses expressing interleukin: a novel antitumour approach

Areas covered in this review: We provide an overview of specifications for a novel antitumour approach by oncolytic adenoviruses expressing interleukin and discuss recent progresses in this field. What the reader will gain: Creating an armed therapeutic viral platform, where the lytic property of viral infection coupled to virus-mediated interleukin delivery, may enhance the potential of virus-based therapeutics. Take home message: Oncolytic adenoviruses expressing interleukin may be a novel approach for tumour treatment. Combining advances in oncolytic adenoviruses with interleukin will open new avenues for treatment of human tumour.