相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Gene transfer to the lung: Lessons learned from more than 2 decades of CF gene therapy
Uta Griesenbach et al.
ADVANCED DRUG DELIVERY REVIEWS (2009)
Progress and Prospects: The design and production of plasmid vectors
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Adeno-associated virus-targeted disruption of the CFTR gene in cloned ferrets
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JOURNAL OF CLINICAL INVESTIGATION (2008)
Production of CFTR-null and CFTR-ΔF508 heterozygous pigs by adeno-associated virus-mediated gene targeting and somatic cell nuclear transfer
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In vivo gene delivery in the mouse lung with lactosylated polyethylenimine, questioning the relevance of in vitro experiments
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Silencing of episomal transgene expression in liver by plasmid bacterial backbone DNA is independent of CpG methylation
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Cell surface nucleolin serves as receptor for DNA nanoparticles composed of pegylated polylysine and DNA
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CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression
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Expression of CFTR from a ciliated cell-specific promoter is ineffective at correcting nasal potential difference in CF mice
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Targeted Sleeping Beauty transposition in human cells
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Electroporation-mediated transfer of plasmids to the lung results in reduced TLR9 signaling and inflammation
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Use of ultrasound to enhance nonviral lung gene transfer in vivo
S. Xenariou et al.
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Electroporation enhances reporter gene expression following delivery of naked plasmid DNA to the lung
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Optimizing aerosol gene delivery and expression in the ovine lung
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Gene transfer of hepatocyte growth factor by electroporation reduces bleomycin-induced lung fibrosis
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The φC31 integrase system for gene therapy
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CURRENT GENE THERAPY (2006)
Analysis and optimization of the cationic lipid component of a lipid/peptide vector formulation for enhanced transfection in vitro and in vivo
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Using magnetic forces to enhance non-viral gene transfer to airway epithelium in vivo
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In vivo electroporation and ubiquitin promoter -: a protocol for sustained gene expression in the lung
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Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer
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Electroporation-mediated interteukin-10 overexpression in skeletal muscle reduces acute rejection in rat cardiac allografts
R Tavakoli et al.
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Gene transfer of CFTR to airway epithelia:: low levels of expression are sufficient to correct Cl- transport and overexpression can generate basolateral CFTR
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Detection of plasmid DNA vectors following gene transfer to the murine airways
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Electrohydrodynamic comminution: A novel technique for the aerosolisation of plasmid DNA
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Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis
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Methodological optimization of polyethylenimine (PEI)-based gene delivery to the lungs of mice via aerosol application
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Lactosylated polyethylenimine for gene transfer into airway epithelial cells:: role of the sugar moiety in cell delivery and intracellular trafficking of the complexes
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Contribution of toll-like receptor 9 signaling to the acute inflammatory response to nonviral vectors
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Role of nucleolin in human parainfluenza virus type 3 infection of human lung epithelial cells
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Compacted DNA nanoparticles administered to the nasal mucosa of cystic fibrosis subjects are safe and demonstrate partial to complete cystic fibrosis transmembrane regulator reconstitution
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Systematic identification of sense-antisense transcripts in mammalian cells
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Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Targeting expression of a transgene to the airway surface epithelium using a ciliated cell-specific promoter
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MOLECULAR THERAPY (2003)
Transfection efficiency and toxicity following delivery of naked plasmid DNA and cationic lipid-DNA complexes to ovine lung segments
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A comparison of linear and branched polyethylenimine (PEI) with DCChol/DOPE liposomes for gene delivery to epithelial cells in vitro and in vivo
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Electroporation as a method for high-level nonviral gene transfer to the lung
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Formation of LID vector complexes in water alters physicochemical properties and enhances pulmonary gene expression in vivo
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Transfection of airway epithelium by stable PEGylated poly-L-lysine DNA nanoparticles in vivo
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Minimal toxicity of stabilized compacted DNA nanoparticles in the murine lung
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Evaluation of a porcine model for pulmonary gene transfer using a novel synthetic vector
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CpG-depleted plasmid DNA vectors with enhanced safety and long-term gene expression in vivo
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PEDIATRIC PULMONOLOGY (2002)
In vivo airway surface liquid Cl- analysis with solid-state electrodes
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Increased persistence of lung gene expression using plasmids containing the ubiquitin C or elongation factor 1α promoter
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High and sustained transgene expression in vivo from plasmid vectors containing a hybrid ubiquitin promoter
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Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis
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Safety and biological efficacy of a lipid-CFTR complex for gene transfer in the nasal epithelium of adult patients with cystic fibrosis
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Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs
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