期刊
EXPERIMENTAL PARASITOLOGY
卷 118, 期 1, 页码 10-16出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.exppara.2007.08.004
关键词
-
类别
资金
- Biotechnology and Biological Sciences Research Council [BB/C507145/1] Funding Source: Medline
It has been more than eight years since the discovery of mitosomes (mitochondrial remnant organelles) in the intestinal human pathogen EntaMoeba histolytica. Despite detailed knowledge about the biochemistry of this parasite and the completion of the E histolytica genome sequencing project no physiological function has yet been unequivocally assigned to these organelles. Entamoeba mitosomes seem to be the most degenerate of all endosymbiosis-derived organelles studied to date. They do not appear to participate in energy metabolism and may have dispensed completely with the proteins required for iron-sulphur cluster biosynthesis. However, the large number of mitosomes found in E histolytica trophozoites hints at a significant biological role for these organelles in their natural environment. Identifying the protein complement of mitosomes will provide answers as to their biological significance and the reason(s) for their retention in this parasite. (c) 2007 Elsevier Inc. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据