相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Inhibiting aberrant Stat3 function with molecular therapeutics: a progress report
Sina Haftchenary et al.
ANTI-CANCER DRUGS (2011)
Stat3 as a Therapeutic Target for the Treatment of Psoriasis: A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor
Ken Miyoshi et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2011)
Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms
Stephen T. Oh et al.
BLOOD (2010)
STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells
Inbal Hazan-Halevy et al.
BLOOD (2010)
MS-1020 is a novel small molecule that selectively inhibits JAK3 activity
Byung-Hak Kim et al.
BRITISH JOURNAL OF HAEMATOLOGY (2010)
NSC114792, a novel small molecule identified through structure-based computational database screening, selectively inhibits JAK3
Byung-Hak Kim et al.
MOLECULAR CANCER (2010)
Molecular disruption of oncogenic signal transducer and activator of transcription 3 (STAT3) protein
Steven Fletcher et al.
BIOCHEMISTRY AND CELL BIOLOGY (2009)
The benzoxathiolone LYR-71 down-regulates interferon-γ-inducible pro-inflammatory genes by uncoupling tyrosine phosphorylation of STAT-1 in macrophages
E-Y Chung et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Prospect of JAK2 inhibitor therapy in myeloproliferative neoplasms
Ehab Atallah et al.
EXPERT REVIEW OF ANTICANCER THERAPY (2009)
JAK3 Inhibition Significantly Attenuates Psoriasiform Skin Inflammation in CD18 Mutant PL/J Mice
Betty Y. Chang et al.
JOURNAL OF IMMUNOLOGY (2009)
JAK mutations in high-risk childhood acute lymphoblastic leukemia
Charles G. Mullighan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
STATs in cancer inflammation and immunity: a leading role for STAT3
Hua Yu et al.
NATURE REVIEWS CANCER (2009)
Novel iminobenzoxathiolone compound inhibits nuclear factor-κB activation targeting inhibitory κB kinase β and down-regulating interleukin-1β expression in lipopolysaccharide-activated macrophages
Min Hee Kim et al.
BIOCHEMICAL PHARMACOLOGY (2008)
STAT3 as a target for inducing apoptosis in solid and hematological tumors
Khandaker Al Zaid Siddiquee et al.
CELL RESEARCH (2008)
LYR71, a derivative of trimeric resveratrol, inhibits tumorigenesis by blocking STAT3-mediated matrix metalloproteinase 9 expression
Ja Eun Kim et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2008)
Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia
Elisabetta Flex et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome
Dani Bercovich et al.
LANCET (2008)
A small-molecule compound identified through a cell-based screening inhibits JAK/STAT pathway signaling in human cancer cells
Byung Hak Kim et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Benzoxathiole derivative blocks lipopolysaccharide-induced nuclear factor-κB activation and nuclear factor-κB-regulated gene transcription through inactivating inhibitory κB kinase β
Byung Hak Kim et al.
MOLECULAR PHARMACOLOGY (2008)
Inteferons pen the JAK-STAT pathway
Christian Schindler et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2008)
Nucleocytoplasmic shuttling of persistently activated STAT3
Andreas Herrmann et al.
JOURNAL OF CELL SCIENCE (2007)
A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo
A. Iwamaru et al.
ONCOGENE (2007)
JAK/STAT signalling in Drosophila:: insights into conserved regulatory and cellular functions
Natalia I. Arbouzova et al.
DEVELOPMENT (2006)
Activating alleles of JAK3 in acute megakaryoblastic leukemia
Denise K. Walters et al.
CANCER CELL (2006)
Signal transducers and activators of transcription (STATs): Novel targets of chemopreventive and chemotherapeutic drugs
L Klampfer
CURRENT CANCER DRUG TARGETS (2006)
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
C James et al.
NATURE (2005)
JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis
LS Steelman et al.
LEUKEMIA (2004)
A new modality for immunosuppression: Targeting the JAK/STAT pathway
JJ O'Shea et al.
NATURE REVIEWS DRUG DISCOVERY (2004)
Roles of activated Src and Stat3 signaling in melanoma tumor cell growth
G Niu et al.
ONCOGENE (2002)
Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells
R Garcia et al.
ONCOGENE (2001)
Inhibition of caspase-3-mediated poly(ADP-ribose) polymerase (PARP) apoptotic cleavage by human PARP autoantibodies and effect on cells undergoing apoptosis
P Decker et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)