期刊
EXPERIMENTAL CELL RESEARCH
卷 319, 期 11, 页码 1644-1649出版社
ELSEVIER INC
DOI: 10.1016/j.yexcr.2013.03.005
关键词
Cancer; Inflammation; B cells; Leukocytes; Myeloid cells
资金
- NIH/NCI
- DOD BCRP Era of Hope Scholar Expansion Award
- Susan B Komen Foundation
- Breast Cancer Research Foundation
- [T32I078903-04]
B cells have recently been appreciated as paracrine mediators of solid tumor development. Their ability to influence various hallmarks of cancer development, aside from antigen presentation, can be attributed to the diversity of soluble mediators they express, including cytokines and immunoglobulins, that can act directly and indirectly on the diversity of leukocyte subsets that infiltrate developing tumors, evolving neoplastic cells, as well as select T cell populations in secondary lymphoid organs and within tumor stroma. Herein, we review the literature supporting these interactions and discuss novel approaches to ameliorate protumoral B cell effects for anti-cancer therapy. (c) 2013 Elsevier Inc. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据