期刊
EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY
卷 62, 期 5, 页码 539-542出版社
ELSEVIER GMBH
DOI: 10.1016/j.etp.2009.07.005
关键词
Ochratoxin A; Human blood; Healthy individuals; Tunisia
资金
- Le Ministere Tunisien l'Enseignement Superieur et de la Recherche Scientifique et de la Technologie (Laboratory of Biology and Toxicology, Research Unit, Toxicology and Environment)
- Le Ministere Tunisien de la defense (Department of Biochemistry, Military Hospital of Tunis
Human exposure to Ochratoxin A (OTA) has been investigated in many Mediterranean countries, where OTA was found with a higher frequency in foodstuffs and blood samples. The aim of this study was to assess OTA concentrations in human blood serum in Tunisia and to evaluate the impact of several factors (age, origin, sex) on these prevalence reference values. One hundred and seven blood serum samples from healthy subjects were analyzed using a solid-phase extraction linked to a high-performance liquid chromatography (HPLC) method. OTA values ranged from 0 to 3.43 ng/mL with a mean value of 0.49 +/- 0.67 ng/mL. OTA levels were higher in the Sahal group. Our results reflect OTA concentration previously detected for human blood in Tunisia. Origin, but not age and sex, may affect the OTA reference values. (C) 2009 Elsevier GmbH. All rights reserved.
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