期刊
EXERCISE AND SPORT SCIENCES REVIEWS
卷 42, 期 2, 页码 76-81出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1249/JES.0000000000000013
关键词
skeletal muscle; 25-hydroxyvitamin D; aging; vitamin D receptor; vitamin D
资金
- NHLBI [T32HL69772]
In this review, we summarize current evidence for a direct effect of vitamin D on skeletal muscle. A number of studies identify the receptor for 1,25-dihydroxyvitamin-D-3 (vitamin D receptor (VDR)) and the enzyme CYP27B1 (1-alpha-hydroxylase) in muscle. We hypothesize that vitamin D acts on myocytes via the VDR, and we examine proposed effects on myocyte proliferation, differentiation, growth, and inflammation.
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