期刊
EXERCISE AND SPORT SCIENCES REVIEWS
卷 41, 期 2, 页码 116-122出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/JES.0b013e3182877deb
关键词
exercise; hematopoietic stem cell; niche; hormesis; exercise training; radioprotection; bone marrow transplantation
资金
- CIHR
- NSERC
- CIHR Canada Graduate Scholarship
DE LISIO, M. and G. PARISE. Exercise and hematopoietic stem and progenitor cells: protection, quantity, and function. Exerc. Sport Sci. Rev., Vol. 41, No. 2, pp. 116-122, 2013. The effects of exercise on mature cells of the hematopoietic lineage have been well characterized; however, the effects of exercise on the more primitive cells of the hematopoietic system are unknown. Here, we propose that the benefits of exercise apply to hematopoietic progenitors and that exercise increases hematopoietic stem cell quantity primarily mediated via adaptations in the stem cell niche.
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