期刊
EXPERIMENTAL CELL RESEARCH
卷 323, 期 1, 页码 1-6出版社
ELSEVIER INC
DOI: 10.1016/j.yexcr.2013.12.025
关键词
miR-92a family; Target genes; Regulation; Tumors
资金
- Natural Science Foundation of China [81072063]
- Science and technology Foundation of the Dalian, liaoning, China [2012E15SF159]
The miR-92a family, including miR-25, miR-92a-1, miR-92a-2 and miR-363, arises from three different paralog clusters miR-17-92, miR-106a-363, and miR-106b-25 that are highly conservative in the process of evolution, and it was thought as a group of microRNAs (miRNAs) correlated with endothelial cells. Aberrant expression of miR-92a family was detected in multiple cancers, and the disturbance of miR-92a family was related with tumorigenesis and tumor development. In this review, the progress on the relationship between miR-92a family and their target genes and malignant tumors will be summarized. (C) 2013 The Authors. Published by Elsevier Inc. All rights reserved.
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