期刊
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
卷 16, 期 1, 页码 63-70出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jamda.2014.10.020
关键词
Cognitive stimulation therapy; dementia; cost; cost-effectiveness; randomized controlled trial; acetylcholinesterase inhibitors
资金
- National Institute for Health Research (NIHR) under its Programme Grants for Applied Research scheme [RP-PG-0606-1083]
Background: Cognitive Stimulation Therapy (CST) is effective and cost-effective for people with mild-to-moderate dementia when delivered biweekly over 7 weeks. Aims: To examine whether longer-term (maintenance) CST is cost-effective when added to usual care. Methods: Cost-effectiveness analysis within multicenter, single-blind, pragmatic randomized controlled trial; subgroup analysis for people taking acetylcholinesterase inhibitors (ACHEIs). A total of 236 participants with mild-to-moderate dementia received CST for 7 weeks. They were randomized to either weekly maintenance CST added to usual care or usual care alone for 24 weeks. Results: Although outcome gains were modest over 6 months, maintenance CST appeared cost-effective when looking at self-rated quality of life as primary outcome, and cognition (MMSE) and proxy-rated quality-adjusted life years as secondary outcomes. CST in combination with ACHEIs offered cost-effectiveness gains when outcome was measured as cognition. Conclusions: Continuation of CST is likely to be cost-effective for people with mild-to-moderate dementia. (C) 2015 AMDA - The Society for Post-Acute and Long-Term Care Medicine.
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