期刊
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
卷 65, 期 24, 页码 2601-2610出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jacc.2015.04.033
关键词
big data; cardiac electronic implantable devices; cardiac resynchronization therapy; device; mortality; survival; time in remote monitoring
资金
- St. Jude Medical
- Boston Scientific
- Sorin
- Biotronik
- Medtronic
- ARCA Biopharma
- Gilead
- Janssen
- ResMed
BACKGROUND Remote monitoring (RM) technology embedded within cardiac rhythm devices permits continuous monitoring, which may result in improved patient outcomes. OBJECTIVES This study used big data to assess whether RM is associated with improved survival and whether this is influenced by the type of cardiac device and/or its degree of use. METHODS We studied 269,471 consecutive U.S. patients implanted between 2008 and 2011 with pacemakers (PMs), implantable cardioverter-defibrillators (ICDs), or cardiac resynchronization therapy (CRT) with pacing capability (CRT-P)/defibrillation capability (CRT-D) with wireless RM. We analyzed weekly use and all-cause survival for each device type by the percentage of time in RM (% TRM) stratified by age. Socioeconomic influences on % TRM were assessed using 8 census variables from 2012. RESULTS The group had implanted PMs (n = 115,076; 43%), ICDs (n = 85,014; 32%), CRT-D (n = 61,475; 23%), and CRT-P (n = 7,906; 3%). When considered together, 127,706 patients (47%) used RM, of whom 67,920 (53%) had >= 75% TRM (high % TRM) and 59,786 (47%) <75% TRM (low % TRM); 141,765 (53%) never used RM (RM None). RM use was not affected by age or sex, but demonstrated wide geographic and socioeconomic variability. Survival was better in high % TRM versus RM None (hazard ratio [HR]: 2.10; p < 0.001), in high % TRM versus low % TRM (HR: 1.32; p < 0.001), and also in low % TRM versus RM None (HR: 1.58; p < 0.001). The same relationship was observed when assessed by individual device type. CONCLUSIONS RM is associated with improved survival, irrespective of device type (including PMs), but demonstrates a graded relationship with the level of adherence. The results support the increased application of RM to improve patient outcomes. (C) 2015 by the American College of Cardiology Foundation.
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